The article explores the methods of designing security systems to ensure data confidentiality in telemedicine. The approaches to patient authentication used in tele-health care are considered, with an emphasis on their effectiveness and safety. The analysis of authentication methods, including biometric identification, two-factor authentication and the use of unique identification codes, was carried out. The advantages and disadvantages of each of these methods have been identified, which gives medical organizations the opportunity to make management decisions that best match the structure of information systems and acceptable levels of risk.