Background/Objectives: Isolated cleft lips and/or palates often require orthognathic treatment. Traditional planning based on 2D images and plaster models limits precision; therefore, virtual surgical planning (VSP) and Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) technologies are increasingly being used. The aim of this scoping review was to analyze the techniques, outcomes, and gaps in research on VSP in orthognathics for patients with isolated (non-syndromic) clefts. Methods: Searches were conducted in July 2025 in seven databases (including PubMed, Scopus, and Cochrane) without language restrictions, in accordance with the PRISMA guidelines for scoping reviews. Of the 2836 records, 36 publications were eligible after deduplication and full-text screening, and their Level of Evidence (LoE) was assessed using the Oxford CEBM scale. A risk of bias assessment was also conducted according to JBI tools. Results: The identified studies primarily comprised LoE III and IV; there were no systematic reviews or randomized controlled trials (LoE I). Descriptions of bimaxillary procedures and LeFort I osteotomies dominated. The most commonly used software was ProPlan CMF, Dolphin 3D, and Rhinoceros, although other tools have emerged in recent years. The available studies suggest that VSP increases translational and rotational accuracy and facilitates individualized treatment, and bimaxillary procedures bring better functional and aesthetic outcomes in patients with severe maxillary hypoplasia. Conclusions: Despite the growing interest in VSP in orthognathics, the scientific evidence is limited and mostly of lower quality. Well-designed prospective studies are needed to assess the long-term stability, quality of life, and cost-effectiveness of modern technologies.

Background/Objectives: Nasal septal deviation (NSD) is a common anatomical condition that may influence nasal airflow and has been proposed as a potential factor associated with craniofacial growth and morphology. However, available studies use heterogeneous classifications and measurement methods, including the Mladina classification, angular parameters, volumetric assessment, CT, CBCT, and cephalometric analyses. This scoping review aimed to map and synthesize the available evidence on the relationship between NSD classifications, including the Mladina system, and craniofacial morphological correlates. Methods: This scoping review was conducted according to Joanna Briggs Institute methodology for scoping reviews and reported in accordance with the PRISMA-ScR checklist. The protocol was prospectively registered in the Open Science Framework. A broad literature search was performed in PubMed, Embase, Cochrane Library, BASE, and Google Scholar, without restrictions on publication date or language. Eligible studies included clinical or academic investigations assessing NSD using a defined classification or quantitative parameters and relating it to craniofacial, maxillary, mandibular, dentofacial, or asymmetry-related outcomes. Results: From 715 identified records, 387 remained after deduplication, and 6 studies met the inclusion criteria. The included studies varied substantially in sample size, imaging modality, NSD assessment method, and outcome domains. The most consistent findings suggested associations between NSD and localized or transverse nasomaxillary changes, particularly involving the palate, maxilla, nasal floor, and dentoalveolar region. Evidence regarding global facial asymmetry, basic maxillomandibular dimensions, and malocclusion was limited and inconsistent. Studies using the Mladina classification did not provide uniform conclusions across outcome domains. Conclusions: Current evidence does not support NSD as a uniform marker of global craniofacial morphology abnormalities. NSD appears more plausibly associated with selected local and transverse nasomaxillary features than with overall facial asymmetry. Future studies should combine standardized NSD classifications, especially the Mladina system, with precise three-dimensional craniofacial assessment in homogeneous populations.