This article presents the results of the Innovation Support Program (ISP), designed to enhance the market readiness of 12 bio-based innovators from six European rural regions: Northern Sweden, Mazovia (Poland), Upper Austria, Pays de la Loire (France), Strumica (Macedonia), and Andalusia (Spain). Over three years, the ISP applied a modular and flexible methodology, beginning with a cross-regional needs analysis to identify knowledge gaps, followed by a call for Expressions of Interest to select promising bio-based solutions, and concluding with tailored support delivered through regional Task Forces. These provided mentoring and capacity-building activities focusing on business modeling, market analysis, and funding opportunities. The program identified market access as a major barrier to scaling up and noted that many solutions followed Social and Solidarity Economy principles, prioritizing social and environmental impact over profit. Through targeted assistance and knowledge exchange, the ISP strengthened local innovation capacity and contributed measurable progress in companies’ Technology Readiness Levels (TRLs) and Key Performance Indicators (KPIs). Positioned within the framework of the EU Bioeconomy Strategy, the ISP demonstrates how combining regional insights with a structured support framework can effectively accelerate the scaling of bio-based solutions, highlighting the need for iterative, long-term support to sustain regional bioeconomy growth.

The development of mineral, biodegradable sunscreens that can offer both high photoprotection and long-term colloidal stability, while limiting synthetic additives, presents a significant challenge. A linseed-oil nanoemulsion co-stabilised by ZnO nanoparticles and the eco-friendly surfactant Appyclean 6552 was formulated, and the effect of incorporating fumed silica/alumina (Aerosil COK 84) was evaluated. A central composite response surface design was used to ascertain the oil/ZnO ratio that maximized the in vitro sun protection factor at sub-300 nm droplet size. The incorporation of Aerosil at concentrations ranging from 0 to 2 wt.% resulted in a transformation of the dispersion from a nearly Newtonian state to a weak-gel behavior. This alteration was accompanied by a reduction in the Turbiscan Stability Index. Microscopic analysis has revealed a hierarchical particle architecture, in which ZnO forms Pickering shells around each droplet, while Aerosil aggregates bridge neighboring interfaces, creating a percolated silica scaffold that immobilizes droplets and amplifies multiple UV scattering. The findings demonstrate that coupling interfacial Pickering armor with a continuous silica network yields a greener, physically robust mineral sunscreen and offers a transferable strategy for stabilizing plant-oil emulsions containing inorganic actives.

The development of mineral, biodegradable sunscreens that can offer both high photoprotection and long-term colloidal stability, while limiting synthetic additives, presents a significant challenge. A linseed oil nanoemulsion co-stabilised by ZnO nanoparticles and the eco-friendly surfactant Appyclean 6552 was formulated, and the effect of incorporating fumed silica/alumina (Aerosil COK 84) was evaluated. A central composite response surface design was used to ascertain the oil/ZnO ratio that maximised the in vitro sun protection factor at sub-300 nm droplet size. The incorporation of Aerosil at concentrations ranging from 0 to 2 wt.% resulted in a transformation of the dispersion from a nearly Newtonian state to a weak-gel behaviour. This alteration was accompanied by a reduction in the Turbiscan Stability Index. Microscopic analysis has revealed a hierarchical particle architecture, in which ZnO forms Pickering shells around each droplet, while Aerosil aggregates bridge neighboring interfaces, creating a percolated silica scaffold that immobilises droplets and amplifies multiple UV scattering. The findings demonstrate that coupling interfacial Pickering armour with a continuous silica network yields a greener, physically robust mineral sunscreen and offers a transferable strategy for stabilising plant-oil emulsions containing inorganic actives.