Computed tomography scans are among the most used medical imaging modalities. With increased popularity and usage, the need for maintenance also increases. In this work, the problem is tackled using machine learning methods to create a predictive maintenance system for the classification of faulty X-ray tubes. Data for 137 different CT machines were collected, with 128 deemed to fulfil the quality criteria of the study. Of these, 66 have had X-ray tubes subsequently replaced. Afterwards, auto-regressive model coefficients and wavelet coefficients, as standard features in the area, are extracted. For classification, a set of different classical machine learning approaches is used alongside two different architectures of neural networks—1D VGG-style CNN and LSTM RNN. In total, seven different machine learning models are investigated. The best-performing model proved to be an LSTM trained on trimmed and normalised input data, with an accuracy of 87% and a recall of 100% for the faulty class. The developed model has the potential to maximise the uptime of CT machines and help mitigate the adverse effects of machine breakdowns.