Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant, antimicrobial, anti‐inflammatory, mitoprotective, and neuroprotective activity. Research on their broad‐scope bioactivity experienced a renaissance in the early 2000s, and further accelerated after COVID‐19, including research on their antimicrobial properties. Summarizing selected research achievements on the antimicrobial activity of the main Citrus flavonoids, this study aims to provide a unified picture on the antimicrobial properties of these valued compounds that will hopefully assist in the development of flavonoid‐based antimicrobials, including antibacterial treatments suitable for clinical use minimizing antimicrobial resistance.
Citrus IntegroPectin is a family of bioconjugates sourced from different citrus fruits first isolated in 2019 via hydrodynamic cavitation of industrial citrus processing biowaste conducted in water only. Having a low methoxyl homogalacturonan backbone, these new pectins are enriched in citrus flavonoids, terpenes, and RG‐I rhamnogalacturonan regions. Investigating lemon, grapefruit, orange, red orange, and mandarin IntegroPectin in numerous in vitro and in vivo studies unveiled their multitarget biological activity, including antioxidant, anti‐inflammatory, cardioprotective, anti‐apoptotic, immunomodulatory, neuroprotective, mitoprotective, antimicrobial, and anticancer properties. This review summarizes research achievements in the first five years following the discovery of IntegroPectin. A critical perspective toward production and practical uptake of this new family of bioconjugates for the treatment and prevention of numerous ailments concludes this account.
Enhancement of alkaline water electrolysis requires the development of anion exchange membranes (AEMs) combining high permselectivity with a low resistance to ion transport and stability during prolonged contact with a concentrated alkaline solution. We now report that CytroCell@PIL, a mixed matrix membrane obtained by a synergic combination of CytroCell micronized citrus cellulose mixed at a 1 wt% load with a polymerizable ionic liquid (triethyl(4‐vinylbenzyl)phosphonium tetrafluoroborate), shows vastly enhanced chemical and physical stability along with promising ionic conductivity. These findings establish the proof of concept toward the development of technical and economically viable large‐area AEMs using polymeric membranes chemically and physically stabilized by CytroCell sustainably sourced via cavitation of industrial citrus processing waste conducted in water only.
Little scholarly research has been published on the cosmetic uses of tannins. This study identifies the emerging uses of tannin as cosmeceutical ingredient in skin and hair care products. A green chemistry, health, and economic perspective is offered on future developments concerning the use of tannins in cosmetic products massively employed such as hair dyes and hair relaxers. Besides filling a gap in the literature, the study will hopefully accelerate the uptake of tannins as cosmeceutical ingredients in cosmetic products widely used worldwide such as hair dyes and hair relaxers, eventually replacing harmful chemicals with a class of natural products imparted with broad‐scope health‐beneficial properties.