Using LULC change detection analysis, it is possible to identify changes due to urbanization, deforestation, or a natural disaster in an area. As population growth and urbanization increase, real-time solutions for the effects of urbanization on land use are required to assess its implications for food security and livelihood. This study seeks to identify and quantify recent LULC changes in Limbe, Cameroon, and to measure rates of conversion between agricultural, forest, and urban lands between 1986 and 2020 using remote sensing and GIS. Also, there is a deficiency of research employing these data to evaluate the efficiency of LULC satellite data and a lack of awareness by local stakeholders regarding the impact on LULC change. The changes were identified in four classes utilizing maximum supervised classification in ENVI and ArcGIS environments. The classification result reveals that the 2020 image has the highest overall accuracy of 94.6 while the 2002 image has an overall accuracy of 89.2%. The overall gain for agriculture was approximately 4.6 km², urban had an overall gain of nearly 12.7 km², while the overall loss for forest was −16.9 km² during this period. Much of the land area previously occupied by forest is declining as pressures for urban areas and new settlements increase. This study’s findings have significant policy implications for sustainable land use and food security. It also provides a spatial method for monitoring LULC variations that can be used as a framework by stakeholders who are interested in environmentally conscious development and sustainable land use practices.