Ruben Rodrigo Lozano-Salazar

Dr. Ruben Rodrigo Lozano-Salazar

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 May 2025 in Archives of Medical Research
Verified
Journal Article
Closed access
Nahum Mendez-SanchezNahum Mendez-Sanchez
Nahum Mendez-Sanchez
MRMariana M Ramírez-Mejía
Mariana M Ramírez-Mejía
MZMing-Hua Zheng
Ming-Hua Zheng
CCCarlos Cortez-Hernández
Carlos Cortez-Hernández
ETElianee M Tovar-Bojorquez
Elianee M Tovar-Bojorquez
HRHeriberto Rodríguez-Hernández
Heriberto Rodríguez-Hernández

1 September 2021 in Annals of Hepatology
Verified
Journal Article
Open access
RNRodrigo Gaspar Díaz Novelo
Rodrigo Gaspar Díaz Novelo
RLRuben Rodrigo Lozano-Salazar
Ruben Rodrigo Lozano-Salazar
NDNina Méndez Domínguez
Nina Méndez Domínguez

8 October 2026 in Livers
Verified
Journal Article
Open access
PDF file
OMOsvaldo Huchim Méndez
Osvaldo Huchim Méndez
RLRuben Rodrigo Lozano-Salazar
Ruben Rodrigo Lozano-Salazar
CCCarlos Chan-Nuñez Chan-Nuñez
Carlos Chan-Nuñez Chan-Nuñez
Edgar Villarreal-JimenezEdgar Villarreal-Jimenez
Edgar Villarreal-Jimenez
ANAdrian Perez Navarrete
Adrian Perez Navarrete
Nina Mendez-DominguezNina Mendez-Dominguez
Nina Mendez-Dominguez
Background/Objectives: Mirizzi syndrome (MS) alters biliary anatomy, complicating diagnosis and treatment. We characterized diagnostic pathways in reported cases and compared Csendes type I with types II–V. Methods: PubMed and Scopus were searched through 1 July 2026, supplemented by citation searching. Reports of five or fewer patients were eligible. Patient-level diagnostic, treatment, and outcome data were summarized; groups were compared using Fisher’s exact and Mann–Whitney U tests. Results: We included 133 publications reporting 141 patients. MS was diagnosed preoperatively in 115/138 patients (83.3%). Recognition was more frequent in type I than types II–V (92.5% vs. 76.7%; p = 0.037) and among patients with conventional imaging (94.0% vs. 76.0%; p = 0.014). ERCP use and the number of modalities did not differ by diagnostic status. Compared with type I, types II–V more frequently required bile-duct exploration (37.1% vs. 17.0%), underwent open surgery (43.5% vs. 24.5%), and developed bile leak (24.1% vs. 8.5%) or treatment-related bile-duct injury (24.1% vs. 4.3%). Conclusions: Preoperative recognition was common but less frequent in fistulizing forms. Anatomical classification and conventional imaging may assist operative planning, whereas accumulating modalities showed no diagnostic advantage.

1 January 2022 in Cirujano General
Verified
Journal Article
Open access
PDF file
MOMiguel A Osorio-Navarrete
Miguel A Osorio-Navarrete
ERErik Ruiz-Casanova
Erik Ruiz-Casanova
RURodrigo Urbina-Chapoy
Rodrigo Urbina-Chapoy
RLRuben Rodrigo Lozano-Salazar
Ruben Rodrigo Lozano-Salazar
RESUMEN La endoprótesis es una modalidad terapéutica bien aceptada para numerosas enfermedades de la vía biliar. La migración distal es una complicación rara que puede llevar a complicaciones graves. En 1996 se reportó la primera perforación del colon izquierdo secundario a una prótesis biliar plástica, y desde entonces se han reportado cuarenta casos más. Presentamos el caso de una paciente que desarrolló un abdomen agudo trece meses después de la colocación de una endoprótesis. Durante la cirugía se localizó la prótesis a través de un divertículo en el colon sigmoides. Se realizó un cierre primario, con un desenlace clínico adecuado, conveniente evolución y egreso por mejoría, así como un seguimiento externo apropiado.

