The uterus is the most important organ in the female reproductive system. Its shape plays a critical role in fertility and pregnancy outcomes. Advances in medical imaging, such as 3D ultrasound, have significantly improved the exploration of the female genital tract, thereby enhancing gynecological healthcare. Despite well-documented data for organs like the liver and heart, large-scale studies on the uterus are lacking. Existing classifications, such as VCUAM and ESHRE/ESGE, provide different definitions for normal uterine shapes but are not based on real-world measurements. Moreover, the lack of comprehensive datasets significantly hinders research in this area. Our research, part of the larger NURSE study, aims to fill this gap by establishing the shape of a normal uterus using real-world 3D vaginal ultrasound scans. This will facilitate research into uterine shape abnormalities associated with infertility and recurrent miscarriages. We developed an automated system for the segmentation and alignment of uterine shapes from 3D ultrasound data, which consists of two steps: automatic segmentation of the uteri in 3D ultrasound scans using deep learning techniques, and alignment of the resulting shapes with standard geometrical approaches, enabling the extraction of the normal shape for future analysis. The system was trained and validated on a comprehensive dataset of 3D ultrasound images from multiple medical centers. Its performance was evaluated by comparing the automated results with manual annotations provided by expert clinicians. The presented approach demonstrated high accuracy in segmenting and aligning uterine shapes from 3D ultrasound data. The segmentation achieved an average Dice similarity coefficient (DSC) of 0.90. Our method for aligning uterine shapes showed minimal translation and rotation errors compared to traditional methods, with the preliminary average shape exhibiting characteristics consistent with expert findings of a normal uterus. We have presented an approach to automatically segment and align uterine shapes from 3D ultrasound data. We trained a deep learning nnU-Net model that achieved high accuracy and proposed an alignment method using a combination of standard geometrical techniques. Additionally, we have created a publicly available dataset of 3D transvaginal ultrasound volumes with manual annotations of uterine cavities to support further research and development in this field. The dataset and the trained models are available at https://github.com/UL-FRI-LGM/UterUS.

We present a combined volume and surface rendering technique with global illumination caching. Our approach uses volumetric path tracing to compute the global illumination volume and local shading models for rendering the isosurface. By joining both visualization approaches, we have enhanced the display and illumination of the surfaces while preserving physically realistic illumination of the participating media. To achieve real-time performance and avoid recomputing the image when the camera view changes, we compute the global illumination volume incrementally and defer the projection to a later step. We evaluated our technique by comparing different local shading models for isosurface rendering with the result of full volumetric path tracing and with the non-caching variant of our technique. Results show that the caching and non-caching variants perform comparably well, while the caching variant has the added benefit of being camera-view-independent. Additionally, we show that our approach emphasizes the surfaces within volumes better than volumetric path tracing.

We present a novel smart visibility system for visualizing crowded volumetric data containing many object instances. The presented approach allows users to form groups of objects through membership predicates and to individually control the visibility of the instances in each group. Unlike previous smart visibility approaches, our approach controls the visibility on a per-instance basis and decides which instances are displayed or hidden based on the membership predicates and the current view. Thus, cluttered and dense volumes that are notoriously difficult to explore effectively are automatically sparsified so that the essential information is extracted and presented to the user. The proposed system is generic and can be easily integrated into existing volume rendering applications and applied to many different domains. We demonstrate the use of the volume conductor for visualizing fiber-reinforced polymers and intracellular organelle structures.

Self-regulated learning (SRL) plays an important role in successful learning with hypertexts. The use of appropriate SRL strategies helps students acquire new knowledge more efficiently. We investigated the use of SRL strategies in individual learning from expository science hypertext, the correlations between different measures of self-regulation, and the differences in SRL between more and less successful students. A sample of 443 ninth graders from 15 different schools participated in the study. A variety of off- and online measures were used to measure SRL. Data were collected from student traces, questionnaires, tests scores, and notes. Low correlations between the off- and online measures of SRL suggest that they measure different aspects of SRL use in learning digital science texts. Student achievement in science positively correlated with their use of SRL strategies. Students with higher knowledge gains reported the higher use of deep cognitive strategies, higher motivation for learning, and used a higher number of strategies in note-taking while learning. The results of this study may have practical implications for teachers to support student SRL and for developers of digital learning materials to incorporate SRL scaffolding into learning topics.

Depth perception in volumetric visualization plays a crucial role in the understanding and interpretation of volumetric data. Numerous visualization techniques, many of which rely on physically based optical effects, promise to improve depth perception but often do so without considering camera movement or the content of the volume. As a result, the findings from previous studies may not be directly applicable to crowded volumes, where a large number of contained structures disrupts spatial perception. Crowded volumes therefore require special analysis and visualization tools with sparsification capabilities. Interactivity is an integral part of visualizing and exploring crowded volumes, but has received little attention in previous studies. To address this gap, we conducted a study to assess the impact of different rendering techniques on depth perception in crowded volumes, with a particular focus on the effects of camera movement. The results show that depth perception considering camera motion depends much more on the content of the volume than on the chosen visualization technique. Furthermore, we found that conventional non-photorealistic rendering techniques, which have often performed poorly in previous studies, showed comparable performance to modern photorealistic techniques in our study. The source code for the visualization system, survey, and analysis, as well as the data set used in the study and the participants’ responses, have been made publicly available.