Chittaranjan Kole

Prof. Chittaranjan Kole

orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 February 2022 in Frontiers in Plant Science
Verified
Journal Article
Open access
TBTusar Kanti Behera
Tusar Kanti Behera
RKRam Krishna
Ram Krishna
WAWaquar Akhter Ansari
Waquar Akhter Ansari
MAMohd Aamir
Mohd Aamir
Pradeep KumarPradeep Kumar
Pradeep Kumar
CKChittaranjan Kole
Chittaranjan Kole
Salt stress is one of the most important abiotic stresses as it persists throughout the plant life cycle. The productivity of crops is prominently affected by soil salinization due to faulty agricultural practices, increasing human activities, and natural processes. Approximately 10% of the total land area (950 Mha) and 50% of the total irrigated area (230 Mha) in the world are under salt stress. As a consequence, an annual loss of 12 billion US$ is estimated because of reduction in agriculture production inflicted by salt stress. The severity of salt stress will increase in the upcoming years with the increasing world population, and hence the forced use of poor-quality soil and irrigation water. Unfortunately, majority of the vegetable crops, such as bean, carrot, celery, eggplant, lettuce, muskmelon, okra, pea, pepper, potato, spinach, and tomato, have very low salinity threshold (ECt, which ranged from 1 to 2.5 dS m–1 in saturated soil). These crops used almost every part of the world and lakes’ novel salt tolerance gene within their gene pool. Salt stress severely affects the yield and quality of these crops. To resolve this issue, novel genes governing salt tolerance under extreme salt stress were identified and transferred to the vegetable crops. The vegetable improvement for salt tolerance will require not only the yield influencing trait but also target those characters or traits that directly influence the salt stress to the crop developmental stage. Genetic engineering and grafting is the potential tool which can improve salt tolerance in vegetable crop regardless of species barriers. In the present review, an updated detail of the various physio-biochemical and molecular aspects involved in salt stress have been explored.

8 November 2021 in Frontiers in Genetics
Verified
Journal Article
Open access
SNSpurthi N. Nayak
Spurthi N. Nayak
BAB. Aravind
B. Aravind
SMSachin S. Malavalli
Sachin S. Malavalli
BSB. S. Sukanth
B. S. Sukanth
RPR. Poornima
R. Poornima
NPNaveen Puppala
Naveen Puppala
Functional foods are natural products of plants that have health benefits beyond necessary nutrition. Functional foods are abundant in fruits, vegetables, spices, beverages and some are found in cereals, millets, pulses and oilseeds. Efforts to identify functional foods in our diet and their beneficial aspects are limited to few crops. Advances in sequencing and availability of different omics technologies have given opportunity to utilize these tools to enhance the functional components of the foods, thus ensuring the nutritional security. Integrated omics approaches including genomics, transcriptomics, proteomics, metabolomics coupled with artificial intelligence and machine learning approaches can be used to improve the crops. This review provides insights into omics studies that are carried out to find the active components and crop improvement by enhancing the functional compounds in different plants including cereals, millets, pulses, oilseeds, fruits, vegetables, spices, beverages and medicinal plants. There is a need to characterize functional foods that are being used in traditional medicines, as well as utilization of this knowledge to improve the staple foods in order to tackle malnutrition and hunger more effectively.

20 April 2023 in Microorganisms
Verified
Journal Article
Open access
PDF file
SOSandhya Ojha
Sandhya Ojha
NPNIL SANJAY PATIL
NIL SANJAY PATIL
MJMukul Jain
Mukul Jain
CKChittaranjan Kole
Chittaranjan Kole
Prashant KaushikPrashant Kaushik
Prashant Kaushik
Neurodegenerative disorders (ND) are a group of conditions that affect the neurons in the brain and spinal cord, leading to their degeneration and eventually causing the loss of function in the affected areas. These disorders can be caused by a range of factors, including genetics, environmental factors, and lifestyle choices. Major pathological signs of these diseases are protein misfolding, proteosomal dysfunction, aggregation, inadequate degradation, oxidative stress, free radical formation, mitochondrial dysfunctions, impaired bioenergetics, DNA damage, fragmentation of Golgi apparatus neurons, disruption of axonal transport, dysfunction of neurotrophins (NTFs), neuroinflammatory or neuroimmune processes, and neurohumoral symptoms. According to recent studies, defects or imbalances in gut microbiota can directly lead to neurological disorders through the gut-brain axis. Probiotics in ND are recommended to prevent cognitive dysfunction, which is a major symptom of these diseases. Many in vivo and clinical trials have revealed that probiotics (Lactobacillus acidophilus, Bifidobacterium bifidum, and Lactobacillus casei, etc.) are effective candidates against the progression of ND. It has been proven that the inflammatory process and oxidative stress can be modulated by modifying the gut microbiota with the help of probiotics. As a result, this study provides an overview of the available data, bacterial variety, gut-brain axis defects, and probiotics’ mode of action in averting ND. A literature search on particular sites, including PubMed, Nature, and Springer Link, has identified articles that might be pertinent to this subject. The search contains the following few groups of terms: (1) Neurodegenerative disorders and Probiotics OR (2) Probiotics and Neurodegenerative disorders. The outcomes of this study aid in elucidating the relationship between the effects of probiotics on different neurodegenerative disorders. This systematic review will assist in discovering new treatments in the future, as probiotics are generally safe and cause mild side effects in some cases in the human body.

