As the epidemic affected everyone across the world, the solution to the epidemic was developed globally. Many applications adopt Internet of Things (IoT) technology to detect epidemics, and effective monitoring systems are developed to monitor air pollution, personal transmission, early detection of serious cases, and remote assessment. However, care facilities in an aging society require effective disinfection and sterilization to prevent viral transmission. We integrated the interactive and real-time features of the Internet of Things (IoT) to design and build an intelligent self-propelled sterilization robot for sterilization. Intelligent sterilization and disinfection planning and task allocation mechanisms were designed for sterilization in clinics. For healthcare facilities, the developed robot can reduce the burden on healthcare professionals, help to manage the disinfection and sterilization process, and ensure patient safety. At the same time, robots promote the development of epidemic prevention industries and prepares for future attacks from harmful air pollutants or new infections.