Alexandra Stefania Mihai

Mrs. Alexandra Stefania Mihai

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 May 2025 in Sensors
Verified
Journal Article
Open access
PDF file
AMAlexandra Stefania Mihai
Alexandra Stefania Mihai
AMAlexandra Stefania Mihai
Alexandra Stefania Mihai
Oana GEMANOana GEMAN
Oana GEMAN
RTRoxana Toderean
Roxana Toderean
LMLucas Miron
Lucas Miron
SSSara SharghiLavan
Sara SharghiLavan
Electroencephalography (EEG) remains an essential method for monitoring brain activity, but the limitations of conventional systems due to the complexity of installation and lack of portability have led to the introduction and development of in-ear EEG technology. In-ear EEG is an emerging method of recording electrical activity in the brain and is an innovative concept that offers multiple advantages both from the point of view of the device itself, which is easily portable, and from the user’s point of view, who is more comfortable with it, even in long-term use. One of the fundamental components of this type of device is the electrodes used to capture the EEG signal. This innovative method allows bioelectrical signals to be captured through electrodes integrated into an earpiece, offering significant advantages in terms of comfort, portability, and accessibility. Recent studies have demonstrated that in-ear EEG can record signals qualitatively comparable to scalp EEG, with an optimized signal-to-noise ratio and improved electrode stability. Furthermore, this review provides a comparative synthesis of performance parameters such as signal-to-noise ratio (SNR), common-mode rejection ratio (CMRR), signal amplitude, and comfort, highlighting the strengths and limitations of in-ear EEG systems relative to conventional scalp EEG. This study also introduces a visual model outlining the stages of technological development for in-ear EEG, from initial research to clinical and commercial deployment. Particular attention is given to current innovations in electrode materials and design strategies aimed at balancing biocompatibility, signal fidelity, and anatomical adaptability. This article analyzes the evolution of EEG in the ear, briefly presents the comparative aspects of EEG—EEG in the ear from the perspective of the electrodes used, highlighting the advantages and challenges of using this new technology. It also discusses aspects related to the electrodes used in EEG in the ear: types of electrodes used in EEG in the ear, improvement of contact impedance, and adaptability to the anatomical variability of the ear canal. A comparative analysis of electrode performance in terms of signal quality, long-term stability, and compatibility with use in daily life was also performed. The integration of intra-auricular EEG in wearable devices opens new perspectives for clinical applications, including sleep monitoring, epilepsy diagnosis, and brain–computer interfaces. This study highlights the challenges and prospects in the development of in-ear EEG electrodes, with a focus on integration into wearable devices and the use of biocompatible materials to improve durability and enhance user comfort. Despite its considerable potential, the widespread deployment of in-ear EEG faces challenges such as anatomical variability of the ear canal, optimization of ergonomics, and reduction in motion artifacts. Future research aims to improve device design for long-term monitoring, integrate advanced signal processing algorithms, and explore applications in neurorehabilitation and early diagnosis of neurodegenerative diseases.

1 May 2026
Verified
Book Chapter
Closed access
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AMAlexandra Stefania Mihai
Alexandra Stefania Mihai
Liliana VerestiucLiliana Verestiuc
Liliana Verestiuc
INIsabella Nacu
Isabella Nacu
Oana GEMANOana GEMAN
Oana GEMAN

