(1) Background: In the older population, depression often affects people with chronic medical illnesses, cognitive impairment, or disability. Frailty is another important issue affecting older adults, being difficult to clinically distinguish from frailty in advanced old age. Well-designed interventional studies and clinical strategies targeting both frailty and depression are rare or nonexistent. (2) Methods: We realized a retrospective study in which we included a total of 411 patients that were admitted to the Geriatric Clinic from “Dr. C. I. Parhon” Hospital from Iasi for a period of 13 months. The aim of our study was to investigate the relationship between depression and frailty in a geriatric population due to the fact that the quality of life is negatively influenced by both frailty and depression. (3) Results: The prevalence of the depressive symptoms screened by the GDS-15 was 66.7%, with women being more depressed than men. Furthermore, an obvious relationship between depression and the dependence degree in performing daily activities has been observed. In addition, the mean MMSE score decreased with an increasing degree of depression. (4) Conclusions: Our study demonstrates the association between frailty and depression, one of them being a risk factor in the development of the other. A poor acknowledgment of the problem and an underdiagnosis of these conditions are important public health concerns due to the high healthcare costs. Thus, an active primary prevention would be imperiously needed in order to diagnose frailty and depression at an early stage, increasing the quality of life of the elderly and also their successful aging.

Hip fractures in elderly patients pose significant clinical challenges, confronting us with high morbidity and mortality rates. A comprehensive geriatric assessment plays an important role in determining prognosis as well as the indication for surgery. Aim: In this study, we aim to (1) assess frailty-based functional status in seniors with hip fractures, (2) evaluate geriatric assessment’s predictive value for postoperative recovery, and (3) analyze 1-year postoperative survival. Material and Methods: This prospective study included 60 senior patients admitted for hip fracture in the Orthopedics Department. Patients were examined using geriatric assessment instruments Mini Mental State Examination (MMSE), Geriatric Depression Scale (GDS), Mini Nutritional Assessment (MNA), and Frailty Groningen Indicator (GFI). We recorded the sex, marital status, number of comorbidities, and number of recommended drugs. Results: In total, 65% of patients were frail pre-surgery; the proportion increased post-surgery to 86.7%; (p = 0.005). Age greater than 80 years and unmarried marital status were associated with higher frailty risk (p = 0.04; p = 0.03). Preoperatively, important predictors of frailty were mild–moderate cognitive impairment (p = 0.017), mild–moderate depression (p = 0.01), and malnutrition (p = 0.04). Postoperatively, only mild–moderate cognitive impairment (p = 0.04) and mild–moderate depression (p = 0.01) proved to be important predictors of frailty. According to the ROC curve, good predictors of postoperative frailty were shown to be preoperative frailty and the degree of polypharmacy and comorbidity. Of all parameters predictive of postoperative frailty, only the number of medications reached statistical significance (p < 0.038). The study identified a 1-year all-cause mortality rate of 42.6% in elderly patients who underwent hip fracture surgery, with a significant association between mortality and preoperative MMSE, GDS, and MNA scores. Conclusions: Complex geriatric assessment of senior patients with hip fracture can stratify postoperative risk and predict 1-year mortality and postoperative functional recovery. Key predictors include cognitive status, depression, malnutrition, and comorbidities. Multidisciplinary care and standardized evaluation are essential for improving outcomes.

Background and Objectives: Burnout syndrome is a major challenge among healthcare workers, affecting both mental and physical health. Although stress may influence physiological systems, this study does not directly assess biological mechanisms, and interpretations should remain associative. Stress-related associations may be reflected in body composition, but objective data are limited. This study aims to assess the associations between burnout, body composition, and quality of life in medical staff, using bioimpedance as the main tool. Material and methods: The cross-sectional study included 95 medical staff (36 resident doctors, 13 specialists/consultants, 31 nurses, 15 nursing assistants), 75.8% women, mean age 38 ± 10 years, conducted in the medical and surgical departments of Dr. C.I. Parhon Clinical Hospital, Iași, between January and March 2024. Burnout was assessed using the Maslach Burnout Inventory; quality of life was evaluated with SF-12; body composition was measured by bioimpedance (BMI, muscle mass, fat mass, bone mass, hydration, basal metabolism, metabolic age). Statistical analyses included ANOVA, Kruskal–Wallis, and Spearman correlations. Results: Resident physicians had higher muscle, bone mass and basal metabolism, with lower adipose tissue compared to other categories (p < 0.05). Total burnout and exhaustion were positively correlated with muscle mass (r = 0.247, p = 0.016), bone mass (r = 0.219, p = 0.033), basal metabolism (r = 0.219, p = 0.033) and negatively with QoLM (r = −0.315, p = 0.002). Other body variables, including BMI, total adipose tissue, and water level, showed no significant correlations. These associations may be influenced by age, sex, and professional category and do not imply causality. Conclusions: Age, profession, and work seniority are associated with burnout and specific changes in body composition. However, these findings are correlational, and bioimpedance-derived parameters do not reflect direct biological stress mechanisms.