Thermal comfort in public buildings is crucial for occupant well-being and energy efficiency. This study employs TRNSYS software to simulate the effects of thermal mass, window performance, and window–wall ratio (WWR) on summer thermal comfort. The results indicate that without energy-saving measures, increased thermal mass raises daily average maximum and minimum temperatures by 0.33–0.96 °C and 0.14–0.94 °C, respectively. Enhanced WWRs lead to higher daily average maximum and minimum temperatures for double-glazed windows (0.18–0.61 °C and 0.07–0.62 °C, respectively), while single-glazed windows show increased maximum temperatures (0.18–1.86 °C) but decreased minimum temperatures (−0.01 to −0.72 °C). Thermal mass has a modest effect on indoor overheating during high outdoor temperatures. Double-glazed windows and lower WWRs effectively reduce indoor overheating, decreasing the attenuation coefficient by 2.13–28.94%. Conversely, single-glazed windows and higher WWRs enhance heat dissipation, increasing daily average temperature fluctuations by 2.33–44.18%. Notably, single-glazed windows with WWRs ≥ 50% improve thermal comfort by reducing extreme superheat temperature occurrence in heavy-thermal-mass buildings by 0.81 to 14.63%. Despite lower cooling loads with heavy thermal mass, double-glazed windows, and low WWRs, the study suggests that single-glazed windows and high WWRs can enhance summer thermal comfort. Therefore, reasonable shading measures and lighter thermal mass are recommended for such buildings.