Background: In recent years, hyaluronic acid filler for the restoration and increase in buttock volume has been a procedure that has seen increasing success, both thanks to the considerable increase in patient demand and thanks to the improvement of implant techniques and device manufacturing technologies. Aims: The primary objective of this pilot study is to demonstrate the validity of an innovative filler inoculation technique in the upper quadrants of the buttocks and in the supra- and subfascial area in order to optically restore the appearance of a pleasant lumbar lordosis and to lift the upper quadrants with reduction in the infragluteal fold. The secondary objective is to evaluate the safety and efficacy of Sofiderm SubSkin^® (Techderm Biological Products Co., Ltd., Hangzhou, China), a highly versatile hyaluronic acid filler, formulated with a rheology suitable for use on the face and body. Patients/Methods: Five female subjects (50–63 years) were subjected to gluteal fillers in the supra- and subfascial areas; the correct positioning of the filler was investigated by means of a 20 Mhz ultrasound probe. Results: All patients obtained a significant improvement in the projection of the upper part of the buttocks. The implantation technique and the optimal rheological properties of the device brought about a natural and well-defined increase in volume, with a projection of the upper part of the buttocks and a consequent lifting of the lower parts and reduction in the length of the infragluteal fold. Conclusions: This study confirmed the efficacy and safety of the cross-linked hyaluronic acid Sofiderm Derm SubSkin^® in increasing the projection of the upper part of the buttocks, using an innovative mixed implantation technique, in a sample of selected patients.

Background: Lip aging is a heterogeneous and visually complex process, yet a standardized morphological classification applicable to clinical practice is still lacking. Current approaches mainly focus on volumetric loss or perioral rhytids, while the geometric features of the lips, including borders, projection, and eversion, remain poorly codified. Methods: Fifty anonymized lip images acquired under standardized conditions using digital facial imaging were independently evaluated by five physicians experienced in esthetic medicine. Images were classified according to three predefined morphotypes representing distinct patterns of lip aging. Inter-rater reliability was assessed using Fleiss’s kappa statistic. Results: Three recurrent morphotypes were consistently identified: devolumized lips, central lips, and chapped lips. Overall, 87% of images were assigned to one of the three morphotypes by at least four of five evaluators, while 13% were classified as undefined due to mixed features. Inter-rater agreement was substantial (κ = 0.89; 95% CI 0.79–0.99), confirming high reproducibility of the proposed classification. Conclusions: This study proposes a simple and reproducible image-based morphotypic classification of lip aging that captures recurrent visual patterns within this cohort. The framework may facilitate standardized clinical communication, support personalized rejuvenation strategies, and provide a foundation for future quantitative imaging studies and AI-based phenotype recognition in esthetic and reconstructive practice.