Martina Rosto

Dr. Martina Rosto


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 April 2025 in Veterinary Sciences
Verified
Journal Article
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ARAndrea Rubini
Andrea Rubini
Roberto Di ViaRoberto Di Via
Roberto Di Via
VPVito Paolo Pastore
Vito Paolo Pastore
FSFRANCESCA DEL SIGNORE
FRANCESCA DEL SIGNORE
MRMartina Rosto
Martina Rosto
Massimo VignoliMassimo Vignoli
Massimo Vignoli
The integration of artificial intelligence (AI) into chest radiography (CXR) has greatly impacted both human and veterinary medicine, enhancing diagnostic speed, accuracy, and efficiency. In human medicine, AI has been extensively studied, improving the identification of thoracic abnormalities, diagnostic precision in emergencies, and the classification of complex conditions such as tuberculosis, pneumonia, and COVID-19. Deep learning-based models assist radiologists by detecting patterns, generating probability maps, and predicting outcomes like heart failure. However, AI is still supplementary to clinical expertise due to challenges such as data limitations, algorithmic biases, and the need for extensive validation. Ethical concerns and regulatory constraints also hinder full implementation. In veterinary medicine, AI is still in its early stages and is rarely used; however, it has the potential to become a valuable tool for supporting radiologists in the future. However, challenges include smaller datasets, breed variability, and limited research. Addressing these through focused research on species with less phenotypic variability (like cats) and cross-sector collaborations could advance AI in veterinary medicine. Both fields demonstrate AI’s potential to enhance diagnostics but emphasize the ongoing need for human expertise in clinical decision making. Differences in anatomy structure between the two fields must be considered for effective AI adaptation.

16 May 2025 in Animals
Verified
Journal Article
Open access
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SSStefano Spada
Stefano Spada
DFDaniela De Felice
Daniela De Felice
ACAlfonso Calabria
Alfonso Calabria
FCFrancesca Carletti
Francesca Carletti
LALuiz Aires
Luiz Aires
Marco RussoMarco Russo
Marco Russo
Cryptorchidism consists in the failure of one or both testicles to fully descend into the scrotum. The position of the retained testes can be abdominal or inguinal and may occur unilaterally or bilaterally. This retrospective, multi-center study aimed to describe the computed tomography (CT) features of retained testes in dogs. Nineteen CT scans of dogs, with either unilateral or bilateral cryptorchidism, were analyzed with both pre- and post-contrast imaging. The location, size, shape, margins, homogeneous parenchyma, and density calculated were examined with the Hounsfield unit. Statistical analyses were performed to assess the differences between the scrotal (ST) and undescended testes (UT) and to detect any correlation between the features, ages, and size of the dog. CT identified the retained testes and provided enhanced three-dimensional visualization compared to traditional ultrasound. This study revealed that the UT were significantly smaller than ST, with UT measuring around 70% of ST size. Additionally, the UT exhibited increased density in both pre- and post-contrast scans, potentially due to the reduced or absent spermatogenesis or to histological changes occurring in the parenchyma. While CT showed clear advantages, such as three-dimensional spatial resolution and deeper tissue penetration, limitations such as general anesthesia and radiation exposure should also be considered. However, the present study showed that CT could serve as a valuable second step tool in cases where ultrasound fails, particularly in challenging anatomical situations.

12 October 2024 in Animals
Verified
Journal Article
Open access
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FSFRANCESCA DEL SIGNORE
FRANCESCA DEL SIGNORE
SDStefania De Dominicis
Stefania De Dominicis
Camilla SmoglicaCamilla Smoglica
Camilla Smoglica
MRMartina Rosto
Martina Rosto
ABAndrea De Bonis
Andrea De Bonis
Massimo VignoliMassimo Vignoli
Massimo Vignoli
Strain elastography (SE) evaluates tissue stiffness, providing qualitative and semiquantitative evaluation, with a strain ratio (SR) > 1 indicating that the target lesion is stiffer than the reference tissue. The patellar tendon has been described as soft in healthy dogs and hard in dogs with cranial cruciate ligament rupture, but SR usefulness has not been assessed. Dogs were divided into healthy (G1) and at least 1 month after surgery (G2) groups. Thickness was recorded, and a B-mode score of 0–3 was determined based on the abnormality’s severity. SE was qualitatively performed with a score of 1–4, and EI was recorded on the whole ligament and in proximal, intermediate and distal areas; SR was collected with the fat pad and cutis/subcutis. G1 was significantly thinner, with a lower score than G2 and a more elastic pattern. EI for G1 was significantly lower than G2 for the whole tendon and the single portions, and EI for the distal portion was significantly lower than the proximal and intermediate one in G2. SR was 1 in G2 for both the fat pad and cutis/subcutis. These data suggest that after surgery, the tendon may become non-uniformly stiffer. The cutis/subcutis appears to be a more reliable reference tissue than the infrapatellar fat pad.

