Congenital limb defects occur when a limb does not develop normally during pregnancy. The quality of each person's everyday life is significantly impacted by any of these defects and there is no concrete treatment. 3D modeling and printing, enables the creation and customization of precise virtual and/or physical models, including models of the human anatomy. These technologies provide a novel method of producing new devices with optimized design and production time, improving adaptability, and incorporating functionality. To this end, we propose a method of designing and producing 3D printed assistive devices and we also present an example of an assistive device, done in the 3D Printing Center for Health, as well as its impact on the patient's daily life. With this device, the patient became able to play the guitar and hold a knife, thus helping on these two activities.

The pupil shows a fast dynamical adaptation to external light changes, in order to potentiate visual perception. It contracts in high luminosity environments, so as to limit the quantity of photons that reach the retina (miosis) and dilates in environments with little luminosity, thus increasing the number of photons in the retina (mydriasis). Hence, the pupil acts as a normalizer of the quantity of light that enters the optical system. These pupillary movements are controlled by the action of smooth muscles, which are associated with the sympathetic (SNS) and parasympathetic autonomous nervous systems (PsNS). Therefore, the study of the pupillary dynamics can lead to inferences on the functioning of those two antagonist systems and their involvement in pupillary control. In addition, our study may prove clinically helpful in determining a patient's level of consciousness, as well as identifying certain diseases, such as sleep disorders, photophobia, schizophrenia, Adie syndrome, Alzheimer's and Parkinson's disease. With a clear goal in its clinical applications, we focus our research in the identification of the frequency intervals pertaining to the action of the autonomous nervous system, as well as their individual sympathetic and parasympathetic roles. We analyze high-resolution, non-invasive pupillometric signals, both in a basal condition and as a response to visual flashes or to the application of a cold stimulus. We use Singular Spectrum Analysis (SSA) to identify the frequencies of interest related to the actions of the SNS and PsNS. In addition, and as a complementary means of frequency analysis, we also use the more classical wavelets analysis. We find out that SSA is an ideal tool for the identification of the desired frequencies in stake. The agreement between the outcomes of both analyses supports our conclusions regarding the autonomous nervous system. (C) 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).Peer reviewe