George P. Papaioannou

Dr. George P. Papaioannou


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 September 2021 in Heliyon
Verified
Journal Article
Open access
APANASTASIA PAPAIOANNOU
ANASTASIA PAPAIOANNOU
EKEva Kalantzi
Eva Kalantzi
CPChristos C. Papageorgiou
Christos C. Papageorgiou
KKKalliopi Korombili
Kalliopi Korombili
AΒAnastasia Βokou
Anastasia Βokou
GPGeorge P. Papaioannou
George P. Papaioannou
We aim to investigate whether EEG dynamics differ in adults with ASD (Autism Spectrum Disorders), ADHD (attention-deficit/hyperactivity disorder), compared with healthy subjects during the performance of an innovative cognitive task: Aristotle's valid and invalid syllogisms. We follow the Neuroanatomical differences type of criterion in assessing the results of our study in supporting or not the dual-process theory of Kahneman, 2011) (Systems I & II of thinking). We recorded EEGs from 14 scalp electrodes in 30 adults with ADHD, 30 with ASD and 24 healthy, normal subjects. The subjects were exposed in a set of innovative cognitive tasks (inducing varying cognitive loads), the Aristotle's four types of syllogism mentioned above. The multiscale entropy (MSE), a nonlinear information-theoretic measure or tool was computed to extract features that quantify the complexity of the EEG. The dynamics of the curves of the grand average of MSE values of the ADHD and ASD participants was significantly in higher levels for the majority of time scales, than the healthy subjects over a number of brain regions (electrodes locations), during the performance of both valid and invalid types of syllogism. This result is seemingly not in accordance of the broadly accepted ‘theory’ of complexity loss in ‘pathological’ subjects, but actually this is not the case as explained in the text. ADHD subjects are engaged in System II of thinking, for both Valid and Invalid syllogism, ASD and Control in System I for valid and invalid syllogism, respectively. A surprising and ‘provocative’ result of this paper, as shown in the next sections, is that the Complexity-variability of ASD and ADHD subjects, when they face Aristotle's types of syllogisms, is higher than that of the control subjects. An explanation is suggested as described in the text. Also, in the case of invalid type of Aristotelian syllogisms, the linguistic and visuo-spatial systems are both engaged ONLY in the temporal and occipital regions of the brain, respectively, of ADHD subjects. In the case of valid type, both above systems are engaged in the temporal and occipital regions of the brain, respectively, of both ASD and ADHD subjects, while in the control subjects only the visuo-spatial type is engaged (Goel et al., 2000; Knauff, 2007). Based on the results of the analysis described in this work, the differences in the EEG complexity between the three groups of participants lead to the conclusion that cortical information processing is changed in ASD and ADHD adults, therefore their level of cortical activation may be insufficient to meet the peculiar cognitive demand of Aristotle's reasoning. The present paper suggest that MSE, is a powerful and efficient nonlinear measure in detecting neural dysfunctions in adults with ASD and ADHD characteristics, when they are called on to perform in a very demanding as well as innovative set of cognitive tasks, that can be considered as a new diagnostic ‘benchmark’ in helping detecting more effectively such type of disorders. A linear measure alone, as the typical PSD, is not capable in making such a distinction. The work contributes in shedding light on the neural mechanisms of syllogism/reasoning of Aristotelian type, as well as toward understanding how humans reason logically and why ‘pathological’ subjects deviate from the norms of formal logic.

