Isabela M. Benseñor

Dr. Isabela M. Benseñor

orcid

Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 May 2022 in Nature Reviews Disease Primers
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LCLayal Chaker
Layal Chaker
SRSalman Razvi
Salman Razvi
IBIsabela M. Benseñor
Isabela M. Benseñor
FAFereidoun Azizi
Fereidoun Azizi
EPElizabeth N. Pearce
Elizabeth N. Pearce
RPRobin P. Peeters
Robin P. Peeters

17 May 2021 in Nutrients
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Leandro Teixeira CacauLeandro Teixeira Cacau
Leandro Teixeira Cacau
ECEduardo De Carli
Eduardo De Carli
ACAline Carvalho
Aline Carvalho
PLPaulo Andrade Lotufo
Paulo Andrade Lotufo
Luis A. MorenoLuis A. Moreno
Luis A. Moreno
DMDirce Marchioni
Dirce Marchioni
The EAT-Lancet Commission has proposed a planetary health diet. We propose the development of the Planetary Health Diet Index (PHDI) based on this proposed reference diet. We used baseline dietary data obtained through a 114-item FFQ from 14,779 participants of the Longitudinal Study on Adult Health, a multicenter cohort study conducted in Brazil. The PHDI has 16 components and a score from 0 to 150 points. Validation and reliability analyses were performed, including principal component analyses, association with selected nutrients, differences in means between groups (for example, smokers vs. non-smokers), correlations between components and total energy intake, Cronbach’s alpha, item-item correlations, and linear regression analysis between PHDI with carbon footprint and overall dietary quality. The mean PHDI was 60.4 (95% CI 60.2:60.5). The PHDI had six dimensions, was associated in an expected direction with the selected nutrients and was significantly (p < 0.001) lower in smokers (59.0) than in non-smokers (60.6). Cronbach’s alpha value was 0.51. All correlations between components were low, as well as between components and PHDI with total energy intake. After adjustment for age and sex, the PHDI score remained associated (p < 0.001) with a higher overall dietary quality and lower carbon footprint. Thus, we confirmed the PHDI validity and reliability.

20 October 2021 in Nutrients
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Leandro Teixeira CacauLeandro Teixeira Cacau
Leandro Teixeira Cacau
IBIsabela M. Benseñor
Isabela M. Benseñor
AGAlessandra Carvalho Goulart
Alessandra Carvalho Goulart
DMDirce Marchioni
Dirce Marchioni
PLPaulo Andrade Lotufo
Paulo Andrade Lotufo
DMDirce Maria Marchioni
Dirce Maria Marchioni
The EAT-Lancet Commission has proposed a model diet to improve the health of human beings and that of the planet. Recently, we proposed the Planetary Health Diet Index (PHDI) to assess adherence of the population to this model diet. In this study, we aimed to evaluate adherence to the PHDI and obesity outcomes using baseline data from 14,515 participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The dietary data were assessed using a 114-item FFQ. Body mass index (BMI) and waist circumference (WC) were both used continuously and categorized. Linear and multinomial regression models adjusted for potential confounding factors were performed to assess the relationship between adherence to PHDI and outcomes. An inverse association was observed between adherence to PHDI and obesity indicators. Individuals with high adherence to the PHDI had lower BMI (β−0.50 95% CI−0.73:−0.27) and WC (β−1.70 95% CI−2.28:−1.12) values. They were also 24% less likely to be overweight (OR 0.76 95% CI 0.67:0.85) or obese (OR 0.76 95% CI 0.65:0.88), and they were 14% and 27% less likely to have increased WC (OR 0.86 95% CI 0.75:0.98) or substantially increased WC (OR 0.73 95% CI 0.64:0.83) than those with lower adherence. Our results showed that higher adherence to the PHDI may decrease obesity indicators.

