Aree Thayananuphat

Dr. Aree Thayananuphat


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 July 2016 in Veterinary Ophthalmology
Verified
Journal Article
Closed access
PDF file
NSNatthanet Sritrakoon
Natthanet Sritrakoon
PMPhudit Maneesaay
Phudit Maneesaay
WKWinyu Karntip
Winyu Karntip
ATAree Thayananuphat
Aree Thayananuphat

1 January 2021 in Open Veterinary Journal
Verified
Journal Article
Open access
NSNatthanet Sritrakoon
Natthanet Sritrakoon
KSKaset Sutasha
Kaset Sutasha
CKChaiyan Kasorndorkbua
Chaiyan Kasorndorkbua
WKWinyu Karntip
Winyu Karntip
NJNoppasin Jindawattana
Noppasin Jindawattana
ATAree Thayananuphat
Aree Thayananuphat
Cataract is a common disease in the lenses of birds. Cataract surgery is the recommended treatment for birds with visual impairment. Nevertheless, reports of the results of cataract surgery in birds are limited. An unknown-aged male black kite (Milvus migrans) was presented to Kasetsart University Veterinary Teaching Hospital to evaluate and treat bilateral ocular cloudiness. Bilateral hypermature cataracts were diagnosed. A-scan biometry was carried out to calculate the intraocular lens’ (IOL) diopter power. Bilateral cataract extraction by lens aspiration with +17.5 diopter foldable IOL implantation was successfully completed. Two months after surgery, the black kite navigated well and could fly and catch his food. Retinoscopy at 4 months postoperative revealed −0.5 diopters OD, whereas OS could not be assessed due to a poor reflection. Follow-up at 3 years after surgery, the black kite’s vision remained favorable. Phacoemulsification and IOL implantation were successful in this black kite because the black kite’s vision was noticeably improved, and the black kite was able to navigate well. To the authors’ knowledge, this is the first report of bilateral cataract surgery with IOL implantation using a calculated dioptric power (+17.5 D) IOL in a black kite.

30 June 2021 in Veterinary World
Verified
Journal Article
Open access
MSMetita Sussadee
Metita Sussadee
RRRucksak Rucksaken
Rucksak Rucksaken
PHPhattara-Orn Havanapan
Phattara-Orn Havanapan
OROnrapak Reamtong
Onrapak Reamtong
ATAree Thayananuphat
Aree Thayananuphat
Background and Aim: Keratoconjunctivitis sicca (KCS) is a chronic inflammatory ocular disease that occurs in many dog breeds worldwide. This study aimed to investigate the tear protein pattern of healthy dogs, KCS dogs, and KCS dogs after treatment with cyclosporine A (CsA). Materials and Methods: Twenty-eight dogs of any breed were enrolled in the study. The subjects were divided into three groups: Healthy, KCS, and CsA-treated dogs. Tear samples were collected using Schirmer strips. Tear proteins extracted from the strips were analyzed using two-dimensional electrophoresis. For the first dimension, total protein from tears was separated by isoelectric focusing. The second dimension was performed using 12.5% sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The gel images were analyzed and the protein spots of differential expression were manually cut for protein annotation using mass spectrometry. Results: In total, 12 protein spots were excised and subjected to protein identification. Associated with KCS, six protein spots were a downregulated protein, namely, lysozyme. The other six protein spots were upregulated in KCS dogs, consisting of heat shock protein beta-1, protein S100-A12, and keratin type II cytoskeletal 1 and 5. After treatment with CsA for 45 days, the lysozyme protein was still decreasing and the inflammation protein (S100-A12) was not identified. Conclusion: Inflammatory tear proteins and proteins involved in cellular stress were present in KCS dogs and appeared to be reduced in medicated eyes. Treatment with topical CsA in the short term may not improve the activity of antibacterial proteins. Changes in the expression patterns of these four proteins might be useful for disease severity and progression assessment, as well as for exploring a novel method for dry eye management in dogs.

