Alexandra Mariana Buică

Dr. Alexandra Mariana Buică

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2024 in Children
Verified
Journal Article
Open access
PDF file
LALucia Emanuela Andrei
Lucia Emanuela Andrei
MBMagdalena Budisteanu
Magdalena Budisteanu
IMIlinca Mihailescu
Ilinca Mihailescu
ABAlexandra Mariana Buică
Alexandra Mariana Buică
MMMihaela Moise
Mihaela Moise
FRFlorina Rad
Florina Rad
Non-Suicidal Self-Injury (NSSI) involves deliberately causing harm to one’s body without the intention of suicide. As the numbers of adolescents presenting NSSI have been steadily increasing during the last years, we intended to investigate adolescent patients exhibiting NSSI, admitted to our clinic—a Romanian child psychiatry inpatient clinic, over the course of five years. A total of 100 adolescents (80 females, 20 males, mean age: 14.9 years) hospitalized for various neuropsychiatric disorders and engaging in self-harm were studied. The self-harm methods most frequently used in our sample were, for the female group: cutting (all), skin tearing (76%), scratching/pinching (72%), and for males: cutting (all), wound-healing hindrance (85%), striking objects (80%). The initial motivations for NSSI were represented by distress (females 89%, males 90%) and seeking pleasure (females 84%). In terms of the roles of NSSI, it was primarily used for emotional regulation (females 89%) and anger management (males 90%). This study highlights the prevalence of self-harm in hospitalized adolescents, differences in methods and motivations between genders, and the need for more targeted therapy interventions. By documenting trends, investigating underlying motivations and functions, and proposing hypotheses for further research, our findings offer valuable insights on adolescent NSSI and have the potential to increase awareness among various clinicians and specialists who interact with adolescents, thus addressing the escalating prevalence of self-harm behaviours among teenagers.

1 May 2020 in Rivista di Psichiatria
Verified
Journal Article
Closed access
FRFlorina Rad
Florina Rad
ABAlexandra Mariana Buică
Alexandra Mariana Buică
MSMihaela Stancu
Mihaela Stancu
AIAlecsandra Irimie-Ana
Alecsandra Irimie-Ana
EAEmanuela Andrei
Emanuela Andrei
IDIuliana Dobrescu
Iuliana Dobrescu
SUMMARY. Background . Attention Deficit Hyperactivity Disorder (ADHD) has a high degree of heritability and recently has become a challenge not only for clinicians evaluating children and adolescents but also for adult psychiatrists. The latest studies and diagnostic manuals show that the ADHD symptoms are not “overgrown” in adulthood, the way they are expressed merely changes. Methods. The present study investigates the presence of ADHD symptoms in a group of 104 adult patients admitted to psychiatric services, with chronic substance abuse. The subjects selected for the study were evaluated using the DIVA 2.0 instrument, a scale designed to diagnose ADHD in adulthood. Results. The study results showed that 46% of the drug users, included in the study, have specific symptoms that can be diagnosed as ADHD in adults. Of the 54 subjects who met ADHD criteria in childhood, only 6 did not meet these criteria in adult life, resulting in 89% of ADHD patients maintaining symptoms in adulthood, causing dysfunction in certain life areas. Conclusions. The presence of ADHD diagnosis in the selected group, has been shown to increase the vulnerability of up to twice the chronic consumption of psychostimulants, an observation of great therapeutic and prophylactic importance for clinical practice. The research also confirms the fact revealed in the latest data from the international literature regarding the consumption of psychoactive substances from young ages, with multiple comorbidities and recurrent behavioral disorders secondary to drug use and major difficulties in following the recommendations of treatment and to get the remission that put their mark on the failure of education and personal development.

26 August 2022 in Medicine
Verified
Journal Article
Open access
FRFlorina Rad
Florina Rad
MMMihaela Moise
Mihaela Moise
LALucia-Emanuela Andrei
Lucia-Emanuela Andrei
FLFlorentina Ionela Linca
Florentina Ionela Linca
ABAlexandra Mariana Buică
Alexandra Mariana Buică
MBMagdalena Budisteanu
Magdalena Budisteanu
Studies on early onset schizophrenia are limited because of their low prevalence but the reported results stated that early onset is associated with a poorer outcome. The present research analyzed the stability rate of the psychotic-related disorders from childhood to adult life. The study was based on an observational, retrospective, descriptive analysis study. The subjects were selected from patients admitted to the pediatric psychiatry ward of “Alexandru Obregia” Psychiatry Hospital between 2009 and 2018 for a psychosis-related disorder, who were 18 years or older at the moment of data collection and who also had admissions into the adult’s psychiatry wards of the hospital. Of the 115 subjects, 93, representing 80.87% of the total, maintained a diagnosis of psychotic spectrum disorder into adulthood. The diagnosis was maintained in 82.4% of cases with onset before 13 years old and 80.6% of cases with onset after the age of 13 years of age. Of the 42 subjects who presented affective symptoms during childhood, 71.43% also presented affective symptoms into adulthood. These findings indicate an important stability rate of psychosis from childhood and adulthood and come in accordance with the theory of overlap between psychotic and affective disorders. The results underline the importance of an accurate diagnosis of early and very early onset schizophrenia (VEOS), the need for early and multimodal intervention, but also the need for long-term management of these patients and continuing research regarding psychotic-related disorders in children and adolescents.

