Wearable strain sensors are widespread in many fields, including the biomedical field where they are used for their stretchability and ability to be applied to non-regular surfaces. The study of the propagation speed of the pressure wave generated by the heartbeat within vessels, i.e., the Pulse Wave Velocity (PWV), is of significant relevance in this field to assess arterial stiffness, a parameter commonly used for the early diagnosis of cardiovascular diseases. In this context, arterial simulators are useful tools to study the relationship between the PWV and other hemodynamic quantities in vitro. This study aims to characterize novel strain sensors to assess their suitability within an arterial simulator capable of varying the stiffness of an arterial surrogate by varying the transmural pressure. Six sensors deposited on arterial surrogates by Aerosol Jet Printing technology were subjected to deformation through a load frame. The results show that the sensors were able to distinguish strains of 0.1%, the maximum strain was around 6–8%, and the fatigue strength depended strongly on the strain rate.

In the absence of standard procedures for testing 3D-printed soft polymers, an experimental protocol was proposed to assess the suitability of Flexible 80A Resin for a pediatric trachea anatomical 3D model for surgical simulation. Eighteen specimens printed via stereolithography are involved, including anatomical, cylindrical, and dog-bone shapes, to investigate the geometry effect on measured properties. Static tensile tests revealed that using standardized dog-bone specimens as a reference for the material’s Young’s modulus leads to a mean absolute percentage error (MAPE) up to 50% compared to anatomical specimens. Measurement uncertainty combined repeatability with input errors, and the ANOVA test confirmed the need for dedicated mechanical measurements when evaluating complex 3D-printed geometries. The study concludes the suitability of selected material: the average elastic modulus of anatomical specimens was 4.75 MPa, closely matching values reported for tracheal tissue in the literature, with a MAPE of only 2%. Dynamic mechanical tests showed trachea-like viscoelasticity: anatomical specimens were consistently stiffer and more dissipative than cylindrical ones. Creep tests confirmed the viscoelastic behavior simulating airway time scales. The anatomical specimens exhibit faster local relaxation, while cylindrical ones show slower long-term relaxation, both modeled by a two-element generalized Maxwell model (R² = 0.99 and 0.98).

PET foaming: development of a new class of rheological additives for improved processability Clizia Aversa, Massimiliano Barletta, Annalisa Genovesi, Annama