Alzheimer’s disease (AD) is a progressive disease that causes problems of cognitive and memory functions decline. Patients with AD usually lose their ability to manage their daily life. Exploring the progression of the brain from normal controls (NC) to AD is an essential part of human research. Although connection changes have been found in the progression, the connection mechanism that drives these changes remains incompletely understood. The purpose of this study is to explore the connection changes in brain networks in the process from NC to AD, and uncovers the underlying connection mechanism that shapes the topologies of AD brain networks. In particular, we propose a mutual information brain network model (MINM) from the perspective of graph theory to achieve our aim. MINM concerns the question of estimating the connection probability between two cortical regions with the consideration of both the mutual information of their observed network topologies and their Euclidean distance in anatomical space. In addition, MINM considers establishing and deleting connections, simultaneously, during the networks modeling from the stage of NC to AD. Experiments show that MINM is sufficient to capture an impressive range of topological properties of real brain networks such as characteristic path length, network efficiency, and transitivity, and it also provides an excellent fit to the real brain networks in degree distribution compared to experiential models. Thus, we anticipate that MINM may explain the connection mechanism for the formation of the brain network organization in AD patients.

Road capacity, traffic safety, and energy efficiency can be extremely improved by forming platoons with a small intra-vehicle spacing. Automated controllers obtain vehicle speed, acceleration, and position through vehicular ad hoc networks (VANETs), which allows the performance of platoon communication to make a significant impact on the stability of the platoon. To the best of our knowledge, there is not much research relating to packet delay and packet dropping rate of platoon communication based on the IEEE 802.11p broadcasting. In this paper, we introduce platoon structure model, vehicle control model, and communication model for a single platoon scenario. By utilizing Markov process and M/G/1/K queuing theory, we put forward an analytical model to assess the property of intra-vehicle communication. The analytical model is validated by simulations and the influence of communication parameters on intra-vehicle communication performance are discussed. In addition, the experimental results demonstrate that the IEEE 802.11p-based intra-vehicle communication guarantee the stability of platoon.