Diphtheria is a severely infectious and deadly bacterial disease with Corynebacterium diphtheriae as the causative agent. Since the COVID-19 pandemic, contagious diseases such as diphtheria have re-emerged due to disruptions in routine childhood immunization programs worldwide. Nigeria is witnessing a significant increase in diphtheria outbreaks likely due to an inadequate health care system and insufficient public enlightenment campaign. This paper presents a mathematical epidemic diphtheria model in Nigeria, which includes a public enlightenment campaign to assess its positive impact on the prevalence of the disease. The mathematical analysis of the model reveals two equilibrium points: the diphtheria infection-free equilibrium and the endemic equilibrium. These equilibrium points are shown to be stable globally asymptotically if and , respectively. The model was fit using the confirmed diphtheria cases data of Kano State from January to December 2023. Sensitivity analysis indicates that the transmission rate and recovery rate of asymptomatic peopleare crucial parameters to be considered in developing effective strategies for diphtheria control and prevention. This analysis also reveals that the implementation of a high-level public enlightenment campaign and its high efficacy effectively reduce the prevalence of diphtheria. Finally, numerical simulations show that combining the public enlightenment campaign and isolating infected individuals is the best strategy to contain the spread of diphtheria.
7 March 2024 in Pakistan Journal of Statistics and Operation Research
This article introduces a new three-parameter lifetime model with an increasing and bathtub failure rate functions as an extension of the Mustapha type II distribution (MuII). The model can be very useful in statistical studies, reliability, computer sciences and engineering. Various mathematical and statistical properties of the distribution are discussed, such as moments, mean deviations, Bonferroni and Lorenz curves, entropy, order statistic, and extreme value distributions. Moreover, we consider the bivariate extension of the new model. Statistical inferences by the maximum likelihood method are discussed and assess by simulation studies. Applications of the proposed model to two right-skewed data are presented for illustration. The new model provides a better fit than some other existing distribution as measured by some model selection criteria and goodness of fits statistics.