18 November 2021 in Brain Sciences
Verified
Journal Article
Open access
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APANASTASIA PAPAIOANNOU
ANASTASIA PAPAIOANNOU
EKEva Kalantzi
Eva Kalantzi
CPChristos C. Papageorgiou
Christos C. Papageorgiou
KKKalliopi Korombili
Kalliopi Korombili
ABAnastasia Bokou
Anastasia Bokou
GPGeorge P. Papaioannou
George P. Papaioannou
We aim to investigate whether EEG dynamics differ in adults with ASD (Autism Spectrum Disorders) and ADHD (attention-deficit/hyperactivity disorder) compared with healthy subjects during the performance of an innovative cognitive task, Aristotle’s valid and invalid syllogisms, and how these differences correlate with brain regions and behavioral data for each subject. We recorded EEGs from 14 scalp electrodes (channels) in 21 adults with ADHD, 21 with ASD, and 21 healthy, normal subjects. The subjects were exposed in a set of innovative cognitive tasks (inducing varying cognitive loads), Aristotle’s two types of syllogism mentioned above. A set of 39 questions were given to participants related to valid–invalid syllogisms as well as a separate set of questionnaires, in order to collect a number of demographic and behavioral data, with the aim of detecting shared information with values of a feature extracted from EEG, the multiscale entropy (MSE), in the 14 channels (‘brain regions’). MSE, a nonlinear information-theoretic measure of complexity, was computed to extract a feature that quantifies the complexity of the EEG. Behavior-Partial Least Squares Correlation, PLSC, is the method to detect the correlation between two sets of data, brain, and behavioral measures. -PLSC, a variant of PLSC, was applied to build a functional connectivity of the brain regions involved in the reasoning tasks. Graph-theoretic measures were used to quantify the complexity of the functional networks. Based on the results of the analysis described in this work, a mixed 14 × 2 × 3 ANOVA showed significant main effects of group factor and brain region* syllogism factor, as well as a significant brain region* group interaction. There are significant differences between the means of MSE (complexity) values at the 14 channels of the members of the ‘pathological’ groups of participants, i.e., between ASD and ADHD, while the difference in means of MSE between both ASD and ADHD and that of the control group is not significant. In conclusion, the valid–invalid type of syllogism generates significantly different complexity values, MSE, between ASD and ADHD. The complexity of activated brain regions of ASD participants increased significantly when switching from a valid to an invalid syllogism, indicating the need for more resources to ‘face’ the task escalating difficulty in ASD subjects. This increase is not so evident in both ADHD and control. Statistically significant differences were found also in the behavioral response of ASD and ADHD, compared with those of control subjects, based on the principal brain and behavior saliences extracted by PLSC. Specifically, two behavioral measures, the emotional state and the degree of confidence of participants in answering questions in Aristotle’s valid–invalid syllogisms, and one demographic variable, age, statistically and significantly discriminate the three groups’ ASD. The seed-PLC generated functional connectivity networks for ASD, ADHD, and control, were ‘projected’ on the regions of the Default Mode Network (DMN), the ‘reference’ connectivity, of which the structural changes were found significant in distinguishing the three groups. The contribution of this work lies in the examination of the relationship between brain activity and behavioral responses of healthy and ‘pathological’ participants in the case of cognitive reasoning of the type of Aristotle’s valid and invalid syllogisms, using PLSC, a machine learning approach combined with MSE, a nonlinear method of extracting a feature based on EEGs that captures a broad spectrum of EEGs linear and nonlinear characteristics. The results seem promising in adopting this type of reasoning, in the future, after further enhancements and experimental tests, as a supplementary instrument towards examining the differences in brain activity and behavioral responses of ASD and ADHD patients. The application of the combination of these two methods, after further elaboration and testing as new and complementary to the existing ones, may be considered as a tool of analysis in helping detecting more effectively such types of disorders.

