Tunahan Akyol

Dr. Tunahan Akyol

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 December 2025 in International Journal of Sexual Science
Verified
Journal Article
Open access
TATunahan Akyol
Tunahan Akyol
EUEmine Seker Un
Emine Seker Un
OPOsman PARCA
Osman PARCA
GAGizem Kavas Akyol
Gizem Kavas Akyol
Objective: To evaluate postoperative changes in male sexual function after cataract surgery and to examine the association between improvements in visual acuity and sexual performance using the International Index of Erectile Function (IIEF). Material and Methods: This prospective observational study included 52 men with age-related cataract who underwent uncomplicated phacoemulsification and intraocular lens implantation. Sexual function was assessed using the IIEF, encompassing erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction. Assessments were conducted preoperatively and one month postoperatively. Best-corrected visual acuity (BCVA) and demographic data were also recorded. Paired Student’s t-test was used to compare pre- and postoperative results. Results: The mean BCVA improved significantly from 0.58 ± 0.21 logMAR preoperatively to 0.14 ± 0.09 logMAR at one month (p < 0.001). Total IIEF scores increased from 35 ± 1.6 to 43 ± 1.7 (p < 0.005), indicating overall enhancement in sexual function. Significant improvements were observed in orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction (p < 0.005 for all), while changes in erectile function were not statistically significant (p > 0.05). Visual improvement correlated positively with changes in total IIEF score (r = 0.52, p = 0.001). Conclusion: Cataract surgery not only restores vision but also positively influences sexual and psychosocial well-being. Improvements in sexual satisfaction, desire, and orgasmic function highlight the broader quality-of-life benefits of visual rehabilitation. Further large-scale studies are needed to clarify the mechanisms underlying this association.

Verified
Journal Article
Open access
PDF file
TATunahan Akyol
Tunahan Akyol
OPOsman PARCA
Osman PARCA
EUEmine Seker Un
Emine Seker Un
ITIbrahim Toprak
Ibrahim Toprak
GPGokhan Pekel
Gokhan Pekel
Background/Objectives: To evaluate early postoperative changes in scleral and iris thicknesses together with corneal layer thicknesses and tomographic parameters following corneal collagen cross-linking (CXL) in eyes with progressive keratoconus. Methods: This retrospective study included 94 eyes of 94 patients with progressive keratoconus who underwent standard epithelium-off CXL using the Dresden protocol. Corneal tomography (Pentacam) and anterior segment optical coherence tomography (AS-OCT) measurements were obtained preoperatively and at the early postoperative follow-up (3 months ± 2 weeks). Thickness measurements of the tear film, corneal epithelium, Bowman layer, stroma, Descemet–endothelium complex, sclera (1–3 mm from the limbus), and iris (1–2 mm from the pupillary margin) were analyzed. Pre- and post-CXL values were compared using paired statistical tests, and effect sizes were calculated. Results: In the early postoperative period, scleral thickness showed a significant increase at all measured distances from the limbus, with medium effect sizes, while iris thickness demonstrated a significant decrease at all measurement points with large effect sizes (p < 0.001). Tear film, epithelial, and stromal thicknesses decreased significantly after CXL, whereas Bowman layer and Descemet–endothelium complex thicknesses remained unchanged. Pachymetric measurements revealed significant thinning at the pupil center, corneal apex, and thinnest point. No significant changes were observed in Kmax or anterior chamber depth, indicating stabilization rather than progression in the early postoperative period. Conclusions: Corneal collagen cross-linking was associated with measurable early structural changes in corneal layers and extra-corneal anterior segment tissues during the postoperative period. The observed increase in scleral thickness and decrease in iris thickness suggest that structural alterations may occur in extra-corneal anterior segment tissues following CXL. These findings support the concept that CXL influences anterior segment biomechanics in a tissue-specific manner and that extra-corneal parameters may serve as complementary markers for early postoperative assessment.

16 September 2026 in Archives of Current Medical Research
Verified
Journal Article
Closed access
OPOsman PARCA
Osman PARCA
TATunahan Akyol
Tunahan Akyol
SGSabiha Salar Gül
Sabiha Salar Gül
EUEmine Seker Un
Emine Seker Un
Background: Demodex-associated blepharitis is a chronic inflammatory eyelid disease characterized by collarettes, eyelid margin inflammation, and the presence of Demodex mites. Comparative data on different tea tree oil (TTO)-based application forms remain limited. This study compared the clinical and microscopic outcomes of TTO-based eyelid wipes and eyelid shampoo in Demodex-positive chronic blepharitis.Methods: In this retrospective, single-center study, 155 adults with clinically and microscopically confirmed Demodex-positive chronic blepharitis were grouped by treatment form: eyelid wipes (n=74) or eyelid shampoo (n=81). Baseline and 3-month assessments included subjective symptoms, Ocular Surface Disease Index (OSDI) scores, collarette severity, eyelid margin erythema, meibum quality, meibomian gland obstruction, and microscopic Demodex status.Results: Baseline demographic and clinical characteristics were similar between groups. At 3 months, symptoms improved in both groups, but burning was less frequent in the wipe group (p=0.048). The OSDI score was lower in the wipe group (24.4±7.5 vs 27.3±8.6; p=0.026). Collarette and meibum quality scores favored the wipe group (p=0.011 and p=0.003, respectively). Meibomian gland obstruction scores were comparable (p=0.87), whereas improvement in eyelid margin erythema (89.2% vs 76.5%; p=0.038) and meibomian gland obstruction (83.8% vs 67.9%; p=0.022) was more frequent in the wipe group. Demodex eradication rates were similar (64.9% vs 60.4%; p=0.570).Conclusion: Both TTO-based formulations were associated with clinical improvement and comparable Demodex eradication. Eyelid wipes may provide additional benefit for ocular surface-related quality of life and selected eyelid margin and meibomian gland outcomes. Prospective randomized studies are needed to confirm these results.

