Aim of study The NLR is a simple and inexpensive parameter that is useful as a marker of subclinical inflammation. The purpose of this study was to investigate the clinical characteristics of patients diagnosed with acute cerebral ischemia at the time of initial evaluation in the emergency department. Patients and methods The study was designed as a multicentre cross‐sectional study of acute ischemic stroke patients. Neurological evaluations were assessed using the NIHSS and mRS. Evaluations included the results of patients’ laboratory tests performed at the time of presentation to the emergency department. Results Seven hundred and thirty‐five ischemic stroke patients were included in the study. Stroke cases assessed by the mRS as mild or severe showed significant differences with respect to age, leukocyte counts, neutrophil counts, NLR, LDL cholesterol values, and serum glucose values (P = .001). When analysed using NIHSS, lymphocyte levels were significantly higher in very severe stroke cases compared with mild, moderate, and severe cases. NLR was also significantly higher in very severe stroke cases and severe stroke cases as compared with the mild and moderate stroke groups. Neurological evaluations assessed using the mRS showed a mild positive correlation with neutrophil and leukocyte count and a weak correlation with the NLR. Conclusion The NLR exhibited a significant correlation with the results of the mRS and NIHSS. The NLR measured in the very early period was also significantly associated with clinical condition. These results suggest that high NLR values may be a marker of stroke’ severity. What's known Stroke is an important disease that has a significant impact on mortality and morbidity and is closely related to the aging world population. In recent years, highly innovative approaches have been developed in the treatment of stroke. Although a long distance has been covered in the early diagnosis of stroke, the ability to predict the severity of the disease with many parameters is still up to date. What's new At the time of admission, in the absence of infection, parameters such as leukocytelymphocyte count and NLR may be telling about stroke severity. Demonstrating the utility of these simple, practical, inexpensive and naninvasive parameters to predict stroke severity can contribute to the scoring to be established at the time of initial diagnosis.
8 October 2021 in International Journal Of Clinical Practice
Introduction and Aim Stroke is the leading cause of disability in adults and the second most common cause of death, at a rate of 11.8% worldwide. The purpose of this study was to examine the etiological, demographic, and clinical characteristics of patients admitted to hospital due to acute strokes. Materials and Methods This multi-center study retrieved information for all patients admitted to hospital due to an acute cerebrovascular event over a six-month period, and sociodemographic, etiological, and clinical characteristics were recorded. Results A total of 1136 patients, 520 of whom were women (45.7%), with a mean age of 70.3 ± 12.8 years, were included in the study. Of these, 967 were diagnosed with ischemic stroke (IS) (85.1%), 99 with hemorrhagic stroke (HS) (8.7%), and 70 with transient ischemic attack (6.1%). The most common risk factor for stroke was hypertension (73%). Carotid disease and hyperlipidemia rates were higher in patients with HS. Numbers of functionally dependent patients with severe neurological status according to the National Institutes of Health Stroke Scale and modified Rankin scale were significantly higher in the HS group (p <0.001). When IS was classified according to the Trial of Org 10172 in Acute Stroke Treatment, small vessel disease emerged as the nost common cause (41%). The most common lesion localizations were the parietal lobe (23%) in the IS group and the thalamus (35.3%) in the HS group. Eighty-eight patients (7.7%), 62 (6.4%) in the ischemic subgroup, and 26 (26.3%) in the hemorrhagic subgroup, died within the first month. Conclusion Current and accurate evaluations of stroke etiology are essential for stroke prevention and treatment planning. The present study, shows that no change occurred in the etiology of stroke and epidemiological characteristics and that accurate identification of modifiable stroke risk factors is still a major goal.