21 March 2021 in Open Veterinary Journal
Verified
Journal Article
Open access
PDF file
NSNatthanet Sritrakoon
Natthanet Sritrakoon
WKWinyu Karntip
Winyu Karntip
SNSirirat Niyom
Sirirat Niyom
SKSusadee Khemton
Susadee Khemton
PPPanuwat Pakpiboon
Panuwat Pakpiboon
ATAree Thayananuphat
Aree Thayananuphat
Background: Cataracts are the major cause of visual impairment in animals which can be curable by surgical treatment. Phacoemulsification is the standard technique for cataract treatment that is applied to almost all species with a high success rate. Case Description: A 2-year-old intact female orangutan (Pongo pygmaeus) was presented for the study having bilateral opacity of the lenses, for 2 weeks. Ophthalmic examination revealed mature cataract OU. Ocular biometry measurements using A-scan ultrasonography for appropriate intraocular lens (IOL) refractive power calculation were carried out. Electroretinography was applied to ensure retinal function is intact. The orangutan underwent phacoemulsification OU and +24 diopter IOL implantation OS to restore vision. IOL implantation was not carried out OD because of a posterior capsular tear. Retinoscopy after 3 weeks postoperatively revealed +2.0 diopters OS. The outcome of the cataract surgery was successful during 3 years follow-up. The orangutan lived with other orangutans and was alert with normal behavior such as catching food, climbing trees, and swinging hand over hand from one branch to another. Conclusion: Cataract surgery with phacoemulsification OU and adjusted IOL implantation OD was successful with few complications in this orangutan. Vision was restored with normal behavior, even though an adjusted IOL was inserted in only one eye.

3 October 2025 in Animals
Verified
Journal Article
Open access
PDF file
NSNatthanet Sritrakoon
Natthanet Sritrakoon
KJKanyarat Jitsophakul
Kanyarat Jitsophakul
LALadawan Areevijittrakul
Ladawan Areevijittrakul
ATAree Thayananuphat
Aree Thayananuphat
Cataracts cause vision loss in rabbits, often either spontaneously or as secondary to uveitis. This study considers the ophthalmic presentation, treatment, and outcome of phacoemulsification in seven pet rabbits: six presenting with lens cloudiness and one presenting with a white mass in the iris. Ophthalmic examinations revealed cataracts. The treatment plan was phacoemulsification. Encephalitozoon cuniculi was identified via an enzyme-linked immunosorbent assay technique performed on all rabbits. Ocular ultrasonography was performed to rule out retinal detachment. Phacoemulsification using the one-handed technique without intraocular lens implantation was performed in 8 of the eyes of the 7 rabbits. After surgery, the corneal wounds healed within 2 weeks. All rabbits were comfortable with opening their eyes and had a positive dazzle reflex and a clear visual axis, with no other severe complications (such as retinal detachment, intraocular hemorrhaging, or uncontrolled glaucoma) throughout the post-operative period. Postoperative complications consisted of corneal edema around the surgical wound (2 eyes; 25%); partial anterior synechiae (1 eye; 12.5%); partial posterior synechiae (5 eyes; 3 eyes before surgery and 2 eyes after surgery; 25%); posterior capsular opacities (3 eyes; 37.5%); and lens fiber overgrowths (2 eyes; 25%). In conclusion, successful phacoemulsification was achieved in the seven pet rabbits.

1 January 2023 in Open Veterinary Journal
Verified
Journal Article
Open access
NSNatthanet Sritrakoon
Natthanet Sritrakoon
WWWinutpuksinee Wibulchan
Winutpuksinee Wibulchan
WKWinyu Karntip
Winyu Karntip
TSTheerapol Sirinarumitr
Theerapol Sirinarumitr
ATAree Thayananuphat
Aree Thayananuphat
Background: Multilobular tumor of bone or multilobular osteochondrosarcoma is a tumor of flat bone in the skull. The treatment of choice for a multilobular tumor of bone is local aggressive surgical excision. Case Description: A female Cocker Spaniel dog aged 11 years presented with a history of globe displacement of the right eye for 3 months. Ophthalmic examination revealed exophthalmos, third eyelid protrusion and slightly increased intraocular pressure OD. Computed tomography (CT) revealed a mass effect in the right retrobulbar, maxilla, zygomatic, and temporal areas. Right zygomatic and temporal bone lysis was observed. Physical examination, hematology, and blood chemistry results were within normal limits. Exenteration with zygomatic arch removal was performed. During surgery, a firm 2-lobed mass (4.8x3.7 cm and 1.6x1.4 cm) adhered to the mandible was found in the retrobulbar area OD. Histopathological findings revealed a multilobular tumor of bone. CT imaging was performed for the remaining tumor and an extended part of the right retrobulbar mass was found. Hypofractioned radiotherapy with 6 fractions of 6 Gy was performed on days 0, 7, 14, 21, 28, and 35. At 1 month and 4 months follow-up inspections, the mass gradually reduced in size. At 8 months and 11 months after radiotherapy, the mass was unremarkable. The dog was alert during all follow-up periods to 1 year and 8 months after hypofractioned radiotherapy combined with exenteration and partial orbitectomy. Conclusions: Hypofractioned radiotherapy combined with exenteration and partial orbitectomy extended the patient’s survival and decreased the size of the remaining tumor for the management of orbital multilobular tumor of bone in this dog for at least 1 year and 8 months.