(1) Background: Color changes, physical degradation, and fungal infections are challenges to the longevity of maxillofacial polydimethylsiloxane (PDMS) elastomers. This study aimed to evaluate color changes, physical properties, and antifungal properties of PDMS loaded with ZrO₂ and TiO₂ submicron- and nano-sized particles. (2) Methods: A 1% weight of 40 nm or 200 nm diameter ZrO₂ or TiO₂ nanoparticles was mixed into PDMS with 2% functional intrinsic yellow pigment and polymerized. Control materials contained 13% weight 200 nm silica. Samples were exposed to 3000 h of UVB radiation (200 µW/cm²) or darkness. Color parameters L*a*b* and ∆E_ab*, ultimate tensile strength, strain, elastic modulus, and Shore A hardness were measured. Candida albicans growth was measured using XTT and confocal microscopy, and data were analyzed with the Dunnett test (p < 0.01). (3) Results: TiO₂ 200 nm showed the least color change after 3000 h of UVB radiation, followed by TiO₂ 40 nm (p < 0.05). The silica-containing control group was superior in all physical property measurements due to higher additive content (p < 0.05). TiO₂-containing materials exhibited significantly lower C. albicans growth (p < 0.01) than those loaded with ZrO₂ or SiO₂. (4) Conclusions: TiO₂ nanoparticles of 40 nm and 200 nm, when added to pigmented PDMS at 1% weight, provided the best resistance to color change and significantly lowered C. albicans activity compared to silica- and zirconia-filled elastomers. Particle size differences rendered minor differences for most properties. The incorporation of low-level submicron- and nano-sized TiO₂ particles has the potential to improve color stability and antifungal activity in silicones designated for maxillofacial prostheses and may be extended to denture reline applications.

Prosthesis discomfort and a lack of skin-like quality is a source of patient dissatisfaction with facial prostheses. To engineer skin-like replacements, knowledge of the differences between facial skin properties and those for prosthetic materials is essential. This project measured six viscoelastic properties (percent laxity, stiffness, elastic deformation, creep, absorbed energy, and percent elasticity) at six facial locations with a suction device in a human adult population equally stratified for age, sex, and race. The same properties were measured for eight facial prosthetic elastomers currently available for clinical usage. The results showed that the prosthetic materials were 1.8 to 6.4 times higher in stiffness, 2 to 4 times lower in absorbed energy, and 2.75 to 9 times lower in viscous creep than facial skin (p < 0.001). Clustering analyses determined that facial skin properties fell into three groups—those associated with body of ear, cheek, and remaining locations. This provides baseline information for designing future replacements for missing facial tissues.

The objective of this study was to assess if the setting expansion, compressive strength, compressive modulus and Knoop hardness is reduced in Type III, IV and V gypsum products when excess water is added to recommended water/powder (W/P) ratios for full-arch implant master casts. Four properties were measured: linear setting expansion, compressive strength, compressive modulus, and Knoop hardness. Three dental stones were evaluated: ISO Type III, Type IV, and Type V. Water was added to recommended W/P ratios as follows: (1) 0%, the manufacturer’s recommend W/P ratio, (2) 50%, 1.5 times the manufacturer’s recommendation of water, (3) 100%, three times the manufacturer’s recommendation of water, (4) 150%, 2.5 times the manufacturer’s recommendation of water, and (5) 200%, three times the manufacturer’s recommendation of water. For all three gypsum types, 50% water additions minimally affected the setting expansion and compressive modulus (p > 0.05), but lowered compressive strength by 26% to 52% (p < 0.05). Knoop hardness was lowered by 24% and 48% for Types V and III (p < 0.05), whereas Type IV was not significantly affected (p > 0.05). With few exceptions, the physical properties for the three gypsum types reached minimum values at 100% dilution, with few changes noted at higher dilutions. Increased W/P ratios did not adequately reduce the setting expansion and adversely affected other physical properties. Of the gypsums tested, Type IV is still recommended due to its lower setting expansion for full-arch implant master casts.

