Carbon capture and utilization (CCU) may offer a response to climate change mitigation from major industrial emitters. CCU can turn waste CO₂ emissions into valuable products such as chemicals and fuels. Consequently, attention has been paid to petrochemical industries as one of the best options for CCU. The largest industrial CO₂ removal monoethanol amine-based plant in Iran has been simulated with the aid of a chemical process simulator, i.e., Aspen HYSYS^® v.10. The thermodynamic properties are calculated with the acid gas property package models, which are available in Aspen HYSYS^®. The results of simulation are validated by the actual data provided by Kermanshah Petrochemical Industries Co. Results show that there is a good agreement between simulated results and real performance of the plant under different operational conditions. The main parameters such as capture efficiency in percent, the heat consumption in MJ/kg CO₂ removed, and the working capacity of the plant are calculated as a function of inlet pressure and temperature of absorber column. The best case occurred at the approximate temperature of 40 to 42 °C and atmospheric pressure with CO₂ removal of 80.8 to 81.2%; working capacity of 0.232 to 0.233; and heat consumption of 4.78 MJ/kg CO₂.