Glutamate amidation, a secondary modification of the peptidoglycan, was first identified in Staphylococcus aureus . It is catalyzed by the protein products of the murT and gatD genes, which are conserved and colocalized in the genomes of most sequenced Gram-positive bacterial species. The MurT-GatD complex is required for cell viability, full resistance to β-lactam antibiotics, and resistance to human lysozyme and is recognized as an attractive target for new antimicrobials.
1 July 2026 in Environmental Science and Pollution Research
This study examined quality of life and deep learning among 109 veterinary medicine students across three cohorts (2021–2023) in an integrated modular curriculum in Portugal. Quality of life was measured three times per academic year using the WHOQOL-BREF, whereas deep learning was assessed twice yearly via assessment tests. The results revealed consistently low scores in the psychological domain of the quality-of-life assessment and a noticeable decline in both quality of life and assessment tests during the second year. These findings highlight the need to monitor student well-being and adapt teaching strategies to sustain motivation and academic success.