12 September 2025 in Energies
Verified
Journal Article
Open access
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GPGeorge P. Papaioannou
George P. Papaioannou
PPPanagiotis PAPAIOANNOU
Panagiotis PAPAIOANNOU
CDChristos Dikaiakos
Christos Dikaiakos
We investigate the key factors that shape the dynamic evolution of Day-Ahead spot prices of seven European interconnected electricity markets of the Core Capacity Calculation Region, Core CCR (Austria AT, Hungary HU, Slovenia SI, Romania RO), the Southeast CCR (Bulgaria BG, Greece GR) and the Greece-Italy CCR (GRIT CCR), with emphasis on price surges and discrepancies observed in SEE CCR markets, during the period 2022–2024. The high differences in the prices of the two groups have generated political reactions from the countries that ‘suffer’ from these price discrepancies. By applying Machine Learning (ML) approaches, as Markov Blanket (MB) and Local, causal structures learning (LCSL), we are able of ‘revealing’ the entire path of volatility spillover of both spot price and the Cross-Border Transfer Availabilities (CBTA) between the countries involved, from north to south, thus uncovering i.e., ‘lifting the blanket’, to discover the ‘true’ structure’ of the path of causalities, responsible for the price disparity. The above methods are supported by the ‘mainstream’ approach of computing the correlation of the spot price and CBTA’s volatility curves of all markets, to detect volatility spillover effects across markets. The main findings of this hybrid approach are (a) the volatility of some Core CCRs (AT, HU, RO) markets’ spot price and CBTAs with neighboring countries, ‘uncovered’ to be pivotal, operating as a ‘transmitter’ of volatility ‘disturbances’, over its entire connection and causal path from Core CCR to SEE CCR markets, partially contributing to their price surge, (b) reduced available capacity for cross-border trading of some Core and SEE CCRs (they have not satisfied the minimum 70% requirement margin available for cross-zonal trade, MACZT), combined with local weather and geopolitical conditions, could have exacerbated the impact of the Flow-based Market coupling method (FBMC) used in the Core CCRs, on the prices’ surge of SEE CCR’s countries, e.g., via induced non-intuitive flows. This phenomenon questions the efficiency and reliability of the European Target’s model (TM) in securing ‘homogeneous’ power prices across all interconnected markets, core and peripheral.

12 July 2024 in Sustainability
Verified
Journal Article
Open access
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CKChristos D. Kaskouras
Christos D. Kaskouras
KKKonstantinos Krommydas
Konstantinos Krommydas
IBIoannis Baltas
Ioannis Baltas
GPGeorge P. Papaioannou
George P. Papaioannou
GPGeorgios Papayiannis
Georgios Papayiannis
AYAthanasios N. Yannacopoulos
Athanasios N. Yannacopoulos
Increasing the generation of electric power from renewable energy sources (RESs) creates important challenges to transmission system operators (TSOs) for balancing the power system. To address these challenges, adequate system flexibility is required. In this context, TSOs carry out flexibility assessment studies to evaluate the flexibility level of the power system and ensure that a stable operation of the transmission system under high RESs integration can be achieved. These studies take into consideration numerous scenarios incorporating different assumptions for temperature, RESs penetration, load growth, and hydraulic conditions. Until now, flexibility studies usually solve the standard unit commitment problem and evaluate if the flexibility level is adequate. Although this approach provides quite accurate results, the computational requirements are significant, resulting in limiting the scenarios chosen for examination. In this paper, deep learning approaches are examined, and more precisely, an integrated system of two recurrent neural networks with long short-term memory cells is designed to carry out the flexibility assessment task, aiming at the reduction in the computational time required by the optimization process. The output of this neural network system is then used to calculate the probability of flexibility shortages. The proposed method is evaluated based on data from the Hellenic transmission system, providing quite promising results in (a) accurately calculating the probability of insufficient flexibility and (b) achieving a significant decrease in computational time. This novel approach could notably facilitate TSOs since more scenarios can be included, exploiting the computational efficiency of the method. In this way, a more complete evaluation of the flexibility level of the power system can be achieved and thus help to ensure the stable and reliable operation of the transmission system.

