Staphylococcus aureus is one of the causes of both community and healthcare-associated bacteremia. The attributable mortality of S. aureus bacteremia (SAB) is still higher and predictors for mortality and clinical outcomes of this condition are need to be clarified. In this prospective observational study, we aimed to examine the predictive factors for mortality in patients with SAB in eight Turkish tertiary care hospitals. Adult patients with signs and symptoms of bacteremia with positive blood cultures for S. aureus were included. All data for episodes of SAB including demographics, clinical and laboratory findings, antibiotics, and outcome were recorded for a 3-year (2010–2012) period. Cox proportional hazard model with forward selection was used to assess the independent effect of risk factors on mortality. A 28-day mortality was the dependent variable in the Cox regression analysis. A total of 255 episodes of SAB were enrolled. The median age of the patients was 59 years. Fifty-five percent of the episodes were considered as primary SAB and vascular catheter was the source of 42.1 %. Healthcare associated SAB was defined in 55.7 %. Blood cultures yielded methicillin-resistant S. aureus (MRSA) as a cause of SAB in 39.2 %. Initial empirical therapy was inappropriate in 28.2 %. Although overall mortality was observed in 52 (20.4 %), 28-day mortality rate was 15.3 %. Both the numbers of initial inappropriate empirical antibiotic treatment and the median hours to start an appropriate antibiotic between the cases of fatal outcome and survivors after fever onset were found to be similar (12/39 vs 60/216 and 6 vs 12 h, respectively; p > 0.05). High Charlson comorbidity index (CCI) score (p = 0.002), MRSA (p = 0.017), intensive care unit (ICU) admission (p < 0.001) and prior exposure to antibiotics (p = 0.002) all were significantly associated with mortality. The Cox analysis defined age [Hazard Ratio (HR) 1.03; p = 0.023], ICU admission (HR 6.9; p = 0.002), and high CCI score (HR 1.32; p = 0.002) as the independent predictive factors mortality. The results of this prospective study showed that age, ICU stay and high CCI score of a patient were the independent predictors of mortality and MRSA was also significantly associated with mortality in SAB.
31 August 2021 in Journal of Clinical Medicine of Kazakhstan
Background: COVID 19, which affects all areas of life, is perhaps one of the most studied subjects in the field of medicine, and the number of global publications is increasing day by day. The nursing profession and practices have also been directly affected by this rapid stream of broadcasts. Objective: The study was planned to examine in detail the studies on 'COVID and nursing' and to guide the studies in the future. Design: In our study, the Web of Science (WOS) database was scanned to search for publications with topics of’ nursing 'or' SARS COV-2' , 'nurse' and 'COVID 19' , 'nursing' and 'COVID 19' and 'nurse' and 'SARS COV-2' were reviewed. Results: A total of 562 publications were included in the study. The country with the highest number of publications was the United States (32%). While 388 (69%) of the publications were cited, it was determined that 174 (31%) of them were not cited at all. The average number of citations of these 562 publications was found to be 3.28. The H index reached by these publications, which were cited 1.843 times in total, was found to be 17. The most cited journal of ours is It was the New England Journal of Medicine (369 citations). Conclusion: As in every field of publication, the pandemic has been effective in the field of nursing, and the number of publications has increased globally. Considering the citation rates of the publications, it was determined that there is a wide field of study in this field.
22 October 2021 in Iberoamerican Journal of Medicine
Introduction: Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is important to quickly recognize the disease by following current diagnosis and treatment methods, to identify the causative agent and to treat accordingly. Both the epidemiology and the management of IE are changing due to medical advances. This situation may also be reflected in scientific publications. We aimed to analyze the global researches on IE. Material and methods: The Scopus database was searched for bibliometric analysis without selecting document type. Data were retrieved for the time period January 1, 1940 and Semptember 26, 2021, containing the keywords " Infective’’ and’’endocarditis " in their title. Results: 7911 publications were included in the study. The first publication was made in the year 1891. Most of the publications were research articles [n=5784 (73.11%)] and were from the United States of America (USA) [n =1622 (20.50%)]. Japan, France, United Kingdom and Spain were also in the top 5 publishing countries on IE. Conclusions: Infective endocarditis is still an important reason of mortality, and there are many unanswered questions about the managament and preventation of this disease. This situation reflected the scientific publications. Since this is a global problem, not just some developed countries involved in the IE research, also more countries should be encouraged to participate the studies on IE.
30 December 2021 in Infectious Diseases and Clinical Microbiology
Coronavirus disease 2019 (COVID-19) was declined as a pandemic by the World Health Organization (WHO) in March 2020. The initial diagnosis of the disease was made in a very complex process. In addition to treating and preventing its spread, vaccination (...)
30 April 2021 in Infectious Diseases and Clinical Microbiology
Acinetobacter species are gaining resistance to antibiotics, and they have become one of the most important pathogens causing nosocomial and healthcare-associated infections, especially in intensive care units, due to their ability to lead to epidemics. A. baumannii, particularly the multidrug-resistant isolates, have been reported worldwide, especially in recent years. It causes mortality up to 40%, especially because of increased antibiotic resistance
27 November 2021 in Iberoamerican Journal of Medicine
Introduction: Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods: Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords “pressure ulcer” or “bedsore” or “decubitus ulcer” or “decubitus” or “pressure sore”. Results: 4,361 articles were analyzed in terms of study criteria. The first article was published in the year 1849 and 52.94 % of articles were published after the year 2011. Most of the articles were written in English (87.6%) language. The majority 29.32%) of articles were from the United States of America (USA). USA, United Kingdom and Japan were the top three publishing countries. Most of the articles were in the area of medicine [n =2896(66.4%)] and nursing [n=1903(43.63%)]. The highest number of articles on PUs were published in the journals of Ostomy Wound Management (n=177), Journal of Wound Care (n=156), International Wound Journal (n=144), Journal of Wound Ostomy And Continence Nursing (n=141) and Journal of Tissue Viability (n=126). Conclusions: As the number of immobile and debiliated patients increase globally, the publications on PUs seem to be increase too. Studies outside of Europe and the USA should also be supported and the number of publications should be increased, especially from developing countries.