5 May 2026 in BMC Ophthalmology
Verified
Journal Article
Open access
PDF file
EUEmine Seker Un
Emine Seker Un
TATunahan Akyol
Tunahan Akyol
OPOsman PARCA
Osman PARCA
SBSevket Oguz Belli
Sevket Oguz Belli
To compare the effects of single clear corneal incision (CCI) and opposite clear corneal incision (OCCI) techniques on corneal and total astigmatism in pat

10 October 2026 in Pamukkale Medical Journal
Verified
Journal Article
Open access
EUEmine Seker Un
Emine Seker Un
TATunahan Akyol
Tunahan Akyol
OPOsman PARCA
Osman PARCA
GPGökhan Pekel
Gökhan Pekel
ABAlperen Bahar
Alperen Bahar
SASelen Akbulut
Selen Akbulut
Purpose: To evaluate anterior segment changes induced by the Valsalva maneuver in phakic and pseudophakic eyes using Scheimpflug imaging.Materials and methods: This paired-eye cross-sectional observational study included 136 eyes of 68 patients with unilateral pseudophakia, with each participant contributing one pseudophakic eye and the contralateral phakic eye. Intraocular pressure (IOP), central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV), pupil diameter (PD), iridocorneal angle (ICA), axial length (AL), and the ACD/AL ratio were measured at baseline and during a standardized Valsalva maneuver. Measurements were obtained using non-contact tonometry, Scheimpflug imaging, and optical biometry. Within-eye changes from baseline were analyzed separately for phakic and pseudophakic eyes.Results: During the Valsalva maneuver, IOP and PD increased significantly in both phakic and pseudophakic eyes (all p≤0.003). In phakic eyes, ACD and ACV decreased significantly (both p=0.03), whereas ICA did not change significantly (p=0.58). In pseudophakic eyes, ICA decreased significantly (p=0.002), whereas the changes in ACD and ACV were not statistically significant (p=0.08 and p=0.61, respectively). No statistically significant changes were detected in AL, CV, or the ACD/AL ratio in either group. CCT changes did not reach the predefined threshold for statistical significance.Conclusions: The Valsalva maneuver was associated with transient changes in intraocular pressure, pupil diameter, and selected anterior segment parameters in both phakic and pseudophakic eyes. Within-eye analyses showed significant reductions in ACD and ACV in phakic eyes and significant narrowing of the ICA in pseudophakic eyes. However, direct comparison of these changes between lens-status groups is required before concluding that phakic and pseudophakic eyes exhibit different biomechanical responses. Standardization of respiratory effort may improve the reliability of anterior segment imaging and biometric measurements.

2 July 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
TATunahan Akyol
Tunahan Akyol
AAAvni Murat Avunduk
Avni Murat Avunduk
UYUğur Yılmaz
Uğur Yılmaz
In this study, the blood parameters of patients with age-related macular degeneration who applied to our clinic were compared with patients in a similar age range who had no additional disease and applied to our clinic for cataract surgery, and it was aimed to find a clinical preliminary diagnosis. With clinical preliminary diagnosis, it was aimed to prevent permanent vision loss in advanced age through early treatment. Between January 2010 and March 2023, 102 people who had not previously been diagnosed with age-related macular degeneration and who first applied to the retina unit of the Department of Ophthalmology at Pamukkale University or were under previous follow-up, and who applied to our hospital for cataract surgery in the same period and had no additional disease, were included in the control group. Wet type and dry type AMD patients were separated in the study and compared. All patients underwent visual acuity measurement, intraocular pressure measurement, biomicroscopic anterior and posterior segment examination, and optical coherence tomography measurement. For cases in which the distinction between dry and wet type AMD could not be definitively made, and for all wet type AMD patients, fundus fluorescein angiography was performed. In the wet type AMD patient group, at least one eye had a choroidal neovascular membrane and leakage/hemorrhage or RPE detachment related to the membrane was observed. In the dry type AMD group, at least one eye had drusen (at least >63 microns) or geographic atrophy in the macula. As a result, while it was aimed to prevent permanent vision loss in advanced age through early treatment with clinical preliminary diagnosis, we did not encounter a clear parameter to make a clinical diagnosis between the patient and control groups. After the clinical diagnosis, NLR and PLR can be used as a visual marker during the diagnosis stage to distinguish the disease type.