Serpentine supravenous hyperpigmentation (SSH) is a unique type of chemotherapy‐associated drug eruption, characterized by hyperpigmentation along the superficial venous network. Histopathology reveals an increase in melanin production without destruction of basal cells of the epidermis or dermal inflammatory infiltrate. Herein we describe a patient who developed SSH after repeated intravenous infusions with carboplatin and vinorelbine; two medications which have been uncommonly reported in association with SHH previously.

Introduction: Ingrown nail is a condition caused by the perforation of the periungual soft tissues on nail folds by the sides of nail plaque, causing inflammation and severe pain. Recently, the role of foot anatomical disorders in ingrown nail development has been emphasized. Objectives: The main objective of this study aimed to determine whether foot deformities played significant roles in ingrown nail development with objective radiological parameters. Methods: The study included 64 patients diagnosed with clinical ingrown nail and 71 patients as controls without any ingrown nail history. In both groups, we evaluated the bilateral foot radiographs of patients with ingrown nails for hallux valgus angle (HVA), interphalangeal angle (IPA), and intermetatarsal angle (IMA) associated with hallux valgus, and the calcaneal pitch angle (CPA), talohorizontal angle (THA), and talometatarsal angle (TMA) related to pes planus. Results: No significant difference was found in terms of hallux valgus radiological measurements of HVA, IPA and IMA as well as pes planus radiological measurements of CPA and TMA values, when compared to controls. THA was statistically significantly higher in the control group (P = 0.025). There was a moderate strength positive relationship between ingrown nail stage and measured TMA for pes planus diagnosis (rho = 0.326; P = 0.04), yet there are no significant correlations between ingrown nail stage and other angles. Conclusions: Therefore, we do not recommend foot anatomy correction in the prevention and treatment of ingrown nails, unless there is an accompanying foot deformity; however, pes planus is a foot deformity that can accompany patients with severely ingrown nails.

Gilbert's syndrome is a hereditary and benign disorder characterized by intermittent nonconjugated hyperbilirubinemia. A twenty‐three‐ year‐old patient with Gilbert syndrome and moderate acne vulgaris was started on isotretinoin at a dose of 20 mg/day. One month later, serum bilirubin levels were found to be significantly lower than that of the baseline levels. Recent studies in the literature also support that bilirubin levels tend to decrease in patients with Gilbert syndrome under oral isotretinoin therapy.

Introductıon: Scabies is a contagious, infectious skin disease that is observed worldwide. Scabies affects individuals of all ages, although it exhibits significant differences between childhood and adulthood. While publications documenting the co-occurrence of anxiety, depression, and impaired quality of life in adult patients with scabies are increasing, the presence of these issues in pediatric patients remains a topic of curiosity. Objectıves: In this study, we aimed to investigate the presence of sleep disorders, quality of life, anxiety, and depression in children with scabies. Methods: In this analytical case-control study, 68 scabies patients and 69 healthy controls aged between 6 and 17 years were included. Results: In patients with scabies, sleep quality was significantly poorer compared to the control group (p<0.001). There was no difference between the 2 groups in terms of RCADS (Revised Children's Anxiety and Depression Scale) and total anxiety and depression scores. In the control group, the number of individuals with upper and upper-middle socioeconomic levels was higher (p=0.036). A moderate correlation was found between impairment in dermatology-related quality of life and deterioration in sleep quality in patients with scabies (r=0.606, p<0.001). Conclusıon: This study found that sleep disorders are common among children diagnosed with scabies, negatively impacting their quality of life compared to healthy controls. We believe that obtaining information about both night and day sleep patterns during dermatological follow-ups of children diagnosed with scabies, and providing recommendations on sleep hygiene as part of the treatment process, may have positive effects on a child’s quality of life.

Based on the presence of chronic pain and the potential use of common treatment agents in Notalgia Paresthetica (NP) and Fibromyalgia Syndrome (FMS) for improvement, we aimed to investigate the frequency of FMS symptoms in NP patients and its impact on quality of life. This study is a case control cohort study including 26 patients diagnosed with NP and a total of 26 controls matched for age and gender. The 2016 revised fibromyalgia diagnostic criteria by the American College of Rheumatology (ACR) were used to inquire about FMS diagnosis criteria in the study. According to the 2016 ACR revised FMS diagnostic criteria, the frequency of FMS was significantly higher in the patient group (n = 9, 34.6%) compared to the control group (n = 2, 7.7%) (p = 0.042). The Wide Pain Index (WPI) score in the control group was 2.00 (3.25), while in the patient group, it was 4.00 (8.00), with a statistically significant difference between them (p < 0.035). Furthermore, significant statistical differences were found between the two groups in terms of Symptom Severity Scale (SSS), Fibromyalgia Score (FS), and FIQ (p < 0.035, p < 0.001, p < 0.001, respectively). In NP patients with accompanying FMS, Dermatology Life Quality Index was significantly more affected compared to those without FMS (p = 0.025). In conclusion, we recommend that NP patients be questioned about FMS, which is characterized by generalized pain, as well as regional neuropathic symptoms. Treatment success can be enhanced by using common agents in the treatment choice for accompanying FMS.

Androgenetic alopecia (AGA) is one of the most common types of hair loss. Histopathological evidence of chronic inflammation in patients with AGA has prompted investigations into the potential increased cardiovascular risk. This study aimed to investigate the presence of cardiovascular risk factors and potential conduction disorders in male patients diagnosed with AGA using both echocardiographic (ECHO) and electrocardiographic (ECG) assessments. This case -control study included 40 male patients diagnosed with AGA and 40 male controls, aged between 18 and 50 years. All participants in both groups underwent comprehensive cardiological examination by a specialist cardiologist and were evaluated using ECG and ECHO. Examination of ECG parameters showed that P-wave dispersion (Pdis) was significantly higher in the patient group ( P = .016). Additionally, the shortest and corrected QT interval (QTc min) was significantly lower in the patient group than in the control group ( P = .031). No significant difference was found between the patient and control groups in terms of ECO measurements (all P >.05). There was a moderately positive correlation between disease duration and Pdis ( r = .365) and between disease stage and Pmax, Pdis, QTc min, and QTc max ( r = .490, r = .499, r = .445, and r = .432, respectively). This study concluded that male patients with AGA exhibited an increased risk of developing arrhythmias, as indicated by elevated Pdis and reduced QTc min values. In this context, ECG may serve as a useful screening tool for conduction abnormalities in male with AGA. We suggest that patients with AGA may benefit from closer cardiac monitoring and cardiology consultations, especially regarding rhythm disorders.