1 January 2021 in Breeding Science
Verified
Journal Article
Open access
PDF file
KSKenta Shirasawa
Kenta Shirasawa
DHDaijiro Harada
Daijiro Harada
HHHideki Hirakawa
Hideki Hirakawa
SISachiko Isobe
Sachiko Isobe
CKChittaranjan Kole
Chittaranjan Kole
Genome sequence analysis in higher plants began with the whole-genome sequencing of Arabidopsis thaliana. Owing to the great advances in sequencing technologies, also known as next-generation sequencing (NGS) technologies, genomes of more than 300 plant species have been sequenced to date. Long-read sequencing technologies, together with sequence scaffolding methods, have enabled the synthesis of chromosome-level de novo genome sequence assemblies, which has further allowed comparative analysis of the structural features of multiple plant genomes, thus elucidating the evolutionary history of plants. However, the quality of the assembled chromosome-level sequences varies among plant species. In this review, we summarize the status of chromosome-level assemblies of 114 plant species, with genome sizes ranging from 125 Mb to 16.9 Gb. While the average genome coverage of the assembled sequences reached up to 88.7%, the average coverage of chromosome-level pseudomolecules was 72.9%. Thus, further improvements in sequencing technologies and scaffolding, and data analysis methods, are required to establish gap-free telomere-to-telomere genome sequence assemblies. With the forthcoming new technologies, we are going to enter into a new genomics era where pan-genomics and the >1,000 or >1 million genomes’ project will be routine in higher plants.

10 December 2025 in The Plant Genome
Verified
Journal Article
Open access
CKChittaranjan Kole
Chittaranjan Kole
SPSarita Pandey
Sarita Pandey
JYJeshima K Yasin
Jeshima K Yasin
sujan Mamidisujan Mamidi
sujan Mamidi
ABAbhishek Bohra
Abhishek Bohra
MBManikanda Boopathi
Manikanda Boopathi
The global population, set to exceed 10 billion by 2050, presents enormous challenges to food, health, nutrition, energy, and environmental security. Plant breeding methods have continuously evolved to develop improved crop varieties to meet these demands. Among the recent developments, genetically modified crops (GMCs) have emerged as a viable option to enhance crop yields, nutritional value, biofuel potential, and climatic adaptability. However, extensive application of GMCs is a very controversial subject due to biosafety issues, environmental impacts, economic viability, and legal considerations. This review presents a critical evaluation of the merits and limitations of GMCs, along with a discussion of available alternative approaches, with particular reference to the Indian context. While GMCs have been developed with increased yields, improved shelf life, reduced pesticide and herbicide use, and improved stress tolerance, potential risks such as health hazards and socioeconomic impacts on smallholding farmers in the developing world cannot be disregarded. Besides, regulatory policies and public perception have a significant influence on the acceptability and commercialization of GMCs, especially in countries like India. The discussion therefore encompasses other sustainable alternatives, including marker‐assisted selection, genomics‐aided breeding, cisgenesis, intragenesis, and stringently regulated gene editing, that embody environment‐friendly approaches to agricultural enhancement. A collective assessment of these techniques is presented in order to examine their prospects for delivering long‐term biosecurity without compromising environmental and human health. By integrating scientific advances, policy environments, and social perceptions, this review aims to present a balanced perspective of GMCs and their role in the future of global agriculture, particularly in the Global South.

30 January 2020
Verified
Book Chapter
Closed access
PDF file
TBTusar Kanti Behera
Tusar Kanti Behera
HMHideo Matsumura
Hideo Matsumura
CKChittaranjan Kole
Chittaranjan Kole