22 November 2017 in Population Health Metrics
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EFElisabeth B. França
Elisabeth B. França
VPValéria Maria de Azeredo Passos
Valéria Maria de Azeredo Passos
DMDeborah Malta
Deborah Malta
BDBruce Duncan
Bruce Duncan
ARAntonio Luiz Ribeiro
Antonio Luiz Ribeiro
MNMohsen Naghavi
Mohsen Naghavi
Reliable data on cause of death (COD) are fundamental for planning and resource allocation priorities. We used GBD 2015 estimates to examine levels and trends for the leading causes of death in Brazil from 1990 to 2015. We describe the main analytical approaches focused on both overall and specific causes of death for Brazil and Brazilian states. There was an overall improvement in life expectancy at birth from 1990 to 2015, but with important heterogeneity among states. Reduced mortality due to diarrhea, lower respiratory infections, and other infectious diseases contributed the most for increasing life expectancy in most states from the North and Northeast regions. Reduced mortality due to cardiovascular diseases was the highest contributor in the South, Southeast, and Center West regions. However, among men, intentional injuries reduced life expectancy in 17 out of 27 states. Although age-standardized rates due to ischemic heart disease (IHD) and cerebrovascular disease declined over time, these remained the leading CODs in the country and states. In contrast, leading causes of premature mortality changed substantially - e.g., diarrheal diseases moved from 1st to 13th and then the 36th position in 1990, 2005, and 2015, respectively, while violence moved from 7th to 1st and to 2nd. Overall, the total age-standardized years of life lost (YLL) rate was reduced from 1990 to 2015, bringing the burden of premature deaths closer to expected rates given the country’s Socio-demographic Index (SDI). In 1990, IHD, stroke, diarrhea, neonatal preterm birth complications, road injury, and violence had ratios higher than the expected, while in 2015 only violence was higher, overall and in all states, according to the SDI. A widespread reduction of mortality levels occurred in Brazil from 1990 to 2015, particularly among children under 5 years old. Major shifts in mortality rates took place among communicable, maternal, neonatal, and nutritional disorders. The mortality profile has shifted to older ages with increases in non-communicable diseases as well as premature deaths due to violence. Policymakers should address health interventions accordingly.

1 September 2015 in Arquivos de Neuro-Psiquiatria
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IBIsabela M. Benseñor
Isabela M. Benseñor
AGAlessandra C. Goulart
Alessandra C. Goulart
CSCélia Landmann Szwarcwald
Célia Landmann Szwarcwald
MVMaria Lucia França Pontes Vieira
Maria Lucia França Pontes Vieira
DMDeborah Malta
Deborah Malta
PLPaulo A. Lotufo
Paulo A. Lotufo
There is scarce data about prevalence of stroke in Brazil. The National Health Survey (PNS) is a community-based epidemiological survey, with a nationally representative sample to assess the absolute numbers with respective prevalence rates of stroke and post-stroke disabilities. It was estimated 2,231.000 stroke and 568,000 stroke cases with severe disabilities. The point prevalences was 1.6% and 1.4% in men and women, respectively. The prevalences of post-stroke disabilities were 29.5% for men and 21.5% for women. Stroke prevalence rates increased with aging, low education level, among people living in urban areas with no difference according to self-reported skin color. The degree of post-stroke disability was not statistically different according to sex, race, education level or living area. This new data from PNS show high stroke prevalence rates especially in older individuals without formal education and urban dweller, but the degree of stroke disability was not determined by the sociodemographic characteristics of the Brazilian population.

TMTiana Moreira
Tiana Moreira
JPJefferson L. Polizel
Jefferson L. Polizel
ISItamar Santos
Itamar Santos
DFDemóstenes Silva Filho
Demóstenes Silva Filho
IBIsabela M. Benseñor
Isabela M. Benseñor
TMTHAIS MAUAD
THAIS MAUAD
Proximity to green spaces has been shown to be beneficial to several cardiovascular outcomes in urban spaces. Few studies, however, have analyzed the relationship between these outcomes and green space or land cover uses in low–medium income megacities, where the consequences of rapid and inordinate urbanization impose several health hazards. This study used a subgroup of the dataset from The Brazilian Longitudinal Study of Adult Health ELSA-BRASIL (n = 3418) to identify the correlation between the medical diagnosis of hypertension and green spaces in the megacity of São Paulo. Land cover classification was performed based on the random forest algorithm using geometrically corrected aerial photography (orthophoto). Three different indicators of exposure to green spaces were used: number of street trees, land cover and number of parks within 1 km. We used logistic regression models to obtain the association of the metrics exposure and health outcomes. The number of street trees in the regional governments (OR = 0.937 and number of parks within 1 km (OR = 0.876) were inversely associated with a diagnosis of hypertension. Sixty-three percent of the population had no parks within 1 km of their residence. Our data indicate the need to encourage large-scale street tree planting and increase the number of qualified parks in megacities.