Mariana Lidia Cevei

Dr. Mariana Lidia Cevei


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 October 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
Osser BrigitteOsser Brigitte
Osser Brigitte
TCToth - Csongor
Toth - Csongor
Carmen Delia Nistor CseppentoCarmen Delia Nistor Cseppento
Carmen Delia Nistor Cseppento
Iosif IliaIosif Ilia
Iosif Ilia
Gyongyi OsserGyongyi Osser
Gyongyi Osser
LRLaura Ioana Rădoi
Laura Ioana Rădoi
Background: Scoliosis, a three-dimensional spinal deformity, can impair posture, function, and quality of life. Conservative approaches such as structured physical therapy are widely used, but evidence from long-term, real-world settings remains limited. In this study, “structured” refers to a standardized, supervised program delivered three times per week, incorporating postural correction, Klapp-based positioning, core strengthening, flexibility training, and progressive intensity adjustments rather than ad hoc or unsupervised exercise. Methods: In this 12-month longitudinal study, 240 patients aged 15–19 years with idiopathic scoliosis (Cobb angle 15–25°) were enrolled; 222 completed the program and were included in analyses. All participants were near or beyond skeletal maturity, representing a population with low residual risk of curve progression. Spinal alignment was assessed by Cobb angle at baseline, 6 months, and 12 months, with monthly clinical evaluations to track progress. Outcomes were analyzed by baseline severity, age, sex, and skeletal maturity (Risser stage) using paired-samples t-tests, repeated-measures ANOVA, subgroup analyses, and multivariable regression. Clinically meaningful improvement was defined as a ≥20% reduction in Cobb angle from baseline. Results: Mean Cobb angle decreased from 18.59° at baseline to 14.85° at 12 months (Δ = −3.74°, 20.3% relative reduction; p < 0.001). The largest improvement occurred in the first 6 months (−3.04°, p < 0.001), followed by a smaller gain between months 6 and 12 (−0.70°, p = 0.012). Patients with milder baseline curves improved more than those with greater deviations (4.45° vs. 3.21°, p < 0.001). Monthly clinical follow-ups suggested gradual improvement between radiographic assessments, though detailed statistical analyses were limited to baseline, 6 months, and 12 months. In multivariable regression, baseline severity remained the only significant predictor of improvement (p < 0.001), while age, sex, and Risser stage were not significant (all p > 0.05). Overall, 24.3% of participants achieved clinically meaningful improvement. Conclusions: A structured 12-month physical therapy program produced significant, sustained improvements in spinal alignment across diverse patient groups. Early intervention in milder curves maximized benefit. These findings support physiotherapy exercise programs as an effective conservative option for scoliosis management.

24 September 2025 in Children
Verified
Journal Article
Open access
PDF file
Osser BrigitteOsser Brigitte
Osser Brigitte
TCToth - Csongor
Toth - Csongor
Carmen Delia Nistor CseppentoCarmen Delia Nistor Cseppento
Carmen Delia Nistor Cseppento
MCMariana Lidia Cevei
Mariana Lidia Cevei
CACristina Aur
Cristina Aur
LRLaura Ioana Rădoi
Laura Ioana Rădoi
Background: Problematic internet use among adolescents is linked to poorer mental health, academic performance, and social functioning, yet evidence from Eastern Europe remains limited. Methods: We conducted a school-based cross-sectional study at a Romanian high school (Arad County) including 308 students aged 15–18 years (154 males, 154 females). Students completed a demographic/behavioral questionnaire and the 20-item Internet Addiction Test (IAT), a widely used measure of problematic internet use. The prespecified primary analysis was a multivariable linear regression of IAT score on sex, age group, residence, daily screen time, prior attempts to reduce use, and main internet purpose; supporting analyses included t-tests, ANOVA, and Pearson correlation (α = 0.05). Results: In bivariable comparisons, males, older adolescents (17–18 years), and urban residents reported higher IAT scores; screen time correlated with IAT (r = 0.460, p < 0.001), and prior reduction attempts were associated with higher scores (Cohen’s d = 0.80). In the adjusted model, male sex (β = 4.97), older age (β = 5.36), greater daily screen time (β = 1.67 per hour), prior attempts to reduce use (β = 4.13), and primarily using the internet for gaming (β = 5.71) remained significant predictors (all p ≤ 0.045); urban residence was not retained (p = 0.218). The model explained 43% of IAT variance (R2 = 0.43). Conclusions: Demographic and behavioral factors independently predict adolescent problematic internet use, highlighting high-risk profiles (older males, heavy screen time, gaming focus, prior reduction attempts). These findings support school-based screening and targeted digital-health interventions in underrepresented contexts.

