Increasing concern over climate change has made Carbon Capture and Storage (CCS) an important tool. Operators use deep geologic reservoirs as a form of favorable geological storage for long-term CO₂ sequestration. However, the success of CCS hinges on the integrity of wells penetrating these formations, particularly legacy wells, which often exhibit significant uncertainties regarding cement tops in the annular space between the casing and formation, especially around or below the primary seal. Misalignment of cement plugs with the primary seal increases the risk of CO₂ migrating beyond the seal, potentially creating pathways for fluid flow into upper formations, including underground sources of drinking water (USDW). These wells may not be leaking but might fail to meet the legal requirements of some federal and state agencies such as the Environmental Protection Agency (EPA), Railroad Commission of Texas (RRC), California CalGEM, and Pennsylvania DEP. This review evaluates the impact of CO₂ exposure on cement and casing integrity including the fluid transport mechanisms, fracture behaviors, and operational stresses such as cyclic loading. Findings revealed that slow fluid circulation and confining pressure, primarily from overburden stress, promote self-sealing through mineral precipitation and elastic crack closure, enhancing well integrity. Sustained casing pressure can be a good indicator of well integrity status. While full-physics models provide accurate leakage prediction, surrogate models offer faster results as risk assessment tools. Comprehensive data collection on wellbore conditions, cement and casing properties, and environmental factors is essential to enhance predictive models, refine risk assessments, and develop effective remediation strategies for the long-term success of CCS projects.

Nanobubbles (NBs) are emerging as a promising area of research across multiple scientific and industrial domains due to their unique physicochemical characteristics. NBs exhibit distinctive properties compared to normal bubbles, including high internal pressure, a large specific surface area, high interfacial activity, and long-term stability in liquids. Therefore, NBs have gained increasing attention as a novel enhanced oil recovery (EOR) technique, offering potential advantages over traditional gas flooding and chemical flooding. CO₂-NB specifically represents a particularly promising approach as an intersection of EOR and carbon capture, utilization, and storage (CCUS), as CO₂-NB enables hydrocarbon recovery and in situ CO₂ utilization and storage at reservoir conditions. This paper presents a structured comparative discussion of currently identified experimental EOR studies that employ CO₂-NBs. Based on the observations of these experiments, this paper discusses the proposed mechanisms in those experiments or other studies that could scientifically play a role in achieving incremental recovery. The main mechanisms discussed include interfacial tension reduction, wettability alteration, CO₂ transfer from NBs into the oil liquid phase, and suppression of gravity segregation. Other possible contributors discussed in the literature include buoyancy-assisted mobilization, induced shock waves, and drag force reduction. These mechanisms are examined in relation to the distinctive properties of CO₂-NBs, showing how these properties contribute to the occurrence of the proposed mechanisms, showcasing the potential of CO₂-NBs as an emergent EOR–CCUS technology. A preliminary probabilistic assessment was performed to estimate CO₂ storage potential during CO₂-NBs EOR injection. The results suggest that the majority of the injected CO₂ is dissolved in the saturated liquid phase, while the amount of free NBs is negligible, indicating that CO₂-NB injection may provide secure storage through solubility trapping, but with lower storage capacity compared to conventional geological sequestration in saline aquifers.