Objective: This study aimed to assess the impact of minimally invasive surgery (MIS) on survival rates in women diagnosed with endometrial cancer (EC). Methods: A retrospective cohort of 723 women who underwent MIS for EC was analyzed, with 468 having conventional laparoscopy (LPS) and 255 undergoing robotic-assisted laparoscopy (RAL). Sociodemographic features, tumor characteristics, and survival rates were examined for the entire cohort and in a propensity score-matched model. Results: In the overall sample, women who underwent RAL were older, had higher BMI, more comorbidities, and more aggressive tumors. After matching for age, BMI, comorbidities, ASA score, histological type, grade, myometrial invasion, LVSI, and FIGO stage, 482 patients (241 matched pairs) were selected. Disease-free survival (DFS) HR: 1, overall survival (OS) HR: 0.9, and specific survival related to EC (SS) HR: 0.15 were similar between the LPS and RAL groups. Conclusions: These findings suggest that the choice of surgical approach (robotic or laparoscopic) does not impact survival outcomes when matched in homogeneous groups.
8 November 2024 in Journal of Obstetrics and Gynaecology Research
Uterine cancer is the fourth most common cancer in women. Declining fertility, combined with increasing overweight and diabetes, might be some of the causes accountable for the rapid increase in the incidence of endometrial cancer (EC). Around 5% of EC are diagnosed in women aged under 40 years. We present a case of EC in a 36‐year‐old woman confirmed by hysteroscopy‐directed biopsy, who became pregnant before receiving any primary treatment. She had no other significant medical or family history of interest. Image staging found a uterine‐confined disease. The pregnancy had a normal course. The patient refused any type of treatment after delivery; thus, she was closely monitored every 3 months. No signs of disease recurrence were detected during the follow‐up. Pregnancy may be possible with early EC and it might an effective treatment for the disease in this case. The pregnancy acts as treatment and the gestation could continue until term without complications, in this patient diagnosed with EC.
23 January 2026 in International Journal of Gynecological Cancer