4 March 2024 in Brain Sciences
Verified
Journal Article
Open access
PDF file
AKAnna Karavia
Anna Karavia
APANASTASIA PAPAIOANNOU
ANASTASIA PAPAIOANNOU
IMIoannis Michopoulos
Ioannis Michopoulos
PPPanos Papageorgiou
Panos Papageorgiou
GPGeorge P. Papaioannou
George P. Papaioannou
CPCharalabos C. Papageorgiou
Charalabos C. Papageorgiou
Anorexia nervosa is associated with impaired cognitive flexibility and central coherence, i.e., the ability to provide an overview of complex information. Therefore, the aim of the present study was to evaluate EEG features elicited from patients with anorexia nervosa and healthy controls during mental tasks (valid and invalid Aristotelian syllogisms and paradoxes). Particularly, we examined the combination of the most significant syllogisms with selected features (relative power of the time–frequency domain and wavelet-estimated EEG-specific waves, Higuchi fractal dimension (HFD), and information-oriented approximate entropy (AppEn)). We found that alpha, beta, gamma, theta waves, and AppEn are the most suitable measures, which, when combined with specific syllogisms, form a powerful tool for efficiently classifying healthy subjects and patients with AN. We assessed the performance of triadic combinations of “feature–classifier–syllogism” via machine learning techniques in correctly classifying new subjects in these two groups. The following triads attain the best classifications: (a) “AppEn-invalid-ensemble BT classifier” (accuracy 83.3%), (b) “Higuchi FD-valid-linear discriminant” (accuracy 75%), (c) “alpha amplitude-valid-SVM” (accuracy 83.3%), (d) “alpha RP-paradox-ensemble BT” (accuracy 85%), (e) “beta RP-valid-ensemble” (accuracy 85%), (f) “gamma RP-valid-SVM” (accuracy 85%), and (g) “theta RP-valid-KNN” (accuracy 80%). Our findings suggest that anorexia nervosa has a specific information-processing style across reasoning tasks in the brain as measured via EEG activity. Our findings also contribute to further supporting the view that entropy-oriented, i.e., information-based features (the AppEn measure used in this study) are promising diagnostic tools (biomarkers) in clinical applications related to medical classification problems. Furthermore, the main EEG-specific frequency waves are extremely enhanced and become powerful classification tools when combined with Aristotle’s syllogisms.

22 July 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
GPGeorge P. Papaioannou
George P. Papaioannou
PPPanagiotis PAPAIOANNOU
Panagiotis PAPAIOANNOU
CDChristos Dikaiakos
Christos Dikaiakos
We investigate the key factors that shape the dynamic evolution of Day-Ahead spot prices of seven European interconnected electricity markets of the Core Capacity Calculation Region, Core CCR (Austria AT, Hungary HU, Slovenia SI, Romania RO), the Southeast CCR (Bulgaria BG, Greece GR) and the Greece-Italy CCR , GRITR (Italy), with emphasis on price surges and discrepancies observed in SEE CCR markets, during the period 2022-2024. The high differences in the prices of the two groups, has generated political reactions from the countries that ‘suffer’ from these price discrepancies, as shown by the intense reactions of the governments of the affected countries and other institutions, as the sending of letters of Prime Ministers European Commission President). By applying Machine Learning (ML) approaches, as Markov Blanket (MB) and Local, causal structures learning (LCSL), we are able of ‘revealing’ the entire path of volatility spillover of spot price as well as the Cross-Border Transfer Availabilities (CBTA) between the countries involved, from north to south, thus uncovering i.e. ‘lifting the blanket’, to discover the ‘true’ structure’ of the path of causalities, responsible for the price disparity. The above methods are supported by the ‘mainstream’ approach of computing the correlation of the spot price and CBTA’s volatility curves of all markets, to detect volatility spillover effects across markets. The main findings of this hybrid approach are: a) the volatility of Austrian market’s spot price and its CBTAs with DE, CZ, and SI, ‘uncovered’ to be a pivotal market, behaving as a ‘transmitter’ of spot price and cross-border activity volatility, over its entire connection path with SEE CCR markets, which finally ‘receive’ the volatility disturbances, causing their price surge, b) the combination of weather and geopolitical factors with the limited interconnectivity of SEE markets, seem to have exacerbated the impact of the Flow-based Market coupling method (FBMC) used in the Core CCRs, on the prices of SEE CCR’s countries that rely on the Net Transfer Capacity -NTC- mechanism, by inducing non-intuitive flows, thus challenging the reliability of European Target’s model (based on FBMC) in protecting SEE markets from ‘unexpected-unfair-irrational’ price surge.