Background: Although noninvasive brain stimulation (NIBS) techniques are an effective alternative treatment option, their relative effects in patients with Parkinson’s disease (PD) remain undefined. Here, we aimed to compare motor efficacy of the NIBS techniques in PD. Methods: We carried out an electronic search in PubMed, Embase, Cochrane Library, CINAHL, PEDro and PsycINFO (accessed via Ovid) for articles published until August 2022. The treatment efficacy of motor function was quantified by the Unified Parkinson’s disease rating scale part III. Results: 28 randomized controlled trials with parallel group were included in the analysis, enrolling 1057 patients. In the “on” state, high-frequency repetitive transcranial magnetic stimulation (HFrTMS) conferred better short-term and long-term efficacy compared to transcranial direct current stimulation. Surface under the cumulative ranking curve rank showed that HFrTMS combined with transcranial direct current stimulation and low-frequency TMS ranked first among PD in improving motor function. In the “off” state, there were no significant differences in most of the treatments, but surface under the cumulative ranking curve rank showed that continuous theta burst stimulation and low-frequency TMS had the highest short- and long-term effect in improving motor function. Conclusion: HFrTMS is an effective intervention in improving motor function. Besides, its combination with another NIBS technique produces better therapeutic effects in the “on” state.
Runners have a high probability of sports injuries due to improper landing patterns. This study aimed to investigate the effects of three different foot strike patterns on lower limb muscle activation in healthy young male university students without specialized sports training experience. Methods: Sixteen healthy male college students (age: 21 ± 1 years) participated in this study. They performed running with three different foot strike patterns: forefoot strike (FFS), midfoot strike (MFS), and rearfoot strike (RFS) at controlled speeds of 1.4–1.6 m/s. EMG signals from six lower limb muscles (vastus lateralis, vastus medialis, rectus femoris, tibialis anterior, lateral gastrocnemius, and medial gastrocnemius) during the stance phase were collected using a wireless EMG system (1000 Hz). Ensemble Empirical Mode Decomposition (EEMD) was employed to analyze the time–frequency characteristics of lower limb EMG signals and ankle joint co-activation patterns to investigate the corresponding neuromuscular control mechanisms. Statistical analyses were performed using repeated-measures ANOVA, and significance was set at p < 0.05. Results: The timing of maximum energy in lower limb muscles during the stance phase occurred earlier in RFS compared to FFS and MFS. At initial ground contact, the low-frequency component energy (below 60 Hz) of the medial gastrocnemius was significantly higher in MFS and RFS compared to FFS, while FFS exhibited significantly higher high-frequency component energy (61–200 Hz). The co-activation of ankle dorsiflexors and plantar flexors (TA/GM) was also significantly higher in MFS and RFS compared to FFS. During the 100 ms before foot contact, the low-frequency component energy (below 60 Hz) of the lateral gastrocnemius was significantly higher in MFS compared to FFS, and the degree of TA/GM co-activation was significantly higher in both MFS and RFS compared to FFS. Conclusions: The maximum frequency in lower limb muscles appeared earliest during the mid-stance phase in the rearfoot strike (RFS) pattern. Moreover, during the pre-activation and early stance phases, frequency differences were observed only in the medial gastrocnemius, with RFS showing significantly higher low-frequency power.
Background: This study investigates the differences in limb coordination patterns and energy transfer strategies during sit-to-stand (STS) transitions among young adults (18–30 years) with overweight (OW), normal weight (NW), and underweight (UW) conditions, providing a theoretical foundation for understanding the impact of BMI variations on movement control mechanisms and informing health intervention strategies. Methods: Forty participants were classified into OW, NW, and UW groups. Motion data were collected via an infrared motion capture system and force plate. Biomechanical indices were computed using Visual 3D and MATLAB2020a. Coordination patterns were assessed using vector coding, and the segmental net power was analyzed to evaluate energy flow during STS. Statistical analyses were performed using one-way ANOVA (α = 0.05). Results: Compared to the NW and UW groups, the OW group exhibited significant differences in movement coordination patterns and energy flow. In terms of coordination patterns, the OW group adopted more hip-knee distal coordination patterns in the FMP phase and more knee-ankle proximal coordination patterns. In the MTP phase, the OW group exhibited a lower frequency of hip-ankle anti-phase coordination patterns compared to the UW group. In the EP phase, the OW group showed a lower frequency of trunk-pelvis proximal coordination patterns than the UW group (p < 0.05). Regarding energy flow, in the FMP phase, the OW group exhibited higher joint power (JP) and segment power (SP) in the trunk compared to the UW group. In the pelvic segment, both JP and SP were higher in the OW group than in the NW and UW groups. In the thigh segment, muscle power (MP) was higher in the OW group than in the NW and UW groups, and SP was higher than in the NW group (p < 0.05). Conclusion: Changes in BMI affect movement coordination and energy transfer strategies during STS. OW individuals compensate for insufficient hip drive by relying on trunk and pelvic power, which may increase the knee and trunk load over time. In contrast, UW individuals exhibit greater lower-limb flexibility and rely on trunk-pelvis coordination to compensate for stability deficits. Future research should develop targeted exercise interventions to optimize movement patterns and reduce injury risk across BMI groups.
