A framework that assigns CT examinations into broad categories based on body region and image quality requirements simplifies assessment of radiation dose for benchmarking and for developing CT pro... Background Lack of standardization in CT protocol choice contributes to radiation dose variation. Purpose To create a framework to assess radiation doses within broad CT categories defined accordin...

Background: Around 1 in 59 individuals is diagnosed with Autism Spectrum Disorder (ASD), according to CDS statistics. Conventionally, ASD has been diagnosed using functional brain regions, regions of interest, or multi-tissue-based training in artificial intelligence models. The objective of the exhibit study is to develop an efficient deep learning network for identifying ASD using structural magnetic resonance imaging (MRI)-based brain scans. Methods: In this work, we developed a VGG-based deep learning network capable of diagnosing autism using whole brain gray matter (GM) tissues. We trained our deep network with 132 MRI T1 images from normal controls and 140 MRI T1 images from ASD patients sourced from the Autism Brain Imaging Data Exchange (ABIDE) dataset. Results: The number of participants in both ASD and normal control (CN) subject groups was not statistically different (p = 0.23). The mean age of the CN subject group was 14.62 years (standard deviation: 4.34), and the ASD group had mean age of 14.89 years (standard deviation: 4.29). Our deep learning model accomplished a training accuracy of 97% and a validation accuracy of 96% over 50 epochs without overfitting. Conclusions: To the best of our knowledge, this is the first study to use GM tissue alone for diagnosing ASD using VGG-Net.

Intracardiac metastasis of the testicular cancer is very rare phenomenon. A 30-year-old-man with a history of testicular rhabdomyosarcoma and lung metastases was found to have an intracardiac filling defect in a surveillance computed tomography scan 3 years after the initial diagnosis. A cardiac magnetic resonance imaging study was performed for further evaluation and demonstrated a lobulated, heterogeneously enhancing mobile mass within the right ventricle attaching to the anterior papillary muscle. Patient underwent an open surgical resection of the cardiac mass that was confirmed metastasis of testicular rhabdomyosarcoma into the right ventricular papillary muscle and tricuspid valve. To our knowledge, this is the first report in the literature that describes metastasis to a papillary muscle and tricuspid valve from a testicular neoplasm.

Unilateral absence of pulmonary artery is a rare developmental anomaly. Infrahepatic inferior vena cava interruption is a well-recognized but uncommon developmental anomaly. Presence of both these anomalies in a single individual is extremely rare. A 58-year-old man with a history of recurrent lower extremity deep vein thrombosis and venous insufficiency presented to our emergency department with bilateral calf pain and swelling. Ultrasound demonstrated extensive deep vein thrombosis throughout bilateral lower extremities. Computed tomography angiography showed smooth tapering of the right pulmonary artery with absent distal most segment. To our knowledge, there is only 1 case report in the literature so far with both the abnormalities present in a single individual.

Extramedullary relapse of acute myeloid leukemia (AML) refers to the infiltration of leukemic cells into tissues outside the bone marrow and is a rare occurrence involving central nervous system, particularly following allogeneic stem cell transplantation. We report a rare case of extramedullary relapse of acute myeloid leukemia (AML) presenting as a thoracic epidural mass with additional multiple vertebrae and acetabular leukemic involvement in a 28-year-old male, two years postallogeneic stem cell transplantation. The patient presented with progressive lower extremity weakness and paresthesia. Imaging revealed an extensive epidural mass causing spinal cord compression, along with increased 18F-fluorodeoxyglucose uptake in the mass, multiple vertebrae and the left acetabulum. Surgical decompression and biopsy of the spinal epidural mass confirmed leukemic infiltration. To our knowledge, this is the first reported case of extramedullary AML relapses simultaneously involving the epidural space, multiple vertebrae and acetabulum.