Even low-intensity blue light emitted by display devices exerts hazardous effects on RPE cells, which might be solved if display devices contain less short wavelength blue light.
1 May 2014 in Bioorganic & Medicinal Chemistry Letters
A concise and expeditious approach to the total synthesis of broussonone A, a p-quinol natural compound, has been developed. The key features of the synthesis include the Grubbs II catalyst mediated cross metathesis of two aromatic subunits, and a chemoselective oxidative dearomatizationin the presence of two phenol moieties. Especially, optimization associated with the CM reaction of ortho-alkoxystyrenes was also studied, which are known to be ineffective for Ru-catalyzed metathesis reactions under conventional reaction conditions because ortho-alkoxy group could coordinate to the ruthenium center, resulting in the potential complication of catalyst inhibition.
20 October 2011 in Bulletin of the Korean Chemical Society