Sinem Akgül

Dr. Sinem Akgül


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 February 2023 in Materials
Verified
Journal Article
Open access
PDF file
HAHanife Altınışık
Hanife Altınışık
SASinem Akgül
Sinem Akgül
MNMerve Nezir
Merve Nezir
SÖSuat Özcan
Suat Özcan
EÖEsra Özyurt
Esra Özyurt
The aim of this study is to evaluate the effectiveness of in-office bleaching in esthetic dentistry on the roughness and color stability of the enamel surface, using different concentrations of hydrogen peroxide (HP). Fifty human incisors were randomly divided into 5 groups (n = 10). No bleaching was performed in the control group. For these groups, concentrations of 40% HP with fluoride (F), 35% HP with calcium (Ca), 25% HP with nano-hydroxyapatite (nHA) and 18% HP with nHA were used for bleaching in the test groups. Surface roughness was assessed at baseline after bleaching occurred. Color measurements were first obtained at baseline, then after the first and second sessions of bleaching, and, finally, after the staining protocol. Scanning electron microscopy and atomic force microscopy were performed. Statistical analysis was conducted with a one-way ANOVA, followed by a post hoc Tukey’s test and a paired-samples t-test (p < 0.05). All the bleaching gels used exhibited a similar color change (p > 0.05). Bleaching gels containing 18% HP with nHA and that containing 35% HP with Ca caused less surface roughness of the enamel. Of these concentrations, 25% HP with nHA caused the most surface roughness and no significant difference was observed, compared with 40% HP with F. The highest coloration after bleaching was observed in 40% HP with F and 25% HP with nHA. The lowest coloration was obtained in 35% HP with Ca and 18% HP with nHA but no significant difference was observed between them and the control group. A concentration above 18% HP does not increase the bleaching effectiveness. The results show that 18% HP with nHA and 35% HP with Ca resulted in the least increase in enamel surface roughness when compared to high-concentrate HP; however, it also prevented recoloration after bleaching.

26 July 2021 in European Journal of Oral Sciences
Verified
Journal Article
Closed access
PDF file
SASinem Akgül
Sinem Akgül
CACemile Kedici Alp
Cemile Kedici Alp
BBBala Bala
Bala Bala


25 February 2025 in BMC Oral Health
Verified
Journal Article
Open access
PDF file
CSCeyda SARI
Ceyda SARI
BBBala Bala
Bala Bala
SASinem Akgül
Sinem Akgül
CACemile Kedici Alp
Cemile Kedici Alp
This study aimed to evaluate the effects of different restorative techniques and materials on cuspal deflection and microleakage in MOD restorations. Eight groups were tested using incremental and bulk-fill techniques, with or without fiber reinforcement. The restorative materials included Filtek Z250 and Filtek Bulk-fill Posterior, while reinforcement materials such as Interlig glass fiber, EverX Posterior, and Surefill SDR were incorporated to assess their impact. In total, 96 freshly extracted, sound human maxillary first premolars were selected and stored in 0.1% thymol solution at 37 °C. The teeth were randomly assigned into eight groups (n = 12). Standardized MOD cavities were prepared, followed by endodontic treatment and sealing with glass ionomer cement. The groups were as follows: Group 1—Filtek Z250 applied incrementally in 2-mm layers; Group 2—U-shaped Interlig glass fiber followed by incremental Filtek Z250; Group 3—Filtek Bulk-fill Posterior using the bulk technique; Group 4—U-shaped Interlig glass fiber followed by Filtek Bulk-fill Posterior; Group 5—EverX Posterior followed by incremental Filtek Z250; Group 6—EverX Posterior followed by Filtek Bulk-fill Posterior; Group 7—Surefill SDR followed by incremental Filtek Z250; and Group 8—Surefill SDR followed by Filtek Bulk-fill Posterior. Cuspal deflection was measured using a digital micrometer with 0.05 μm precision. Microleakage was assessed using a 0.5% basic fuchsin dye solution at 37 °C for 24 h, followed by sectioning and examination under magnification. The lowest mean cuspal deflection was observed in Group 2 (15.8 μm), while the highest was in Group 5 (27.2 μm). Statistically significant differences were observed in cuspal deflection across the groups and over time (p < 0.05). Significant differences in microleakage scores were also found among the groups, indicating the impact of restorative materials and techniques on these outcomes (p < 0.05). This study demonstrated that Filtek Z250 and Filtek Bulk-fill Posterior showed different effects on cuspal deflection and microleakage. The use of glass fiber and EverX Posterior improved restoration performance by reducing polymerization effects. Surefill SDR also reduced cuspal deflection due to its low polymerization shrinkage. Clinically, selecting the appropriate restorative materials and techniques based on the extent of tooth structure loss can improve long-term outcomes.

