Learning classifiers using skewed or imbalanced datasets can occasionally lead to classification issues; this is a serious issue. In some cases, one class contains the majority of examples while the other, which is frequently the more important class, is nevertheless represented by a smaller proportion of examples. Using this kind of data could make many carefully designed machine-learning systems ineffective. High training fidelity was a term used to describe biases vs. all other instances of the class. The best approach to all possible remedies to this issue is typically to gain from the minority class. The article examines the most widely used methods for addressing the problem of learning with a class imbalance, including data-level, algorithm-level, hybrid, cost-sensitive learning, and deep learning, etc. including their advantages and limitations. The efficiency and performance of the classifier are assessed using a myriad of evaluation metrics.

Erythemato-squamous diseases (ESD) diagnosis is a significant challenge in dermatology. It is divided into six categories. Artificial intelligence models have been applied to categorize these categories. Artificial intelligent models are black boxes in nature. The objective of this study is to unbox the black-box behavior and interpret the decision-making. Random Forest and XGBoost models are applied on a standard dataset with SHAP value to get interpretability and causability of decision. The Random Forest model had a classification accuracy of 98.21%. Integration of explainability increase the transparency of result and identify the root cause of the disease in the subject. A comprehensive quantitative study will help to adopt artificial intelligence in healthcare with ethical issues like transparency, causability, and interpretability of diagnosis.