8 May 2026 in Sensors
Verified
Journal Article
Open access
PDF file
AMAlexandra Stefania Mihai
Alexandra Stefania Mihai
AIAna-Maria Iordache
Ana-Maria Iordache
Liliana VerestiucLiliana Verestiuc
Liliana Verestiuc
INIsabella Nacu
Isabella Nacu
Oana GEMANOana GEMAN
Oana GEMAN
Electrical monitoring of brain activity can be performed discreetly and continuously over long periods of time using intra-auricular electroencephalography (intra-auricular EEG), a promising technique suitable for subjects who are difficult to monitor, such as newborns or patients with neurological conditions requiring discreet but long-term neurophysiological assessment. The concept of intra-aural EEG can be realized through the development of systems that include wearable sensors, whose performance critically depends on the development of biocompatible electrode materials that exhibit low impedance and can maintain and provide stable contact between the electrode and the epithelial tissue. Based on our previous work on carbon nanotube (CNT)-based hydrogel composites for intra-aural EEG electrodes, this study focuses on the electrochemical characterization of hydrogels initially prepared from gelatin methacrylate (GelMA)/2-hydroxyethyl methacrylate (HEMA) doped with varying concentrations of CNTs (0–3 wt%). In the present study, the materials obtained in the first stage were evaluated using electrochemical impedance spectroscopy (EIS) under both liquid and dry conditions, supplemented by measurements of hydration capacity. The results show that the composite with 3% CNT content exhibits suitable properties, making the material making the 3 wt% CNT formulation a promising platform for the further development of 3D-printable hydrogel electrodes for intra-aural EEG applications. Equivalent circuit modeling reveals improved ionic and electronic conductivity compared to the undoped hydrogel, attributed to better CNT dispersion and polymer crosslinking. This work provides insights into the structure–property relationships of CNT–hydrogel composites and lays the foundation for the further development of a 3D-printed and in vitro/in vivo validated prototype of intra-aural EEG sensors.

9 July 2026 in Engineering Proceedings
Verified
Conference Paper
Open access
PDF file
LMLucas Miron
Lucas Miron
Oana GEMANOana GEMAN
Oana GEMAN
AMAlexandra Stefania Mihai
Alexandra Stefania Mihai
RTRoxana Toderean
Roxana Toderean
This paper describes the development and testing of a portable in-ear electroencephalography (EEG) system that uses dry electrodes made from different materials. Brain signals were collected from electrodes placed inside the ear and around the ear and were compared with signals recorded using standard scalp EEG systems. The results indicate that EEG signals recorded from the ear show a clear correlation with those obtained from scalp electrodes. At the same time, the in-ear system provides better user comfort, fewer movement-related artifacts, and a more discreet form factor. Even though the signal-to-noise ratio is slightly lower than in conventional EEG systems, the device remains suitable for portable and long-term recordings. These findings confirm that in-ear-EEG technology is a viable solution for applications in audiology, neuroscience, clinical brain monitoring, and brain–computer interface systems.

16 February 2026 in bioRxiv
Verified
Preprint
Open access
PDF file
Oana GEMANOana GEMAN
Oana GEMAN
SSSara SharghiLavan
Sara SharghiLavan
HAHadi Abbasi
Hadi Abbasi
RTRoxana Toderean
Roxana Toderean
Octavian Adrian PostolacheOctavian Adrian Postolache
Octavian Adrian Postolache
MKMatti Karppa
Matti Karppa
The main challenges in the life of a child with autism are difficulties in communication, behavior, and social interaction. Early diagnosis of this neurodevelopmental disorder improves patient outcomes by enabling more effective, personalized interventions. This diagnosis can sometimes be difficult, especially in very young children. Non-invasive, relatively accessible, and able to reflect neural function in real time, electroencephalography (EEG) shows promise in the detection of Autism spectrum disorders (ASD). However, because EEG data is still difficult for experts to understand, machine learning and artificial intelligence (AI) are beginning to be used in this field as well. In this paper, a ResNet+BiLSTM hybrid deep network was applied and achieved high accuracy in distinguishing individuals with autism from neurotypical subjects. Since AI models typically provide predictions without clear explanations, this study employs explainable AI (XAI) methods such as SHAP (SHapley Additive exPlanations) and LIME (Local Interpretable Model-agnostic Explanations) to clarify their decision-making.Delta, theta, alpha, beta, and gamma waves, as well as ERP components P100, N100, P200, MMN, and P600, were analyzed in the two neurotypical and autistic groups that were compared in this study using EEG recordings. By integrating SHAP and LIME, the system achieved both accurate classification and transparent explanations, pointing to EEG- and ERP-based features as reliable biomarkers for ASD.