13 November 2024 in BMC Oral Health
Verified
Journal Article
Open access
PDF file
CSCeyda SARI
Ceyda SARI
SASinem Akgül
Sinem Akgül
BBBala Bala
Bala Bala
Composite restorations often have gingival margins near the cemento-enamel junction (CEJ), where the microleakage of these margins can significantly contribute to the restoration failure, especially in the cervical lesions. It is important to determine the microleakage is crucial, as it typically occurs through the interfacial gap between the tooth and the restoration. Various resin composites and techniques have been developed to minimize this gap and reduce the risk of microleakage. The aim of this in vitro study was to evaluate the levels of microleakage of different modes of a universal adhesive and two novel resin composites in restoring class V cavities in the central incisors. Sixty-six freshly extracted sound human central incisors of the similar size were randomly assigned to 2 groups (n = 33 per group) according to the brand of resin composite. Each group was further divided into 3 subgroups based on the Scotch Bond Universal (3 M ESPE, Saint Paul, MN, USA) application protocol used: (a) total etch, (b) self-etch and (c) selective etch. After composite restoration completed with Omnichroma (Tokuyama Dental Corp., Tokyo, Japan) and Filtek Universal Restorative (3 M ESPE, Saint Paul, MN, USA), each tooth was immersed in a 0.5% basic fuchsin dye solution at 37C0 for 24 h. After dye penetration, teeth were sectioned and evaluated with conventional (scoring) and digital methods (ImageJ). The intra- and inter-examiner agreement was estimated according to the Kappa statistics and the results were analyzed with the one-way ANNOVA and the Kruskal–Wallis test (p < 0.05). The rates of microleakage of the gingival and incisal margins are statistically similar, regardless of the composite brand and the method of application of the universal adhesive. The microleakage exhibited by current adhesives and resins is independent of the adhesive application mode and measurement method.

2 July 2025 in BMC Oral Health
Verified
Journal Article
Open access
PDF file
ABAyşenur Bulut
Ayşenur Bulut
OBOya Bala
Oya Bala
CSCeyda Sari
Ceyda Sari
SASinem Akgül
Sinem Akgül
The aim was to examine the effect of three polishing systems (TwistDia, SuperSnap, and Opti 1Step) and additional polishing on the surface roughness and color change of two universal resin composites (OptiShade and Omnichroma) immersed in coffee. A total of 80 samples were prepared, 40 samples for each of the resin composites (n:10). For the control group no polishing step was applied. Other samples were polished using Twist Dia, Opti 1Step, or SuperSnap. The baseline (T0) surface roughness and color parameters of the samples were measured. After the samples were immersed in coffee for 12 days (T1), and after the surface of the samples was polished, each sample were measured (T2). In both universal resin composites, the lowest surface roughness values were obtained from the control group (p < 0.05). The highest surface roughness values were observed in the group polished with SuperSnap of OptiShade resin, both after immersed in coffee and after additional polishing(p < 0.05). İt was observed that samples prepared with OptiShade resin composite samples generally showed lower ΔE values compared than the other resin composites. Additional polishing applications, caused changes in color parameters and increases in surface roughness in single shade resin composites, although not statistically significant.