Song DJ, et al. Allergy Asthma Immunol Res. 2018 Nov;10(6):591-613. https://doi.org/10.4168/aair.2018.10.6.591

Jeon YH, et al. J Korean Med Sci. 2019 Mar;34(13):e106. https://doi.org/10.3346/jkms.2019.34.e106

Pollen-food allergy syndrome (PFAS) is an immunoglobulin E-mediated immediate allergic reaction caused by cross-reactivity between pollen and the antigens of foods—such as fruits, vegetables, or nuts—in patients with pollen allergy. A 42.7% prevalence of PFAS in Korean pediatric patients with pollinosis was recently reported. PFAS is often called oral allergy syndrome because of mild symptoms such as itching, urticaria, and edema mainly in the lips, mouth, and pharynx that appear after food ingestion. However, reports of systemic reactions such as anaphylaxis have been increasing recently. This diversity in the degree of symptoms is related to the types of trigger foods and the characteristics of allergens, such as heat stability. When pediatric patients with pollen allergy are treated, attention should be paid to PFAS and an active effort should be made to diagnose it.

Choi JH, et al. Allergy Asthma Immunol Res. 2020 Sep;12(5):750-770. https://doi.org/10.4168/aair.2020.12.5.750

Song WJ, et al. Allergy Asthma Immunol Res. 2020 Jul;12(4):563-578. https://doi.org/10.4168/aair.2020.12.4.563

Jeon YH, et al. J Korean Med Sci. 2022 Jan;37(4):e30. https://doi.org/10.3346/jkms.2022.37.e30