Syndrome differentiation and disease diagnosis are central to Traditional Asian Medicine (TAM) because they guide personalized treatment. Yet, most TAM courses give students few structured opportunities to practise these paired skills. We developed Gen-SynDi, a knowledge-guided generative-AI framework that links syndrome differentiation with disease diagnosis to improve training. Using standardized patient files from the National Institute for Korean Medicine Development, we built a fatigue-focused dataset covering five Western-defined diseases and seven TAM syndromes. Carefully designed prompts and a large language model produced 28 virtual patient cases by joining compatible disease–syndrome pairs while preserving clinical realism. Inside an interactive web simulation, students conduct history-taking, receive free-text answers, and propose both syndrome and disease diagnoses; immediate feedback highlights missing questions, reasoning gaps, and overall accuracy. A built-in scoring module supplies quantitative measures of inquiry coverage and diagnostic precision, plus brief explanations of overlooked clues. A prompt-component role analysis confirmed that our prompt design improves response fidelity, and external experts endorsed the scenarios’ realism and educational value. Gen-SynDi therefore offers a scalable bridge between textbook knowledge and clinical practice, strengthening learners’ skills in differential diagnosis and syndrome differentiation.

Purpose: First-year students can form a preconception based on life experiences before entering college and identifying learners’ existing characteristics can be useful foundation data for curriculum development. This study examines what preconceptions freshman students had about medicine before entering medical school.Methods: A total of 110 first-year students were asked about what preconceptions they had about “medicine”. A total of 1,124 data were used in the content analysis method.Results: The results were extracted into 5, and 12 twelve categories. On the theme of “scientific discipline”, the knowledge students had about general health was based on scant expertise and little evidence. Students perceived medicine as Western and scientific, considering Korean traditional medicine as unscientific. Students believed that “medical practice” should be a “disease treatment” and “patient-centered” approach rather than a “social responsibility”. In “the role of the doctor”, students were concerned about the doctor's being financially stable on the positive side, and about the high-intensity workload on the negative side. In “medical education”, students believed that studying medicine would be “hard and difficult” because of the “importance of memorizing” and “extensive study load”. In “specialty stereotype”, students had biases that were mostly concentrated on “psychiatry” and “surgery”Conclusion: Perception of “medicine” has been revealed to a varied range of themes, but some have been inaccurate or unrealistic. These prejudices and groundless beliefs have a gap with the learning outcomes that students should achieve in the curriculum, and these preconceptions seem to have been influenced by South Korea’s unique cultural context.

The purpose of this study was to systematically review published articles on Yaksun studies and provide understanding on current and future studies with Yaksun and medical treatment with food. We performed systematic review on the Yaksun studies published recent 16 years from 2000 to 2016 using seven Korean database on research articles. We found 90 articles are relevant for the analysis. The articles on Yaksun were significantly increased since 2005. As for the research field, Food Science (39 articles, 31.0%) and Tourism (20 articles, 15.9%) were dominant throughout the years. Researchers from Science of cookery (35 articles, 35.0%) and Food and Nutrition (32 articles, 32.0%) were found to be most frequent. The prime type of research on Yaksun were the We found that the Survey (49 articles, 52.7%) was the most frequent research method and basic research for providing related data (41 articles, 45.6%) was easily found as for the purpose of the article. We found that there were insufficient reports on clinical efficacy of Yaksun, especially with the treatment of diseases. The interest of medical professionals is needed for the better understanding on the medical use of Yaksun and therapeutic diet which has potentials for integrative medicine.

Oxidative stress, a driver of liver pathology, remains a challenge in clinical management, necessitating innovative approaches. In this research, we delved into the therapeutic potential of polyphenols for oxidative liver injury using a multiscale network analysis framework. From the Phenol-Explorer database, we curated a list of polyphenols along with their corresponding PubChem IDs. Verified target information was then collated from multiple databases. We subsequently measured the propagative effects of these compounds and prioritized a ranking based on their correlation scores for oxidative liver injury. This result underwent evaluation to discern its effectiveness in differentiating between known and unknown polyphenols, demonstrating superior performance over chance level in distinguishing these compounds. We found that lariciresinol and isopimpinellin yielded high correlation scores in relation to oxidative liver injury without reported evidence. By analyzing the impact on a multiscale network, we found that lariciresinol and isopimpinellin were predicted to offer beneficial effects on the disease by directly acting on targets such as CASP3, NR1I2, and CYP3A4 or by modulating biological functions related to the apoptotic process and oxidative stress. This study not only corroborates the efficacy of identified polyphenols in liver health but also opens avenues for future investigations into their mechanistic actions.

Media characters’ physical and psychological traits are crucial for character development and audience engagement. This study examines East Asian perspectives on the audience’s perceptions of the physical appearance and personality, using Eum-Yang biopsychological Sasang theory, of five characters from the Netflix series “Squid Game”. A total of 221 university students assessed the traits of five “Squid Game” characters using the Sasang Personality Questionnaire (SPQ) and a visual Body Mass Index (BMI). ANOVA and Profile Analysis revealed significant and comprehensive differences in the SPQ and its subscales (behavior, SPQ-B; cognition, SPQ-C; and emotion, SPQ-E) as well as BMI among the five drama characters. More specifically, Seong Gi-hun (SGH) and Han Mi-nyeo (HMN) were So-Yang types (high SPQ, moderate BMI), Cho Sang-woo (CSW) and Kang Sae-byeok (KSB) were So-Eum types (low SPQ, low BMI), and Jang Deok-su (JDS) was Tae-Eum type (moderate SPQ, high BMI). Psychological profiling showed two patterns: V-shaped (high SPQ-B, low SPQ-C, high SPQ-E) for SGH, HMN, and JDS, and A-shaped (low SPQ-B, high SPQ-C, low SPQ-E) for CSW and KSB. These results contribute to media psychology by highlighting the relevance of Eum-Yang and Sasang typology for creating and analyzing complex characters, thereby enhancing global understanding for East Asian biopsychosocial theories.

Objectives: Team-based learning (TBL) expands in healthcare education to enhance students’ competency in self-directed learning, effective communication, collaboration, clinical reasoning, and problem-solving in clinical settings. This study investigated students’ perspectives in Korean Medicine (KM) regarding their clinical experience with a real patient in a pilot TBL module using a mixed-methods approach.Methods: A 3-hour TBL session was conducted with 36 final-year KM students divided into eight groups of 4–5 students each. The students conducted a medical interview and performed physical examinations and clinical reasoning for the patient with neck pain. Students were then surveyed regarding their satisfaction with TBL, relevance of the program’s objectives and content, and suggestions for program improvement. Four students from different teams were interviewed to explore their experiences in the TBL class, and a qualitative thematic analysis was conducted.Results: Eleven students (31%) completed questionnaires. All students found TBL to be beneficial and satisfactory and considered it highly pertinent to their future duties. Interacting with a real patient facilitated learning, as students identified their weaknesses. Through team-based care, students actively engaged in discussions about clinical reasoning and treatment plans, thereby expanding their perspectives on patient care through their peers. The group activities reflected the characteristics of traditional medical practice, in which diagnosis and treatment might be timely completed in primary care, with multiple therapeutic approaches available for the same diagnosis. The students proposed promoting pre-learning, modifying group composition methods, extending class time, and modifying feedback methods using post-it notes to improve the TBL module.Conclusion: Group practice with a real patient facilitates self-directed learning and expands students’ understanding of clinical reasoning and perspectives on patient care through live discussions. The pilot TBL module should be included in KM curricula to ensure students’ sufficient experience in decision-making and communication before practicing individually as licensed healthcare providers.