Amaç: Bu çalışma ile inme ünitesinde yatan hastaların nörolojik durumlarını, yaygın olarak kullanılan fonksiyonel değerlendirme ölçekleri ile takip ederek bu ölçeklerin iyileşmeyi belirlemedeki etkilerini karşılaştırıp sadece yürümenin değil dengenin ve düşme riskinin fonksiyonel iyileşme sürecindeki önemini vurgulamayı amaçladık. Gereç ve Yöntemler: Aydın Devlet Hastanesi İnme Ünitesi’nde yatan ve dahil edilme kriterlerini karşılayan 31 hastanın verileri çalışmaya alındı. Hastaların denge düzeyleri ve postüral kontrolleri; Berg Denge Skalası (BBS) ile nörolojik değerlendirmeleri Ulusal İnme Sağlık Ölçeği Skalası (NIHSS) ile inmeye bağlı dizabiliteleri ise modifiye Rankin Skalası (mRS) ile standardize edildi. Hasta değerlendirmelerinin ilki inme ünitesinden taburcu oldukları gün, ikincisi ise altı ay sonra yapıldı. Bulgular: Çalışma için 50 hasta değerlendirmeye alındı. Ancak çeşitli nedenlerle 19 hasta dışlandı. Verileri analiz edilen 31 hastanın %58’i kadın olup yaş ortalamaları 71,1 ± 11,8 yıldı. Hastaların NIHSS ve mRS skorlarının altı ay sonra anlamlı olarak azaldığı (p
8 September 2021 in International Journal Of Clinical Practice
Amaç: Bu çalışma ile ikinci basamak devlet hastanesi nörofizyoloji laboratuvarına farklı branşlar tarafından yönlendirilen hastaların özellikleri ve klinik ön tanıları ile elektromiyografik(EMG) tanıları arasındaki uyumun değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: 01.03.2014–30.09.2015 tarihlerini kapsayan 18 aylık süre içinde Aydın Devlet Hastanesi Nörofizyoloji Laboratuvarı’nda aynı hekim tarafından yapılan EMG’lerin sonuç raporları retrospektif olarak incelenerek gönderen branşın ön tanısı ve EMG sonuç bilgileri arasındaki uyum analiz edildi. Bulgular: Yaş ortalaması 48.5±15 (5-90) yıl olan hastaların 1620’si (%64.1) kadındı. Nörofizyoloji laboratuvarından; nöroloji 1574 (%62.3), fizik tedavi ve rehabilitasyon (FTR) 534 (%21.1), ortopedi 184 (%7.3), nöroşirürji 155 (%6.1) ve diğer branşlar 81(%3.2) EMG isteminde bulundu. EMG yapılan hastaların ön tanılarının 1027 (%40.6)’si karpal tünel sendromu (KTS), 130 (%5.1)’u kubital tünel sendromu (KUTS), 452 (%17.8)’si polinöropati (PNP), 467 (%18.4)’si üst ekstremite radikülopati (RDP), 198 (%7.8)’i alt ekstremite RDP ‘ydi. Ön tanı-kesin tanı uyumları incelendiğinde: KTS’de %55.6 oran, orta derecede uyum; KUTS’de %65.4 oran, önemli derecede uyum; PNP’de %38.5 oran, orta derecede uyum, üst ekstremite RDP’de %87.1 oran, önemli derecede uyum, alt esktremite RDP’de %81.3 oran, önemli derecede uyum saptandı. Tüm EMG sonuçlarının %25’i normaldi. Nörolojide %27.5, FTR’de %21.7, ortopedide %20.1, nöroşirürjide %11.6 normal sonuç saptandı. Ayrıca KTS’de %27.7, KUTS’de %16.2, PNP’de %48, üst ekstremite RDP’de %6, alt esktremite RDP’de %10.6 normal sonuçlar belirlendi. PNP, en çok oranda (%48) sonucu normal çıkan ön tanı olup istatistiksel olarak anlamlı (p
17 January 2019 in TURKISH JOURNAL OF MEDICAL SCIENCES
Background/aim: This study aimed to investigate the consistency between stroke and general neurologists in subtype assignment using the Trial of ORG-10172 in Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems. Materials and methods: Fifty consecutive acute ischemic stroke patients admitted to the stroke unit were recruited. Patients were classified by two stroke and two general neurologists, each from different medical centers, according to TOAST followed by the CCS. Each neurologist was assessed for consistency and compliance in pairs. Concordance among all four neurologists was investigated and evaluated using the kappa (kappa) value. Results: The kappa (kappa) value of diagnostic compliance between stroke neurologists was 0.61 (95% CI: 0.45-0.77) for TOAST and 0.78 (95% CI: 0.62-0.94) for CSS-5. The kappa (kappa) value was 0.64 (95% CI: 0.48-0.80) for TOAST and 0.75 (95% CI: 0.60-0.91) for CCS-5 for general neurologists. Compliance was moderate [kappa: 0.59 (95% CI: 0.52-0.65)] for TOAST and was strong [kappa: 0.75 (95% CI: 0.68-0.81)] for CCS-5 for all 4 neurologists. 'Cardioembolism' (91.04%) had the highest compliance in both systems. The frequency of the group with 'undetermined etiologies' was less in the CCS (26%) compared to TOAST. Conclusion: The CCS system improved compliance in both stroke and general neurologists compared with TOAST. This suggests that the automatic, evidence-based, easily reproducible CCS system was superior to the TOAST system.