Facial prosthetics are currently constructed of materials that are far from optimal; superior materials with a “skin-like” feel are required. In this study, the property changes brought about by the consecutive additions of hydrophobic- and uncoated nano-SiO₂ to polydimethylsiloxane (PDMS) are assessed, and the alterations are compared with those observed for conventional submicron SiO₂-filled materials. In sequence, 0%, 0.5%, 5%, 10%, and 15% by weight of each filler type were successively added to vinyl-terminated PDMS. Tensile, tear, Durometer hardness, translucency, and viscoelastic properties were assessed, and hardness and translucency were further measured after 3000 h of outdoor weathering. The results showed that 15% coated nano- SiO₂-filled PDMS materials given the highest tensile strength, elastic modulus, storage modulus, loss modulus, tear strength, and durometer hardness (p < 0.05), whereas 15% submicron coated SiO₂-filled materials displayed the highest failure strain and translucency parameter (p < 0.05). Only 10%- and 15%-filled submicron SiO₂ PDMS materials were altered by outdoor weathering; nevertheless, the increases were assessed to be too small to be clinically perceptible. As increased filler levels provided protection against solar radiation, heat, and moisture, only unfilled and 0.5%-filled PDMS formulations discolored from weathering. 15%-filled superhydrophobic-coated nano- SiO₂-filled PDMS was found to produce the strongest, most tear-resistant, and least translucent materials, but it also produced materials with limited stretchability and high hardness, which were regarded to be downsides for creating a “skin-like” feel.

Recent evidence suggests that nano-TiO₂ particles improve antimicrobial and physical properties when incorporated into dental prosthetic materials. However, there exists a paucity of information regarding their impact on material properties when the prosthetic materials are 3D-printed over time. The purpose of this study was to evaluate the time-dependent printability and surface property changes occurring in a 3D-printed denture base resin containing nano-titanium dioxide (TiO₂) particles. A 0.4 wt% concentration of 30 nm rutile TiO₂ nanoparticles was ultrasonically dispersed into a denture base resin. Disks were printed weekly using a Form 2 SLA printer until printing failed. Printability, surface roughness (R_a), color difference (ΔE_ab), and translucency parameters were measured across timepoints. Surface roughness was assessed via profilometry, while color and translucency were evaluated using a spectrophotometer under standardized conditions. Print failure occurred at week 8, beyond which the resin could no longer reliably produce full specimens. R_a roughness decreased from 3.83 µm to 0.48 µm, which denoted a significant time-dependent decrease (ρ = −0.733, p = 0.016). Color difference with the unmodified control declined from 26.32 to 17.13 ΔE_ab units (ρ = −0.976, p < 0.001). All printed samples exceeded the clinically acceptable thresholds for both R_a (0.2 µm) and ΔE_ab (<3.7). Although the printability of the resin–TiO2 mixture was maintained for 7 weeks, mixture homogeneity declined over time. TiO₂ additions to a denture polymer produced significant changes in surface roughness and color that were not clinically acceptable. Results from this study illustrate the time dependence required for retaining surface properties in 3D-printed dentures containing nano-TiO₂.

The incorporation of antimicrobial additives into 3D-printed denture base resins is a promising strategy for reducing denture stomatitis, but the mechanical consequences and temporal stability of such modifications remain poorly characterized. This in vitro pilot study evaluated the effects of incorporating 4% (w/w) K18—a quaternary ammonium methacryloxy silane dissolved in isobornyl acrylate (IBOA)—into three commercially available photopolymer resins printed across four platforms representing stereolithography, digital light processing, and liquid crystal display technologies. Flexural strength, flexural modulus, and flexure at break were measured at three time points: without K18, immediately after mixing, and one-week post-mixing. K18-IBOA incorporation produced significant reductions in all mechanical parameters across most resin–printer combinations. The magnitude and direction of changes were strongly dependent on printer–resin combination interactions, precluding generalization across systems. At one week, visible clumping consistent with phase separation was observed in all formulations, and one resin–printer combination exhibited catastrophic structural failure upon removal from the build platform. These findings suggest that 4% w/w K18-IBOA additions are unlikely to yield clinically acceptable denture bases without further formulation optimization, underscoring the importance of temporal stability assessment in the development of antimicrobial-modified photopolymer resins.