29 November 2023 in Children
Verified
Journal Article
Open access
PDF file
IMIlinca Mihailescu
Ilinca Mihailescu
MBMagdalena Budisteanu
Magdalena Budisteanu
LALucia Emanuela Andrei
Lucia Emanuela Andrei
ABAlexandra Mariana Buică
Alexandra Mariana Buică
MMMihaela Moise
Mihaela Moise
FRFlorina Rad
Florina Rad
The aim of the present study is to describe and measure the cognitive emotion regulation strategies of inpatient adolescents with clinical depression, aged 13–18, and to analyse these coping strategies in relation to different comorbidities of Major Depressive Disorder (MDD). Methods: There were 112 adolescents with MDD who were admitted to hospital and 78 healthy adolescents included in the study. The Cognitive Emotion Regulation Questionnaire (CERQ) was used to assess nine specific cognitive coping strategies. A cognitive coping style model for depression in adolescents was described by analysing the differences between the two groups. The CERQ scores in MDD participants, grouped by comorbidity, were also assessed. Results: Adolescents with MDD had significantly higher scores for Self-Blame and Catastrophising strategies, and significantly lower scores for Positive Refocusing, Refocusing on Planning, and Positive Reappraisal. Adolescents with MDD and Borderline Personality Disorder (BPD) traits had significantly higher scores for Rumination, Catastrophising, and Blaming Others than adolescents with MDD and anxiety or with no comorbidity. Conclusions: Clinical depression in adolescents is associated with a cognitive profile that consists of an increased use of maladaptive coping styles and low employment of adaptive strategies. Early identification can contribute to the development of specific, individualised prevention and intervention programmes, while further longitudinal studies are necessary to adequately measure the outcome of these interventions.

7 January 2025 in Children
Verified
Journal Article
Open access
PDF file
FRFlorina Rad
Florina Rad
ABAlexandra Mariana Buică
Alexandra Mariana Buică
Nicolae GicaNicolae Gica
Nicolae Gica
Background/Objectives: Although ADHD in adults has become visible and inclusive in recent years in diagnostic manuals, research is still limited regarding the long-term outcomes of patients with this disorder. The main objective of this research was to address the many facets of predictor variables in girls with ADHD facing unplanned pregnancies at young ages in order to improve the management of pre-, peri-, and postnatal complications that may occur, as well as for early psychiatric diagnosis and effective intervention. Methods: PubMed and Web of Science Databases were used to perform literature research, and a total of 27 records were selected and used for data extraction. Results: Related articles have included the persistence of ADHD symptoms comorbid with other disorders among girls with ADHD as a risk factor for teenage pregnancies. Conduct disorders and substance use disorders are the main co-occurrent diagnoses that increase the likelihood for teenage childbirth. Unplanned pregnancies at young ages are associated with unfavorable psychosocial trajectories both for the mother and the child. Conclusions: In this review, we emphasize the importance of predisposing factors for risky sexual behaviors and unplanned pregnancies in cases of girls with ADHD. The topic of the article draws attention to the need for uniform national individualized care of girls with ADHD, the implementation of programs to prevent academic failure and early parenthood as well as addressing comorbid obstetrical and psychiatric conditions, especially in regions where the rate of adolescent births continues to be high.

1 January 2019 in Rivista di Psichiatria
Verified
Journal Article
Closed access
FRFlorina Rad
Florina Rad
ABAlexandra Mariana Buică
Alexandra Mariana Buică
GAGianina Cristina Anghel
Gianina Cristina Anghel
MSMihaela Stancu
Mihaela Stancu
IDIuliana Dobrescu
Iuliana Dobrescu
SUMMARY. In this paper we present the case of a female teenager patient who was diagnosed with bipolar affective disorder and during psychotropic treatment with risperidone, the prolactin levels ranged between 55 ng/mL and 85 ng/mL at monthly repeated dosing. During this period, the patient presented somatic alterations in her state of health. The patient benefited from brain imaging, which revealed that in sella turcica is distinguished a well-defined and relatively homogeneous formation, measuring approximately 11/8 mm, suggestive of a pituitary adenoma. After changing the antipsychotic treatment, the pituitary formation resolved to a subsequent imaging re-evaluation.