Pablo del Villar-Guerra

Dr. Pablo del Villar-Guerra


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 September 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
AMAlberto Medina
Alberto Medina
PVPablo del Villar-Guerra
Pablo del Villar-Guerra
JOJUAN RAMON VALLE ORTIZ
JUAN RAMON VALLE ORTIZ
VAVicent Modesto i Alapont
Vicent Modesto i Alapont
The concept of mechanical power (MP) has emerged as a comprehensive indicator of ventilator-induced lung injury (VILI). It integrates the effects of tidal volume, airway pressures, respiratory rate, and flow. However, applying MP as a universal threshold (e.g., 12 J/min) across heterogeneous patients with acute respiratory distress syndrome (ARDS) may be inadequate. This review introduces the rheological model, which conceptualizes the lung as a viscoelastic body (i.e., one that exhibits both elastic and viscous properties), and applies it to ARDS ventilation. The rheological model may offer individualized MP thresholds. The potential benefits of adjusting MP based on ideal body weight (J/min/kg) are discussed and, more accurately, on static compliance (J/min/L). Static compliance could better reflect functional lung size, though clinical validation remains needed. Preliminary clinical and modeling evidence suggests that normalized MP correlates more closely with mortality than absolute MP and aligns with pulmonary stress–strain behavior. This normalization provides a more precise risk stratification and facilitates the easier setting of ventilation targets, particularly in patients with low compliance or abnormal body composition. This review clarifies definitions and consolidates evidence, highlights the clinical implications of rheology for lung-protective strategies. MP normalization within a lung-protective strategy could enhance the safety and efficacy of mechanical ventilation; however, clinical validation is still required. This review summarizes the theoretical foundations, supporting evidence, and clinical implications of this approach within the broader context of rheological modeling in ARDS.

27 April 2022 in Anales del Sistema Sanitario de Navarra
Verified
Journal Article
Open access
LCL. García-Trevijano Cabetas
L. García-Trevijano Cabetas
PVPablo del Villar-Guerra
Pablo del Villar-Guerra
LRL. Lozano Rincón
L. Lozano Rincón
AGA. Cano Garcinuño
A. Cano Garcinuño
Se describen las características de los pacientes susceptibles de cuidados paliativos pediátricos (CPP) de un hospital de segundo nivel, así como la frecuencia de visitas a urgencias, de ingresos y de dispositivos tecnológicos empleados.

18 April 2022 in Anales de Pediatría (English Edition)
Verified
Journal Article
Open access
PVPablo del Villar-Guerra
Pablo del Villar-Guerra
AFAna Martínez Flórez
Ana Martínez Flórez
CFCristina Catalina Fernández
Cristina Catalina Fernández
RCRamón Cancho Candela
Ramón Cancho Candela
FMFernando Centeno Malfaz
Fernando Centeno Malfaz

2 May 2026 in Anales de Pediatría (English Edition)
Verified
Journal Article
Open access
PBPatricia Musgo Balana
Patricia Musgo Balana
CMClaudia Rondón Martínez
Claudia Rondón Martínez
BFBelén Valles Fernández
Belén Valles Fernández
PVPablo del Villar-Guerra
Pablo del Villar-Guerra

1 May 2022 in Anales de Pediatría
Verified
Journal Article
Open access
PVPablo del Villar-Guerra
Pablo del Villar-Guerra
AFAna Martínez Flórez
Ana Martínez Flórez
CFCristina Catalina Fernández
Cristina Catalina Fernández
RCRamón Cancho Candela
Ramón Cancho Candela
FMFernando Centeno Malfaz
Fernando Centeno Malfaz

4 August 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
AMAlberto Medina
Alberto Medina
PVPablo del Villar-Guerra
Pablo del Villar-Guerra
JOJuan Ramón Valle Ortiz
Juan Ramón Valle Ortiz
VAVicent Modesto i Alapont
Vicent Modesto i Alapont
The concept of mechanical power (MP) has emerged as a comprehensive indicator of ventilator-induced lung injury (VILI), integrating the effects of tidal volume, airway pressures, respiratory rate, and flow. However, applying MP as an absolute threshold (e.g., 12 J/min) across heterogeneous patients with acute respiratory distress syndrome (ARDS) may be inadequate. This article explores a rheological model for the respiratory system that reconceptualizes the lung as a viscoelastic body and advocates for individualized MP thresholds. We propose adjusting MP based on ideal body weight (J/min/kg) and, more accurately, on static compliance (J/min/L), which better reflects functional lung size ("baby lung") and mechanical vulnerability. This normalization offers a more precise risk stratification and easier setting of ventilation targets, particularly in patients with low compliance or abnormal body composition. Emerging evidence suggests that normalized MP correlates more closely with mortality than absolute MP values and aligns with the physiological stress-strain behavior of pulmonary tissue. Adopting MP normalization within lung-protective strategies could enhance the safety and efficacy of mechanical ventilation, however clinical validation is still required. This review summarizes the theoretical foundations, supporting evidence, and clinical implications of this approach within the broader context of rheological modeling in ARDS.