Real-time simulation of a large-scale biologically representative spiking neural network is presented, through the use of a heterogeneous parallelization scheme and SpiNNaker neuromorphic hardware. A published cortical microcircuit model is used as a benchmark test case, representing ≈1 mm ² of early sensory cortex, containing 77 k neurons and 0.3 billion synapses. This is the first hard real-time simulation of this model, with 10 s of biological simulation time executed in 10 s wall-clock time. This surpasses best-published efforts on HPC neural simulators (3 × slowdown) and GPUs running optimized spiking neural network (SNN) libraries (2 × slowdown). Furthermore, the presented approach indicates that real-time processing can be maintained with increasing SNN size, breaking the communication barrier incurred by traditional computing machinery. Model results are compared to an established HPC simulator baseline to verify simulation correctness, comparing well across a range of statistical measures. Energy to solution and energy per synaptic event are also reported, demonstrating that the relatively low-tech SpiNNaker processors achieve a 10 × reduction in energy relative to modern HPC systems, and comparable energy consumption to modern GPUs. Finally, system robustness is demonstrated through multiple 12 h simulations of the cortical microcircuit, each simulating 12 h of biological time, and demonstrating the potential of neuromorphic hardware as a neuroscience research tool for studying complex spiking neural networks over extended time periods. This article is part of the theme issue ‘Harmonizing energy-autonomous computing and intelligence’.

Learning and development in real brains typically happens over long timescales, making long-term exploration of these features a significant research challenge. One way to address this problem is to use computational models to explore the brain, with Spiking Neural Networks a popular choice to capture neuron and synapse dynamics. However, researchers require simulation tools and platforms to execute simulations in real- or sub-realtime, to enable exploration of features such as long-term learning and neural pathologies over meaningful periods. This article presents novel multicore processing strategies on the SpiNNaker Neuromorphic hardware, addressing parallelization of Spiking Neural Network operations through allocation of dedicated computational units to specific tasks (such as neural and synaptic processing) to optimize performance. The work advances previous real-time simulations of a cortical microcircuit model, parameterizing load balancing between computational units in order to explore trade-offs between computational complexity and speed, to provide the best fit for a given application. By exploiting the flexibility of the SpiNNaker Neuromorphic platform, up to 9× throughput of neural operations is demonstrated when running biologically representative Spiking Neural Networks.

Neuroscience education is challenged by rapidly evolving technology and the development of interdisciplinary approaches for brain research. The Human Brain Project (HBP) Education Programme aimed to address the need for interdisciplinary expertise in brain research by equipping a new generation of researchers with skills across neuroscience, medicine, and information technology. Over its ten year duration, the programme engaged over 1,300 experts and attracted more than 5,500 participants from various scientific disciplines in its blended learning curriculum, specialised schools and workshops, and events fostering dialogue among early-career researchers. Key principles of the programme’s approach included fostering interdisciplinarity, adaptability to the evolving research landscape and infrastructure, and a collaborative environment with a focus on empowering early-career researchers. Following the programme’s conclusion, we provide here an analysis and in-depth view across a diverse range of educational formats and events. Our results show that the Education Programme achieved success in its wide geographic reach, the diversity of participants, and the establishment of transversal collaborations. Building on these experiences and achievements, we describe how leveraging digital tools and platforms provides accessible and highly specialised training, which can enhance existing education programmes for the next generation of brain researchers working in decentralised European collaborative spaces. Finally, we present the lessons learnt so that similar initiatives may improve upon our experience and incorporate our suggestions into their own programme.

The local circuitry of the mammalian brain is a focus of the search for generic computational principles because it is largely conserved across species and modalities. In 2014 a model was proposed representing all neurons and synapses of the stereotypical cortical microcircuit below 1 mm 2 of brain surface. The model reproduces fundamental features of brain activity but its impact remained limited because of its computational demands. For theory and simulation, however, the model was a breakthrough because it is full-scale, therefore free of uncertainties of downscaling, and larger models are less densely connected. This sparked a race in the neuromorphic computing community and the model became a de facto standard benchmark. Within a few years real-time performance was reached and surpassed at significantly reduced energy consumption. We review how the computational challenge was tackled by different simulation technologies and derive guidelines for the next generation of benchmarks and other domains of science.

This work presents a novel spiking neural network (SNN) decoding method, combining SNNs with hyperdimensional computing (HDC). This decoding method is designed to achieve high accuracy, high noise robustness, low inference latency and low energy consumption. Compared to analogous architectures decoded with existing approaches, the SNN-HDC model attains generally better classification accuracy, lower inference latency, lower spike count and lower estimated energy consumption on multiple test cases from the literature. The SNN-HDC achieved spike count reductions of 1.74 × to 3.36 × on the DvsGesture dataset and 1.36 × to 2.70 × on the SL-Animals-DVS dataset. The SNN-HDC achieved estimated energy consumption reductions of 1.24 × to 3.67 × on the DvsGesture dataset and 1.38 × to 2.27 × on the SL-Animals-DVS dataset. The proposed decoding method enables detection of classes unseen during training. On the DvsGesture dataset, the SNN-HDC model can detect 100% of samples from an unseen/untrained class. The findings suggest the proposed decoding method is a compelling alternative to both rate and latency decoding.

This paper provides an overview of the ongoing work to enable novel modalities of passive monocular neuromorphic vision in the NimbleAI sensing-processing architecture; namely, foveated and light-field event-driven vision with selective visual attention. The latter vision modality encodes 3D visual surroundings as sparse visual events in a 4D spatiotemporal domain, adding depth to current representation of visual information delivered by Dynamic Vision Sensors (DVS). The NimbleAI architecture implements hardware support for efficient execution of mainstream computer vision algorithms and AI models using these visual inputs. The architecture is designed to harness the latest advancements in 3D silicon integration, making it possible to squeeze sensing and spiking circuitry, memory, and processing engines into a miniature silicon volume.