15 November 2025 in Medicina
Verified
Journal Article
Open access
PDF file
AGAnamaria Gherle
Anamaria Gherle
Carmen Delia Nistor CseppentoCarmen Delia Nistor Cseppento
Carmen Delia Nistor Cseppento
LLLiviu Lazar
Liviu Lazar
ȘDȘtefania Deac
Ștefania Deac
MBMirela Bodea
Mirela Bodea
MCMariana Lidia Cevei
Mariana Lidia Cevei
Background and Objectives: Spinal cord lesion is a severe disorder of the central nervous system, leading to partial or complete interruption of nerve impulse transmission between the brain and the periphery and causing severe neurological and functional deficits. Conventional rehabilitation offers limited outcomes, while robotic gait training (Lokomat®) and Vojta Therapy have shown benefits individually. Evidence on their combined effect remains scarce. To evaluate the combined effect of Vojta Therapy and Lokomat-assisted gait training on motor recovery, functional independence, and quality of life in SCL patients. Materials and Methods: A retrospective clinical study was conducted on 205 patients with traumatic and non-traumatic SCL. Patients were allocated to four groups: (F)—conventional rehabilitation; (V)—conventional + Vojta; (L)—conventional + Lokomat; (VL)—conventional + Vojta + Lokomat. Assessments included the ASIA Impairment Scale (AIS), ASIA motor/sensory scores, spasticity (Modified Ashworth Scale, MAS), functional independence (Functional Independence Measure, FIM), and health-related quality of life (EQ-5D), performed at admission and discharge. Statistical analyses comprised paired t-tests, Wilcoxon signed-rank tests, chi-square tests, Kruskal–Wallis with Dunn’s post hoc corrections, and linear regression. Results: The most frequent lesion levels were C7 (21%) and L1 (20%). All groups showed improvement in FIM scores, with the greatest gains in the VL group (from 79.25 to 84.79, p < 0.05). Post hoc analysis confirmed significantly higher FIM outcomes in VL compared with L. Regression analysis identified the ASIA motor score as the strongest predictor of functional independence (β = 0.76, p < 0.001), with VL group membership adding +10.3 points (p = 0.004). EQ-5D indicated persistent deficits in mobility and self-care, especially in VL patients, consistent with higher lesion severity. Conclusions: Combining Vojta Therapy with Lokomat training provides additional functional benefits compared with Lokomat or Vojta alone. Multimodal individualized rehabilitation appears promising for patients with spinal cord lesions. Prospective randomized controlled trials with long-term follow-up are warranted.

9 November 2026 in Medicina
Verified
Journal Article
Open access
PDF file
STSebastian Tirla
Sebastian Tirla
AGAnamaria Gherle
Anamaria Gherle
MCMariana Lidia Cevei
Mariana Lidia Cevei
LNLaura Corina Nicolescu
Laura Corina Nicolescu
Carmen Delia Nistor CseppentoCarmen Delia Nistor Cseppento
Carmen Delia Nistor Cseppento
Background and Objectives: Chronic low back pain (LBP) is frequently associated with recurrent exacerbations, incomplete symptom resolution, and functional limitations. This study aimed to characterize retrospectively reported symptom patterns over the preceding 12 months in hospitalized adults with chronic LBP and to examine the cross-sectional association between systemic comorbidity burden, assessed using the Age-Adjusted Charlson Comorbidity Index (ACCI), and the absence of sustained pain-free periods. Materials and Methods: This cross-sectional observational study included 97 consecutively enrolled hospitalized patients with chronic LBP (mean age 66.61 ± 10.01 years; 74.2% women; mean body mass index 33.14 ± 6.10 kg/m2). Symptom characteristics over the preceding 12 months, including exacerbation frequency and duration, inter-episode recovery, sustained pain-free periods, and perceived symptom evolution, were assessed using a structured, non-validated clinical questionnaire. Functional limitations were evaluated using a single self-reported item. Comorbidity burden was quantified using the ACCI. Descriptive statistics and 95% confidence intervals (CIs) were calculated, while the association between ACCI and the absence of sustained remission was examined using Spearman correlation and unadjusted binary logistic regression. Results: Frequent exacerbations were reported by 77.3% (95% CI 68.0–84.5) of participants, who experienced at least three episodes annually, including 42.3% reporting six or more episodes. Incomplete inter-episode recovery was reported by 84.5%, while 59.8% (95% CI 49.8–69.0) experienced no sustained pain-free period lasting at least one month. Self-reported functional limitations were present in 92.8% (95% CI 85.8–96.5) of participants, with 56.7% reporting moderate and 36.1% severe limitations. Overall, 66.0% retrospectively reported unchanged or worsening symptoms. The mean ACCI was 3.55 ± 1.75. The association between ACCI and the absence of sustained remission was weak and not statistically significant (Spearman ρ = 0.117, p = 0.253). Unadjusted logistic regression yielded an odds ratio of 1.17 per ACCI point (95% CI 0.92–1.49; p = 0.208). Conclusions: Hospitalized adults with chronic LBP frequently reported recurrent exacerbations, incomplete inter-episode recovery, absence of sustained remission, and substantial perceived functional limitations. No statistically significant association between ACCI and the absence of sustained remission was detected; however, the confidence interval does not exclude a potentially meaningful association. These findings highlight the importance of multidimensional clinical assessment, while the cross-sectional design and retrospective symptom reporting preclude causal, prognostic, or longitudinal interpretations.