31 December 2023 in Animals
Verified
Journal Article
Open access
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APAndrea Paolini
Andrea Paolini
Massimo VignoliMassimo Vignoli
Massimo Vignoli
Nicola BernabòNicola Bernabò
Nicola Bernabò
ABAmanda Bianchi
Amanda Bianchi
RTRoberto Tamburro
Roberto Tamburro
ICIlaria Cerasoli
Ilaria Cerasoli
Cats are often easily stressed and uncooperative. The use of sedative agents in the feline species is widely used to perform even minor clinical and diagnostic procedures. The aim of this study is to assess the impact on tear film production of the intrarectal route (IR) administration of a mixture of dexmedetomidine, ketamine and midazolam in comparison with the intramuscular (IM) one. A group of twenty cats were involved in a randomized and blinded clinical trial. A clinical and ophthalmological examination was conducted on the cats. The IR group received dexmedetomidine 0.003 mg kg−1, ketamine 4 mg kg−1 and midazolam 0.4 mg kg−1; the IM group received dexmedetomidine 0.003 mg kg−1, ketamine 2 mg kg−1 and midazolam 0.2 mg kg−1. A Shirmer tear test I (STT- I) was conducted 1 h before sedation and 2′, 10′, 20′, 30′, 40′, and 80′ post drug administration. The reaction to STT-I administration was also evaluated. The IM group has a lower mean tear production than the IR group for all time points evaluated. Cats in the IM group showed less reaction to STT-I administration. This study may suggest that the effect of sedative agents administered by the IR route has a lower incidence on tear production than the IM one. The use of eye lubricant is recommended in any case.

10 February 2025 in Animals
Verified
Journal Article
Open access
PDF file
FSFRANCESCA DEL SIGNORE
FRANCESCA DEL SIGNORE
RBRoberta Bucci
Roberta Bucci
Massimo VignoliMassimo Vignoli
Massimo Vignoli
Marco RussoMarco Russo
Marco Russo
Camilla SmoglicaCamilla Smoglica
Camilla Smoglica
SPSalvatore Parrillo
Salvatore Parrillo
Sonoelastography is a rapid and non-invasive ultrasound-based technique to assess tissue elasticity. Interest in this technique’s application in veterinary medicine is progressively increasing, with preliminary reports also available to assess canine testicular parenchyma abnormalities. Since elastographic techniques are different and it is of paramount importance to standardize procedures, this work aimed to compare two different elastographic techniques, SE and 2D SWE, on the same testes and compare the data with the current literature. Thirty healthy canine testes were included, and complete B-mode, color and power Doppler examinations were performed on each one. SE was performed qualitatively through an elastogram evaluation and semiquantitatively comparing the parenchyma with peripheral skin. 2D SWE was performed and m/s measurements were taken. Each measurement was collected in the cranial, middle and caudal portions, considering the sections above and below the mediastinum separately. The healthy testes appeared to be intermediate in stiffness with differences in the various portions for SE and expressed a mean value from 1.3 m/s to 1.4 m/s for 2D SWE, consistent with the previous literature. Considering the technical specifics of the software for the two elastography methods, both of them are valuable in assessing canine testis stiffness and are potentially clinically appliable.

21 October 2024 in Veterinary Sciences
Verified
Journal Article
Open access
PDF file
ABAndrea De Bonis
Andrea De Bonis
FSFrancesco Simeoni
Francesco Simeoni
APAndrea Paolini
Andrea Paolini
MRMartina Rosto
Martina Rosto
FSFRANCESCA DEL SIGNORE
FRANCESCA DEL SIGNORE
Massimo VignoliMassimo Vignoli
Massimo Vignoli
Subcutaneous lesions in dogs are common in clinical practice. This prospective clinical study aims to compare B-flow and CEUS for the characterization of subcutaneous lesions evaluating their usefulness to distinguish benign subcutaneous lesions from malignant ones. Dogs were enrolled and ultrasound cine-loops were achieved in B-mode, Colour Doppler, Power Doppler, B-flow and CEUS. Lesions vascularisation highlighted through B-flow and CEUS were classified into five patterns: P1, absence of contrast uptake; P2, enhancement only in the peripheral area of the lesion; P3, thin (<2 mm) and few vessels (2 mm) and more numerous vessels (>5/field); P5 enhancement with a reticular aspect and both thick and thin bands inside. Patterns highlighted with B-flow and CEUS were compared to a histological diagnosis of subcutaneous lesions. A total of 24 dogs and 30 subcutaneous nodules were included and divided into three groups: 3 non-neoplastic, 16 benign tumours and 11 malignant tumours. There was a statistically significant difference for B-flow and CEUS to differentiate benign tumours from malignant tumours. B-flow and CEUS had an excellent agreement. B-flow and CEUS displayed similar ability to evaluate different patterns and could be helpful in the evaluation of subcutaneous nodules.