Ruchi Rakesh Khobragade

Ms. Ruchi Rakesh Khobragade


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 August 2025 in Pharmaceutics
Verified
Journal Article
Open access
PDF file
RKRuchi Rakesh Khobragade
Ruchi Rakesh Khobragade
ACAnis Ahmad Chaudhary
Anis Ahmad Chaudhary
MAMohamed Ali
Mohamed Ali
MKMayur Bhimrao Kale
Mayur Bhimrao Kale
NRNeha S. Raut
Neha S. Raut
RTRashmi Kishoritai Bhoyar College of Trivedi
Rashmi Kishoritai Bhoyar College of Trivedi
Sunscreen protects skin from harmful Ultra Violet (UV) rays, preventing skin diseases like cancer and premature aging. This review explores the role of nanotechnology in enhancing sunscreen formulations by incorporating green and sustainable ingredients. Nanoparticles such as titanium dioxide and zinc oxide effectively reflect UV rays, improving protection while minimizing white residue, thereby enhancing aesthetics, stability, and efficacy. Recent advancements in formulation include lipid-based and polymer-based nanosystems that improve the delivery of active ingredients, offering multifunctional benefits. Additionally, modern sunscreens integrate anti-aging and antioxidant properties, reflecting the trend toward hybrid formulations with multiple skin benefits. The review also examines recent patents, highlighting innovations in nanotechnology-driven sunscreen formulations and delivery systems. Safety and regulatory concerns are critically analyzed, focusing on public perception of nanoparticles and their environmental impact. Issues such as manufacturing challenges and consumer hesitancy toward nano-scaled formulations due to safety considerations are also discussed. While nanotechnology presents significant potential in advancing sun protection, the review underscores the importance of balancing innovation with safety and sustainability. Ultimately, it serves as a guide for future research directions in nano-based sunscreens, advocating for responsible and informed development in the field.

10 April 2026 in Pathogens
Verified
Journal Article
Open access
PDF file
NRNeha S. Raut
Neha S. Raut
ACAnis Ahmad Chaudhary
Anis Ahmad Chaudhary
HPHarshad Patil
Harshad Patil
SSSupriya Shidhaye
Supriya Shidhaye
RKRuchi Rakesh Khobragade
Ruchi Rakesh Khobragade
RTRashmi Kishoritai Bhoyar College of Trivedi
Rashmi Kishoritai Bhoyar College of Trivedi
Background/Objectives: Antimicrobial resistance (AMR) is a critical global public health challenge driven by inappropriate and excessive antimicrobial use (AMU) across human, animal, and environmental sectors. Method: This narrative review synthesizes recent evidence on antimicrobial utilization and resistance patterns. A structured search of PubMed, Scopus, and Web of Science was conducted for studies published between 2015 and 2025. Eligible sources included surveillance reports, registry-based analyses, and clinical studies. Data were qualitatively analyzed to identify key trends and regional variations. Result: Marked geographical variation in AMR was observed. Carbapenem resistance in Escherichia coli remains low globally (2–3%) but is higher in Southeast Asia (17–18%) and India (~40%). Klebsiella pneumoniae shows consistently high resistance (>40% globally; ~54% in India), while Pseudomonas aeruginosa exhibits stable resistance levels (35–45%). Resistance prevalence increases from primary to tertiary care settings, reflecting greater antimicrobial exposure. Vulnerable populations—including pediatric, elderly, pregnant, and immunocompromised patients—face higher risks of antimicrobial exposure and adverse outcomes, including nephrotoxicity, hepatotoxicity, and microbiome disruption. WHO AWaRe data indicate a global shift toward increased use of Watch-category antibiotics. Stewardship interventions, such as audit and feedback, prescribing restrictions, rapid diagnostics, and decision support systems, effectively reduce inappropriate AMU. Conclusions: Integrated, data-driven antimicrobial stewardship and robust surveillance systems are essential to mitigate the global burden of AMR.