Non-invasive glucose monitoring has become a critical area of research for diabetes management, offering a less intrusive and more patient-friendly alternative to traditional methods such as finger-prick tests. This study presents a novel approach using a semi-solid tissue-mimicking phantom designed to replicate the dielectric properties of human skin and blood vessels. The phantom was simplified to focus solely on the skin layer, with embedded channels representing veins to achieve realistic glucose monitoring conditions. These channels were filled with D-(+)-Glucose solutions at varying concentrations (60 mg/dL to 200 mg/dL) to simulate physiological changes in blood glucose levels. A miniature patch antenna optimized to operate at 14 GHz with a penetration depth of approximately 1.5 mm was designed and fabricated. The antenna was tested in direct contact with the skin phantom, allowing for precise measurements of the changes in glucose concentration without interference from deeper tissue layers. Simulations and experiments demonstrated the antenna’s sensitivity to variations in glucose concentration, as evidenced by measurable shifts in the dielectric properties of the phantom. Importantly, the system enabled stationary measurements by injecting glucose solutions into the same blood vessels, eliminating the need to reposition the sensor while ensuring reliable and repeatable results. This work highlights the importance of shallow penetration depth in targeting close vessels for noninvasive glucose monitoring, and emphasizes the potential of microwave-based sensing systems as a practical solution for continuous glucose management.
In industrial smelters, sulfuric acid is manufactured using the elemental sulfur in a series of three-unit operations: elemental sulfur oxidation, sulfur dioxide catalytic conversion, and sulfur trioxide absorption. The sulfur oxidation, which is the basic step in this process, is generally performed under a sulfur combustion furnace that ensures the production of the process gas stream, which will be the main supply stream to the other unit operations. In this paper, a dynamic model is developed based on the fundamental mass and energy balance, including the sulfur oxidation and the dynamic flow behavior aspects within the furnace. The obtained model is simulated in the Matlab/Simulink environment and data from an industrial plant were used to validate the model. The simulation results and the plant measurement comparison showed an accuracy of 96%, with a mean absolute error of 16.12 °C and a root mean square error of 23.27 °C. Afterwards, the effect of different operating conditions and disturbance parameters on the sulfur combustion furnace performance were studied. Finally, the relationship and a correlation between the temperature and sulfur dioxide molar fraction at the outlet of the furnace were investigated for industrial use.