Aim: The mortality and morbidity of COVID-19 disease are higher in patients with comorbidities. In this study, we staged patients with chronic renal failure hospitalized in the intensive care unit (ICU) and aimed to evaluate the process of the disease according to the stage of failure. Material and Method: The medical records of 249 patients followed in Ankara City Hospital MH3 ICU were reviewed retrospectively. The patients were divided into three stages according to their estimated glomerular filtration rate (e-GFR) value (stage 1: e-GFR≥90 ml/min/1.73 m², stage-2: e-GFR: 15-89 ml/min/1.73 m², stage- 3: e-GFR≤15 ml/min/1.73 m²). Data such as age, gender, comorbidity status, length of stay in the ICU, duration of mechanical ventilation, and mortality rate of the patients were recorded. Patients who were evaluated as stage-2 were also classified into 3 stages (stage-2a: e-GFR: 60-89 ml/min/1.73 m², stage-2b: e-GFR:30-59 ml/min/1.73 m², stage-2c: e-GFR: 15-29 ml/min/1.73 m²) and evaluated with the same parameters. Results: The mean age of all patients was 71 years. It was found that the intubation rate was higher (p=0.012) and the mortality rate was higher (p=0.003) in patients evaluated as stage-3. APACHE II and SOFA scores were higher than the other groups (p=

Amaç: Bu araştırma, istenmeyen gebelikleri incelemek, risk gruplarına göre sıklığını ve nedenlerini belirlenmek amacıyla planlanmıştır. Gereçler ve Yöntem: Bu araştırma, doğum öncesi bakım almak için hastaneye başvuran 409 gönüllü evli hamile kadın üzerinde yürütülmüş olan kesitsel bir çalışmadır. Verilerin toplanmasında araştırmacılar tarafından geliştirilen anket formu kullanılmıştır. Verilerin değerlendirilmesinde yüzdelik, ortalama ve ki-kare testi kullanılmıştır. Bulgular: İstenmeyen gebelik oranı %23,2 olarak tespit edilmiştir. İstenmeyen gebelik oranı yaşla birlikte azalmaktadır. Kadınların eğitim düzeyi arttıkça istenmeyen gebelik oranı azalmakta ve bu oran üniversite mezunlarında %18,5'e düşmektedir. Sonuç: Bu araştırmada, istenmeyen gebelik oranının yüksek olması, kadınların çoğunun aile planlaması yöntemi kullanmıyor olması veya geleneksel aile planlaması yöntemleri kullanıyor olmalarından kaynaklanmaktadır. İstenmeyen gebelik oranının en yüksek olduğu risk grubunun genç kadınlar olduğu tespit edilmiştir. Geri çekme yöntemi özellikle genç kadınlarda yüksek olduğundan ve bu durum istenmeyen gebeliklere yol açabileceğinden çiftlere evlilik öncesi eğitim verilmesi gerekmektedir. Aim: This study was planned to analyse the unwanted pregnancies and to determine the frequency and causes according to risk groups. Materials and Method: This is a cross-sectional study conducted on 409 married volunteer pregnant women who applied to the hospital for prenatal care. A questionnaire prepared by the researchers was used for data collection. Percentage, mean, and chi-square test were used to evaluate the data. Results: The rate of unwanted pregnancies was found to be 23.2%. The rate of unwanted pregnancy decreases with age. The unwanted pregnancy rate decreases as the education level of the woman increases and this ratio decreases to 18.5% among university graduates. Conclusion: In this study, the high rate of unwanted pregnancies was since most of them were not using a family planning method or using traditional family planning methods. It was found that the risk group with the highest unwanted pregnancy rate was among young women. Since the rate of withdrawal method was high especially in young women and this can lead to unwanted pregnancies, it is necessary to give couples premarital education.

