With the increasing demand for alternatives to traditional indium tin oxide (ITO), copper nanowires (Cu NWs) have gained significant attention due to their excellent conductivity, cost-effectiveness, and ease of synthesis. However, challenges such as wire–wire contact resistance and oxidation susceptibility hinder their practical applications. This review discusses the development and challenges associated with Cu NW-based flexible transparent conductors (FTCs). Cu NWs are considered a promising alternative to traditional materials like ITO, thanks to their high electrical conductivity and low cost. This paper explores various synthesis methods for Cu NWs, including template-assisted synthesis, hydrazine reduction, and hydrothermal processes, while highlighting the advantages and limitations of each approach. The key challenges, such as contact resistance, oxidation, and the need for protective coatings, are also addressed. Several strategies to enhance the conductivity and stability of Cu NW-based FTCs are proposed, including thermal sintering, laser sintering, acid treatment, and photonic sintering. Additionally, protective coatings like noble metal core–shell layers, electroplated layers, and conductive polymers like PEDOT:PSS are discussed as effective solutions. The integration of graphene with Cu NWs is explored as a promising method to improve oxidation resistance and overall performance. The review concludes with an outlook on the future of Cu NWs in flexible electronics, emphasizing the need for scalable, cost-effective solutions to overcome current challenges and improve the practical application of Cu NW-based FTCs in advanced technologies such as displays, solar cells, and flexible electronics.