Aim of study: To present the evolution of the current multi-objective Spanish National Forest Inventory (SNFI) through the assessment of different key indicators on challenging areas of the forestry sector.Area of study: Using information from the Second, Third and Fourth SNFI, this work provides case studies in Navarra, La Rioja, Galicia and Balearic Island regions and at national Spanish scale.Material and methods: These case studies present an estimation of reference values for dead wood by forest types, diameter-age modeling for Populus alba and Populus nigra in riparian forest, the invasiveness of alien species and the invasibility of forest types, herbivore preferences and effects on trees and shrub species, the methodology for estimating cork production , and the combination of SNFI4 information and Airborne Laser Scanning datasets with the aim of updating forest-fire behavior assessment information with a high degree of accuracy.Main results: The results show the suitability and feasibility of the proposed methodologies to estimate the indicators using SNFI data with the exception of the estimation of cork production. In this case, additional field variables were suggested in order to obtain robust estimates.Research highlights: By broadening the variables recorded, the SNFI has become an even more important source of forest information for the development of support tools for decision-making and assessment in diverse strategic fields such as those analyzed in this study.