Although the immediate impact of the COVID-19 pandemic has been alleviated, its long-term effects continue to shape global health and public safety. Policymakers should prepare for potential future health crises and direct urban planning toward more sustainable outcomes. While numerous studies have examined factors influencing the risk of COVID-19, few have investigated the spatial spillover effects of urban form and green space. In this study, we quantified urban form using landscape pattern indices, represented population mobility with the Baidu Migration Scale Index, and assessed the role of key influencing factors on the epidemic through STIRPAT and spatial Durbin models. Our findings reveal that population migration from Wuhan had a significant local impact on the spread of COVID-19. These factors not only intensified local transmission, but also triggered positive spatial spillover effects, spreading the virus to neighboring regions. We also found that green space connectivity (pc₅) plays a crucial role in reducing the spread of the virus, both locally and in surrounding areas. High green space connectivity helps mitigate disease transmission during an epidemic. In contrast, the spatial configuration and unipolarity of urban areas (pc₁) contributed to the increased spread of the virus to neighboring cities. Ultimately, balancing building density with green space distribution is essential for enhancing urban resilience. This research provides new insights into sustainable urban planning and helps us understand the impact of the spillover effects of gray–green space forms on public health and safety.

Urban thermal environments critically impact human settlements and sustainable urban development. In this study, a multi-index framework integrating Landsat TM/ETM+/OLI observations (2004–2019) is developed to quantify the contributions of “source–sink” landscapes to urban heat island (UHI) dynamics in Guangzhou, China, with direct implications for advancing sustainable development. Urban–rural gradient analysis was combined with emerging spatiotemporal hotspot modeling, revealing the following results: (1) there were thermal spatial heterogeneity with pronounced heat accumulation in core urban zones and improved thermal profiles in northern sectors, reflecting a transition from “more sources, fewer sinks” in the southwest to “fewer sources, more sinks” in the northeast; (2) UHIs were effectively mitigated within 25–35 km of the city center, with the landscape effect index (LI > 1) indicating successful sink-dominated cooling; (3) spatiotemporal hotspots were observed, including persistent UHIs in old urban areas contrasting with environmentally vulnerable coldspots in suburban mountainous regions, highlighting uneven thermal risks. This framework provides actionable strategies for sustainable urban planning, including optimizing green–blue infrastructure in UHI cores, enforcing cool material standards, and zoning expansion based on source–sink dynamics. This study bridges landscape ecology and sustainable development, offering a replicable model for cities worldwide to mitigate UHI effects through evidence-based landscape management.