Background: This study investigated sex differences in foot arch structure and function, and their impact on postural control and energy flow during dynamic tasks. Findings aim to inform sex-specific training, movement assessment, and injury prevention strategies. Methods: A total of 108 participants (53 males and 55 females) underwent foot arch morphological assessments and performed a sit-to-stand (STS). Motion data were collected using an infrared motion capture system, three-dimensional force plates, and wireless surface electromyography. A rigid body model was constructed in Visual3D, and joint forces, segmental angular and linear velocities, center of pressure (COP), and center of mass (COM) were calculated using MATLAB. Segmental net energy was integrated to determine energy flow across different phases of the STS. Results: Arch stiffness was significantly higher in males. In terms of postural control, males exhibited significantly lower mediolateral COP frequency and anteroposterior COM peak velocity during the pre-seat-off phase, and lower COM displacement, peak velocity, and sample entropy during the post-seat-off phase compared to females. Conversely, males showed higher anteroposterior COM velocity before seat-off, and greater anteroposterior and vertical momentum after seat-off (p < 0.05). Regarding energy flow, males exhibited higher thigh muscle power, segmental net power during both phases, and greater shank joint power before seat-off. In contrast, females showed higher thigh joint power before seat-off and greater shank joint power after seat-off (p < 0.05). Conclusions: Significant sex differences in foot arch function influence postural control and energy transfer during STS. Compared to males, females rely on more frequent postural adjustments to compensate for lower arch stiffness, which may increase mechanical loading on the knee and ankle and elevate injury risk.
Objective: The objective of this study was to explore the motion characteristics and movement strategies of the hip and knee joints in overweight individuals during sit-to-stand (STS) transfers using statistical parametric mapping (SPM). Methods: Twenty subjects were divided into an overweight group (n = 10) and a normal-weight group (n = 10) based on body mass index (BMI). The Qualisys infrared motion capture system and Kistler three-dimensional force platform were used for motion data collection, and Visual 3D and Matlab were used to calculate the angles and torque indicators of the lower limb hip and knee joints. Results: During the STS process, the maximum hip flexion angle of the overweight group was smaller than that of the control group (Z = −1.83, p = 0.043, r = 0.39), while the maximum abduction and external rotation angles were greater than those of the control group (Z = −2.15, p = 0.022, r = 0.46; Z = −2.02, p = 0.028, r = 0.48). SPM analysis showed that during the 0–52% phase of the hip joint in the frontal plane, the abduction amplitude of the overweight population was greater than that of the normal population (p < 0.05). The minimum external rotation angle of the knee joint was less than that of the control group (F(1,18) = 9.135, p = 0.043). The peak internal adduction and abduction torque of the hip joint in the overweight group was greater than that of the control group (Z = 2.37, p = 0.017, r = 0.54). Conclusions: Compared with the normal-weight population, the overweight population exhibited distinct motion characteristics of the hip and knee joints during the STS, with particularly pronounced differences in the hip joint. To maintain stability during STS, the overweight population adopts a compensatory movement strategy featuring a wider base of support via hip abduction and increased muscular torque to control frontal plane stability, which imposes greater functional loads on the hip joint. BMI-related movement characteristics should be studied in young adults under controlled experimental conditions, and future studies are needed to verify whether similar patterns exist in older adults.