Objective: Every woman wants to have a healthy pregnancy and have a healthy baby, but it brings important risks. Risky pregnancies are with many different dimensions that negatively affect maternal and infant health. The aim of this study is to determine the frequency of risk factors leading to risky pregnancies which are important for public health, to reveal the reasons and to offer solutions. Methods: This is a cross – sectional study of 409 married women who applied to the hospital for prenatal care. A questionnaire prepared by the researchers was used for data collection by face-to-face interview technique. Percentage, mean, and chi-square test were used to evaluate the data. Results: Although pregnancy is a physiological process, 67.7% of the pregnant women had at least one risk factor and 27.6% had more than one risk factor. Risk factors such as having caesarean section, having four or more pregnancies, being 35 and over age, unwanted pregnancy status and having less than two years between the last two pregnancies were found to be the most common risk factors seen in pregnant women. Conclusion: Because risky pregnancies are an important public health problem and most of them are preventable; preconceptional care should be expanded to control the mother and baby before threatening their health.

Although acute kidney injury (AKI) is common among patients with coronavirus disease 2019 (COVID-19), there are only limited data on its occurrence at intensive care unit (ICU) admission. Assessing the factors associated with AKI is essential for early diagnosis and intervention. This study aims to compare the clinical and laboratory characteristics and survival outcomes of COVİD-19 patients with and without AKI at ICU admission and determine the factors associated with AKI. In this study, patients with SARS-CoV-2 infection were categorized based on the presence (AKI group) or absence (non-AKI group) of AKI. Clinical and laboratory data and outcomes were analyzed retrospectively. Of the 712 patients included in this study, 198 were assigned to the AKI group and 514 were assigned to the non-AKI group. Patients with AKI had more comorbidities and higher disease severity; higher rates of invasive mechanical ventilation, vasopressor therapy, and mortality; and longer hospital stays (p < 0.05). Our multivariate analysis identified advanced age, a high Acute Physiology and Chronic Health Evaluation II score, a high neutrophil-to-lymphocyte ratio, a low albumin level, and the presence of comorbidities as independent factors associated with AKI. In patients with COVID-19, AKI observed at ICU admission is associated with advanced age and increased disease severity. The early diagnosis and monitoring of patients may improve clinical outcomes.

Background: Renal transplant recipients are particularly vulnerable to severe viral infections due to chronic immunosuppression and a high burden of comorbidities. Coronavirus disease 2019 (COVID-19) has been associated with poor outcomes in solid organ transplant recipients, especially among those requiring intensive care unit (ICU) admission. However, data regarding prognostic factors associated with mortality in critically ill renal transplant patients with COVID-19 remain limited. Materials and Methods: This retrospective, single-center cohort study included adult renal transplant recipients admitted to the ICU with confirmed COVID-19. Demographic characteristics, comorbid conditions, and laboratory parameters obtained at ICU admission were analyzed. The primary outcome was in-hospital survival status. Secondary outcomes included the requirement for invasive mechanical ventilation, vasopressor support, renal replacement therapy, development of secondary infections, and length of ICU stay. Results: Seventeen renal transplant recipients with severe COVID-19 were included. Non-survivors required invasive mechanical ventilation more frequently than survivors (85.7% vs. 20.0%, p=0.015) and had a higher requirement for vasopressor support (p=0.004). In addition, serum interleukin-6 (IL-6) levels measured at ICU admission were significantly higher in non-survivors compared with survivors (p=0.014). Baseline demographic characteristics, comorbidities, and most conventional laboratory parameters did not differ significantly between the groups. Conclusion: In critically ill renal transplant recipients with COVID-19, the need for advanced organ support and elevated IL-6 levels at ICU admission were significantly associated with in-hospital mortality. Conventional clinical characteristics and routine laboratory markers demonstrated limited discriminative value in this high-risk population. Although the acute phase of the COVID-19 pandemic has passed, these findings provide clinically relevant insights into the vulnerability of renal transplant recipients during severe viral infections and may inform future risk assessment and preparedness strategies.