Nosocomial infections caused by Candida albicans pose serious challenges to healthcare systems due to their persistence on medical surfaces and resistance to conventional disinfectants. This study evaluates antifungal properties of SnO₂ doped with silver and cuprite nanoparticles and WO₃ thin films, as well as cobalt (CoFe₂O₄) and cobalt–nickel (Co_0.5Ni₀.₅Fe₂O₄) ferrite nanoparticles, activated by ultraviolet C (UVC) radiation, direct electric current (up to 100 V), and magnetic fields. SnO₂ films were synthesized by Spray Pyrolysis and WO₃ by Sputtering deposition, Ferrites nanoparticles by sol–gel, while metallic nanoparticles were synthetized via chemical reduction. Characterization consisted mainly of SEM, TEM, and XRD, and their antimicrobial activity was tested against C. albicans. WO₃ films achieved 86.2% fungal inhibition after 5 min of UVC exposure. SnO₂ films doped with nanoparticles reached 100% inhibition when combined with UVC and 100 V. Ferrite nanoparticles alone showed moderate activity (21.9%–40.4%) but exhibited strong surface adhesion to fungal cells, indicating potential for magnetically guided antifungal therapies. These results demonstrate the feasibility of using multifunctional nanomaterials for rapid, non-chemical disinfection. The materials are low-cost, scalable, and adaptable to hospital settings, making them promising candidates for reducing healthcare-associated fungal infections through advanced surface sterilization technologies.