1 January 2026 in Case Reports in Surgery
Verified
Journal Article
Open access
PDF file
RLRuben Rodrigo Lozano-Salazar
Ruben Rodrigo Lozano-Salazar
XRXavier Rios-Covian-Molina
Xavier Rios-Covian-Molina
ARAndrea Rochel-Perez
Andrea Rochel-Perez
OMOsvaldo Huchim Méndez
Osvaldo Huchim Méndez
OFOmar Bermudez Ferro
Omar Bermudez Ferro
Nina Mendez-DominguezNina Mendez-Dominguez
Nina Mendez-Dominguez
Background: Fibrolamellar hepatocellular carcinoma (FL‐HCC) is a rare variant of hepatocellular carcinoma (HCC) that typically arises in non‐cirrhotic livers and affects younger individuals compared with conventional HCC. Because patients usually have preserved hepatic function, surgical resection may be feasible even in the presence of large tumors. However, diagnostic uncertainty and concerns regarding extrahepatic disease may limit initial surgical decision‐making. Case Presentation: We report the case of a 48‐year‐old male patient who presented with epigastric discomfort, weight loss, and a palpable abdominal mass. Contrast‐enhanced imaging demonstrated a large hepatic lesion involving segments II, III, and IV, with additional pulmonary and adrenal findings initially raising concern for metastatic disease. The patient had previously been declined surgical treatment at another institution. Further multidisciplinary evaluation, imaging reassessment, and histological confirmation by percutaneous biopsy supported the diagnosis of FL‐HCC without confirmed metastatic disease. An open anatomical left hepatectomy was performed. Histopathology confirmed FL‐HCC with negative surgical margins and no lymph node metastases. Follow‐up 36 months after surgery demonstrated no evidence of recurrence. Conclusion: This case highlights the importance of comprehensive staging and multidisciplinary reassessment in patients with suspected FL‐HCC. Even when surgery has initially been declined, careful evaluation may identify candidates for potentially curative hepatic resection. Long‐term surveillance remains essential due to the risk of recurrence following resection. Additionally, this report illustrates that FL‐HCC can occur outside the typical age range, emphasizing the need to consider this diagnosis in compatible clinical and radiologic contexts.

2 June 2026 in Livers
Verified
Journal Article
Open access
PDF file
OMOsvaldo Huchim Méndez
Osvaldo Huchim Méndez
RLRuben Rodrigo Lozano-Salazar
Ruben Rodrigo Lozano-Salazar
AMAlejandro Daniel Munive-Ramirez
Alejandro Daniel Munive-Ramirez
JMJorge E Mendicuti-Carillo
Jorge E Mendicuti-Carillo
ERErick Rochel
Erick Rochel
Nina Mendez-DominguezNina Mendez-Dominguez
Nina Mendez-Dominguez
Porcelain gallbladder (PGB) has historically been considered a premalignant condition, although recent evidence questions the strength of its association with gallbladder carcinoma. Objective: To describe the occurrence and characteristics of malignancy in patients with porcelain gallbladder, as well as clinical, imaging, and surgical characteristics reported in clinal cases. Methods: A systematic review of case reports and case series (≤5 patients) was conducted following PRISMA 2020 guidelines. PubMed/MEDLINE, ScienceDirect, and Redalyc from database inception through March 2026. Individual patient data were extracted including demographic characteristics, imaging findings, calcification pattern, surgical management, histopathology, and outcomes. Descriptive statistics were performed. Results: Fifty-four individual cases of porcelain gallbladder were identified. Patients were predominantly female (70.4%), with ages ranging from 6 to 98 years. Complete calcification was reported in 85.2% of cases. Histopathological confirmation was available in 45 cases (83.3%). Thirteen patients had gallbladder carcinoma associated with porcelain gallbladder, corresponding to 28.9% of those with pathological examinations. Incomplete calcification showed higher frequency of malignancy compared with complete calcification. Mortality was reported in three patients (5.6%), all with malignant disease. Conclusions: The proportion of malignancy observed in published case reports reflects a selected dataset and should not be interpreted as an estimate of population risk. These findings provide descriptive insights into clinical presentations and management patterns, supporting hypothesis generation rather than risk estimation.