To address the inefficiency and high cost of manual potato pickup in segmented harvesting, a dual-disc potato pickup and harvesting device was designed. The device utilizes counter-rotating dual discs to gather and preliminarily lift the potato–soil mixture, and combines it with an elevator chain to achieve potato–soil separation and transportation. Based on Hertz’s collision theory, the impact of disc rotational speed on potato damage was analyzed, establishing a maximum speed limit (≤62.56 r/min). Through kinematic analysis, the disc inclination angle (12–24°) and operational parameters were optimized. Through coupled EDEM-RecurDyn simulations and Box–Behnken experimental design, the optimal parameter combination was determined with the potato loss rate and potato damage rate as evaluation indices: disc rotational speed of 50 r/min, disc inclination angle of 16°, and machine forward speed of 0.6 m/s. Field validation tests revealed that the potato loss rate and potato damage rate were 1.53% and 2.45%, respectively, meeting the requirements of the DB64/T 1795-2021 standard. The research findings demonstrate that this device can efficiently replace manual potato picking, providing a reliable solution for the mechanized harvesting of potatoes.